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Current Oncology
Volume 22
Issue 6
10.3747/co.22.2542
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Current Oncology is published by MDPI from Volume 28 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Multimed Inc..
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Case Report

Isolated Brain Metastases as First Site of Recurrence in Prostate Cancer: Case Report and Review of the Literature

by
J. Craig
1,
J. Woulfe
2,
J. Sinclair
3 and
S. Malone
1,*
1
The Ottawa Hospital Cancer Centre, Ottawa, ON, Canada
2
The Ottawa Hospital, General Site, Ottawa, ON, Canada
3
The Ottawa Hospital, Civic Site, Ottawa, ON, Canada
*
Author to whom correspondence should be addressed.
Curr. Oncol. 2015, 22(6), 493-497; https://doi.org/10.3747/co.22.2542
Submission received: 3 September 2015 / Revised: 5 October 2015 / Accepted: 10 November 2015 / Published: 1 December 2015

Abstract

Fewer than 2% of patients with metastatic prostate cancer (pca) develop brain metastases. Autopsy series have confirmed the rarity of brain metastases. When present, brain metastases occur in end stage, once the pca is castrate-resistant and spread to other sites is extensive. Here, we present a rare case of a patient with pca who developed a solitary parenchymal brain metastasis as first site of relapse 9 years after radical therapy. The patient underwent craniotomy and excision of the tumour. A second recurrence was also isolated to the brain. In the literature, pca patients with brain metastases have a poor mean survival of 1–7.6 months. The patient in our case report experienced a relatively favourable outcome, surviving 19 months after his initial brain relapse.
Keywords: prostate cancer; brain metastasis; recurrence prostate cancer; brain metastasis; recurrence

Share and Cite

MDPI and ACS Style

Craig, J.; Woulfe, J.; Sinclair, J.; Malone, S. Isolated Brain Metastases as First Site of Recurrence in Prostate Cancer: Case Report and Review of the Literature. Curr. Oncol. 2015, 22, 493-497. https://doi.org/10.3747/co.22.2542

AMA Style

Craig J, Woulfe J, Sinclair J, Malone S. Isolated Brain Metastases as First Site of Recurrence in Prostate Cancer: Case Report and Review of the Literature. Current Oncology. 2015; 22(6):493-497. https://doi.org/10.3747/co.22.2542

Chicago/Turabian Style

Craig, J., J. Woulfe, J. Sinclair, and S. Malone. 2015. "Isolated Brain Metastases as First Site of Recurrence in Prostate Cancer: Case Report and Review of the Literature" Current Oncology 22, no. 6: 493-497. https://doi.org/10.3747/co.22.2542

APA Style

Craig, J., Woulfe, J., Sinclair, J., & Malone, S. (2015). Isolated Brain Metastases as First Site of Recurrence in Prostate Cancer: Case Report and Review of the Literature. Current Oncology, 22(6), 493-497. https://doi.org/10.3747/co.22.2542

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