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Commentary

How Did CNBSS Influence Guidelines for So Long and What Can That Teach Us?

Department of Radiology and Diagnostic Imaging, University of Alberta, 2A2.41 WMC 8440-112 Street, Edmonton, Alberta, AB T6G 2B7, Canada
Curr. Oncol. 2022, 29(6), 3922-3932; https://doi.org/10.3390/curroncol29060313
Received: 27 March 2022 / Revised: 23 May 2022 / Accepted: 25 May 2022 / Published: 30 May 2022
(This article belongs to the Special Issue Breast Cancer Imaging and Therapy)
The biased randomization and other quality concerns about the Canadian National Breast Screening Studies (CNBSS) were documented and criticized for decades, even by several individuals very close to the research. CNBSS were the outlier studies among several RCTs of the era and yet were given equal weighting and occasionally higher importance than the remainder of the canon of mammography RCTs. These studies have had an ongoing influence on subsequent evidence review, guideline formation, and, ultimately, patient access to screening. This article explores possible reasons for the ongoing inclusion of CNBSS in the body of mammography screening evidence, discusses the lack of expertise in critical healthcare guideline processes, and, ultimately, suggests several actions and reforms. View Full-Text
Keywords: mammography; mammographic screening; randomization; expertise; guidelines; evidenc; epistemic trespassing; evidence-based medicine mammography; mammographic screening; randomization; expertise; guidelines; evidenc; epistemic trespassing; evidence-based medicine
MDPI and ACS Style

Appavoo, S. How Did CNBSS Influence Guidelines for So Long and What Can That Teach Us? Curr. Oncol. 2022, 29, 3922-3932. https://doi.org/10.3390/curroncol29060313

AMA Style

Appavoo S. How Did CNBSS Influence Guidelines for So Long and What Can That Teach Us? Current Oncology. 2022; 29(6):3922-3932. https://doi.org/10.3390/curroncol29060313

Chicago/Turabian Style

Appavoo, Shushiela. 2022. "How Did CNBSS Influence Guidelines for So Long and What Can That Teach Us?" Current Oncology 29, no. 6: 3922-3932. https://doi.org/10.3390/curroncol29060313

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