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Cardiovascular Medicine
Volume 7
Issue 4
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Cardiovascular Medicine is published by MDPI from Volume 28 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Editores Medicorum Helveticorum (EMH).

Cardiovasc. Med., Volume 7, Issue 4 (04 2004) – 5 articles

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1 pages, 99 KB  
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Tachycardie Ventriculaire Infundibulaire
by Juan Sztajzel
Cardiovasc. Med. 2004, 7(4), 187; https://doi.org/10.4414/cvm.2004.01021 - 28 Apr 2004
Viewed by 64
Abstract
Il s'agit d'un patient de 54 ans, fumeur, hospitalis é en urgence pour des palpitations avec oppression rétrosternale. [...] Full article
2 pages, 139 KB  
Case Report
Hypereosinophilia and Brightness, not just a Failing Heart
by Stéphane Cook and Peter Wenaweser
Cardiovasc. Med. 2004, 7(4), 185; https://doi.org/10.4414/cvm.2004.01020 - 28 Apr 2004
Viewed by 64
Abstract
A 66-year-old woman was admitted with NYHA class II congestive heart failure, oedema of the lower extremities, and slight jugular vein enlargement. [...] Full article
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4 pages, 126 KB  
Editorial
Bedeutung und Epidemiologie der Endokarditis
by Thomas D. Szucs and Gieri Cathomas
Cardiovasc. Med. 2004, 7(4), 181; https://doi.org/10.4414/cvm.2004.01022 (registering DOI) - 28 Apr 2004
Viewed by 42
Abstract
Die Pathogenese der infektiösen Endokarditis wurde 1885 auf nahezu visionäre Weise von Sir Wiliam Osler ausführlich beschrieben. Trotzdem brauchte es fast ein Jahrhundert, um die Richtigkeit dieser Abläufe mit Studien zu belegen. Die epidemiologischen Merkmale der infektiösen Endokarditis, einer mikrobiologischen Infektion der inneren [...] Read more.
Die Pathogenese der infektiösen Endokarditis wurde 1885 auf nahezu visionäre Weise von Sir Wiliam Osler ausführlich beschrieben. Trotzdem brauchte es fast ein Jahrhundert, um die Richtigkeit dieser Abläufe mit Studien zu belegen. Die epidemiologischen Merkmale der infektiösen Endokarditis, einer mikrobiologischen Infektion der inneren Herzoberfläche, verändern sich in den entwickelten Ländern als Folge steigender Lebenserwartung, neuer prädisponierender Faktoren und steigender Anzahl der nosokomialen Fälle. Trotz der Verbesserungen in Diagnostik und Therapie bleibt die infektiöse Endokarditis jedoch eine ernstzunehmende Erkrankung. Full article
7 pages, 134 KB  
Article
Cost-Effectiveness of Clopidogrel in Patients with Acute Coronary Syndrome in Switzerland
by Andreas Frei, Peter Lindgren and Bernhard Meier
Cardiovasc. Med. 2004, 7(4), 174; https://doi.org/10.4414/cvm.2004.01024 - 28 Apr 2004
Cited by 2 | Viewed by 49
Abstract
Background: The results of the Clopidogrel in Unstable Angina to prevent Recurrent Events (CURE)-trial have demonstrated that the use of clopidogrel in addition to standard treatment with acetylsalicyl-acid (ASA) alone has led to a reduction in the incidence of events defined as cardiovascular [...] Read more.
Background: The results of the Clopidogrel in Unstable Angina to prevent Recurrent Events (CURE)-trial have demonstrated that the use of clopidogrel in addition to standard treatment with acetylsalicyl-acid (ASA) alone has led to a reduction in the incidence of events defined as cardiovascular death, myocardial infarction and stroke in patients with unstable angina. The aim of this study was to examine the cost-effectiveness of this treatment strategy. Methods: Resource use was identified from the case report forms (CRFs) of all patients in the CURE study and grouped into initial hospitalisation, re-hospitalisations, study drug, and concomitant medications. The initial and re-hospitalisations were assigned to a diagnosis related group (DRG) in a blinded automated fashion. Clopidogrel uptake was assessed based on the number of days on treatment. To assess concomitant medication use recommended doses and durations were applied, since on the CRFs only yes/no answers were recorded. Hospitalisations were assigned a DRG specific flat rate based on the costweights of the Swiss All Patient Diagnosis Related Groups (APDRG). The study drug and concomitant medication were valued at retail prices. The number of life years saved was estimated using the DEALE-approximation. Results: Patients in the clopidogrel + ASA arm have on average slightly higher costs than patients treated with ASA alone, CHF 14,839 as compared to CHF 14,380. This is due to the acquisition cost of clopidogrel (CHF 775) which is partly offset by savings during the initial and subsequent hospitalisations. These cost offsets were CHF 327, the other costs were quite similar in both groups. Treatment with clopidogrel led to 0.12 life years saved. The incremental cost-effectiveness, i.e., the incremental cost per life year saved, of clopidogrel and ASA over ASA alone was CHF 3810. This is comparable to other cost-effective therapies in cardiovascular disease. Full article
15 pages, 439 KB  
Editorial
Plättchenhemmung Durch Thienopyridine beim Akuten Koronarsyndrom und nach Perkutaner Koronarer Intervention—Praktische Empfehlungen
by Roberto Corti, Lukas E. Spieker, François Mach, Paul Erne, Tiziano Moccetti, Jürg Beer, Phillip Urban, Peter Buser, Peter Rickenbacher, Franz R. Eberli, Ulrich Sigwart, Patrick Hunziker, Angehrn Walter, Lukas Kappenberger, Osmund Bertel, Stephan Windecker, K. J. Clemetson, Bernhard Meier and Thomas F. Lüscher
Cardiovasc. Med. 2004, 7(4), 159; https://doi.org/10.4414/cvm.2004.01023 - 28 Apr 2004
Viewed by 54
Abstract
Thienopyridine platelet antagonists in acute coronary syndrome and after PCI–practical recommendations Full article
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