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Editorial

Secondary Polycythemia in a Sarcoma Patient: A Commentary about Cediranib

McGill University Health Centre, 1001 Decarie Boulevard, Montreal, QC H4A 3J1, Canada
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Author to whom correspondence should be addressed.
Curr. Oncol. 2019, 26(1), 1-2; https://doi.org/10.3747/co.26.4385
Submission received: 3 November 2018 / Revised: 6 December 2018 / Accepted: 12 January 2019 / Published: 1 February 2019

Excerpt

Note: In lieu of an abstract, this is an excerpt from the first page.

Cediranib, a potent inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, platelet-derived growth factor subunit B, and the c-Kit receptor tyrosine kinase, has shown antitumour activity as an antiangiogenic agent in preclinical models. Initial clinical trials with cediranib in a variety of tumour types, including glioblastoma multiforme, non-small-cell lung cancer, renal cell cancer, colorectal cancer, and prostate cancer, showed activity comparable to that for other vascular endothelial growth factor (vegf) inhibitors, but with significant toxicities, resulting in abandonment of the drug’s development in 2011. [...]

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MDPI and ACS Style

Awan, A.; Alcindor, T. Secondary Polycythemia in a Sarcoma Patient: A Commentary about Cediranib. Curr. Oncol. 2019, 26, 1-2. https://doi.org/10.3747/co.26.4385

AMA Style

Awan A, Alcindor T. Secondary Polycythemia in a Sarcoma Patient: A Commentary about Cediranib. Current Oncology. 2019; 26(1):1-2. https://doi.org/10.3747/co.26.4385

Chicago/Turabian Style

Awan, A., and Thierry Alcindor. 2019. "Secondary Polycythemia in a Sarcoma Patient: A Commentary about Cediranib" Current Oncology 26, no. 1: 1-2. https://doi.org/10.3747/co.26.4385

APA Style

Awan, A., & Alcindor, T. (2019). Secondary Polycythemia in a Sarcoma Patient: A Commentary about Cediranib. Current Oncology, 26(1), 1-2. https://doi.org/10.3747/co.26.4385

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