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Cardiovascular Medicine
Volume 15
Issue 5
10.4414/cvm.2012.01665
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Cardiovascular Medicine is published by MDPI from Volume 28 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Editores Medicorum Helveticorum (EMH).
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Review

New Anticoagulants for the Prevention and Therapy of Venous Thromboembolism—A Review

by
Nazanin Sédille-Mostafaie
and
Wolfgang Korte
*
Centre for Laboratory Medicine, Kantonsspital St. Gallen, CH-9007 St. Gallen, Switzerland
*
Author to whom correspondence should be addressed.
Cardiovasc. Med. 2012, 15(5), 147; https://doi.org/10.4414/cvm.2012.01665
Submission received: 16 February 2012 / Revised: 16 March 2012 / Accepted: 16 April 2012 / Published: 16 May 2012
Versions Notes

Abstract

Thrombin plays an essential role in haemostasis and thrombosis; therefore, anticoagulant strategies focus on direct or indirect inhibition of thrombin or factor Xa. Over the last 60 years, key players in antithrombotic treatment have been unfractionated heparin and vitamin K antagonists (VAKs), such as coumarin. New oral anticoagulants, with different mechanisms of action and administration, have the potential to promote dramatic changes in the management of patients with venous thromboembolic disease. This review provides an overview of the newer anticoagulants likely to be used in this indication.
Keywords: new oral anticoagulations; venous thromboembolism; prophylaxis; therapy new oral anticoagulations; venous thromboembolism; prophylaxis; therapy

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MDPI and ACS Style

Sédille-Mostafaie, N.; Korte, W. New Anticoagulants for the Prevention and Therapy of Venous Thromboembolism—A Review. Cardiovasc. Med. 2012, 15, 147. https://doi.org/10.4414/cvm.2012.01665

AMA Style

Sédille-Mostafaie N, Korte W. New Anticoagulants for the Prevention and Therapy of Venous Thromboembolism—A Review. Cardiovascular Medicine. 2012; 15(5):147. https://doi.org/10.4414/cvm.2012.01665

Chicago/Turabian Style

Sédille-Mostafaie, Nazanin, and Wolfgang Korte. 2012. "New Anticoagulants for the Prevention and Therapy of Venous Thromboembolism—A Review" Cardiovascular Medicine 15, no. 5: 147. https://doi.org/10.4414/cvm.2012.01665

APA Style

Sédille-Mostafaie, N., & Korte, W. (2012). New Anticoagulants for the Prevention and Therapy of Venous Thromboembolism—A Review. Cardiovascular Medicine, 15(5), 147. https://doi.org/10.4414/cvm.2012.01665

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