Are Matrix Metalloproteinases Relevant Therapeutic Targets for Prostate Cancer Bone Metastasis?

R.D. Bonfil; R. Fridman; S. Mobashery; M.L. Cher

doi:10.3747/co.v15i4.216

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Article

1 August 2008

Are Matrix Metalloproteinases Relevant Therapeutic Targets for Prostate Cancer Bone Metastasis?

and

Department of Urology, Wayne State University School of Medicine, and The Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA

Department of Pathology, Wayne State University School of Medicine, and The Barbara Ann Karmanos Cancer Institute, Detroit, MI, USA

Department of Chemistry and Biochemistry, and the Walther Cancer Research Center, University of Notre Dame, Notre Dame, IN, USA

Author to whom correspondence should be addressed.

Curr. Oncol.2008, 15(4), 188-192;https://doi.org/10.3747/co.v15i4.216

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Abstract

After basal and squamous cell skin cancers, prostate cancer is the most frequent cancer in men in the United States, with 186,320 men estimated to be diagnosed with the disease and 28,660 expected to die from it in 2008 ¹. [...]

Keywords:

matrix metalloproteinases; prostate cancer; bone metastasis

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