Spontaneous Remission of Acute Myeloid Leukemia: A Case Report
Abstract
1. Introduction
2. Case Description
3. Methods
4. Results and Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Dunbar, A.J.; Rampal, R.K.; Levine, R. Leukemia secondary to myeloproliferative neoplasms. Blood 2020, 136, 61–70. [Google Scholar] [CrossRef] [PubMed]
- Rashidi, A.; Fisher, S.I. Spontaneous remission of acute myeloid leukemia. Leuk. Lymphoma 2015, 56, 1727–1734. [Google Scholar] [CrossRef] [PubMed]
- Gardin, C.; Dombret, H. Hypomethylating Agents as a Therapy for AML. Curr. Hematol. Malign-Rep. 2017, 12, 1–10. [Google Scholar] [CrossRef] [PubMed]
- Dombret, H.; Seymour, J.F.; Butrym, A.; Wierzbowska, A.; Selleslag, D.; Jang, J.H.; Kumar, R.; Cavenagh, J.; Schuh, A.C.; Candoni, A.; et al. International phase 3 study of azacitidine vs conventional care regimens in older patients with newly diagnosed AML with >30% blasts. Blood 2015, 126, 291–299. [Google Scholar] [CrossRef] [PubMed]
- Milosevic, J.D.; Puda, A.; Malcovati, L.; Berg, T.; Hofbauer, M.; Stukalov, A.; Klampfl, T.; Harutyunyan, A.; Gisslinger, H.; Gisslinger, B.; et al. Clinical significance of genetic aberrations in secondary acute myeloid leukemia. Am. J. Hematol. 2012, 87, 1010–1016. [Google Scholar] [CrossRef]
- Rampal, R.; Ahn, J.; Abdel-Wahab, O.; Nahas, M.; Wang, K.; Lipson, D.; Otto, G.A.; Yelensky, R.; Hricik, T.; McKenney, A.S.; et al. Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms. Proc. Natl. Acad. Sci. USA 2014, 111, E5401–E5410. [Google Scholar] [CrossRef] [PubMed]
- Courtier, F.; Carbuccia, N.; Garnier, S.; Guille, A.; Adélaïde, J.; Cervera, N.; Gelsi-Boyer, V.; Mozziconacci, M.J.; Rey, J.; Vey, N.; et al. Genomic analysis of myeloproliferative neoplasms in chronic and acute phases. Haematologica 2017, 102, e11–e14. [Google Scholar] [CrossRef] [PubMed]
- Abdel-Wahab, O.; Manshouri, T.; Patel, J.; Harris, K.; Yao, J.; Hedvat, C.; Heguy, A.; Bueso-Ramos, C.; Kantarjian, H.; Levine, R.L.; et al. Genetic Analysis of Transforming Events That Convert Chronic Myeloproliferative Neoplasms to Leukemias. Cancer Res. 2010, 70, 447–452. [Google Scholar] [CrossRef] [PubMed]
- Zeng, Q.; Yuan, Y.; Li, P.; Chen, T. Spontaneous Remission in Patients with Acute Myeloid Leukemia with t(8;21) or Cutaneous Myeloid Sarcoma: Two Case Reports and a Review of the Literature. Intern. Med. 2013, 52, 1227–1233. [Google Scholar] [CrossRef] [PubMed][Green Version]
- Cruijsen, M.; Lübbert, M.; Wijermans, P.; Huls, G. Clinical Results of Hypomethylating Agents in AML Treatment. J. Clin. Med. 2014, 4, 1–17. [Google Scholar] [CrossRef] [PubMed]
- Vachhani, P.; Mendler, J.H.; Evans, A.; Deeb, G.; Starostik, P.; Wallace, P.; Wang, E.S. Spontaneous Remission in an Older Patient with RelapsedFLT3ITD Mutant AML. Case Rep. Hematol. 2016, 2016, 1259759. [Google Scholar] [CrossRef] [PubMed]
- Tzankov, A.; Ludescher, C.; Duba, H.-C.; Steinlechner, M.; Knapp, R.; Schmid, T.; Grünewald, K.; Gastl, G.; Stauder, R. Spontaneous remission in a secondary acute myelogenous leukaemia following invasive pulmonary aspergillosis. Ann. Hematol. 2001, 80, 423–425. [Google Scholar] [CrossRef] [PubMed]
- Fassas, A.; Sakellari, I.; Anagnostopoulos, A.; Saloum, R. Spontaneous remission of acute myeloid leukemia in a patient with concurrent Pneumocystis carinii pneumonia. Nouv. Rev. Fr. Hematol. 1991, 33, 363–364. [Google Scholar] [PubMed]
- Mitterbauer, M.; Fritzer-Szekeres, M.; Simonitsch, I.; Knöbl, P.; Rintelen, C.; Schwarzinger, I.; Haas, O.A.; Silberbauer, K.; Frey, K.; Bibus, B.; et al. Spontaneous remission of acute myeloid leukemia after infection and blood transfusion associated with hypergammaglobulinaemia. Ann. Hematol. 1996, 73, 189–193. [Google Scholar] [CrossRef] [PubMed]
- Jimemez, C.; Ribera, J.; Abad, E.; Pintos-Morell, G.; Milla, F.; Junca, J.; Feliu, E. Increased serum tumour necrosis factor during transient remission in acute leukaemia. Lancet 1993, 341, 1600. [Google Scholar] [CrossRef]
- Mozafari, R.; Moeinian, M.; Asadollahi-Amin, A. Spontaneous Complete Remission in a Patient with Acute Myeloid Leukemia and Severe Sepsis. Case Rep. Hematol. 2017, 2017, 9593750. [Google Scholar] [CrossRef] [PubMed]
- Bergmann, J.; Schoch, C.; Ludwig, W.-D.; Reiter, A.; Hastka, J.; Lengfelder, E.; Hehlmann, R.; Maywald, O.; Buchheidt, D. Spontaneous remission in adult acute myeloid leukemia in association with systemic bacterial infection—Case report and review of the literature. Ann. Hematol. 2004, 83, 189–194. [Google Scholar] [CrossRef]
- Camus, V.; Etancelin, P.; Jardin, F.; Lenain, P.; Contentin, N.; Daliphard, S.; Buchonnet, G.; Lemasle, E.; Lanic, H.; Leprêtre, S.; et al. Spontaneous remission in three cases of AML M5 with NPM 1 mutation. Clin. Case Rep. 2015, 3, 955–959. [Google Scholar] [CrossRef]
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. |
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Martínez-Díez, Y.; Franganillo-Suárez, A.; Salgado-Sánchez, R.; Atance-Pasarisas, M.; Blas, C.; Cotti-Ferrari, M.J.; Castaño-Bonilla, T.; Lainez-González, D.; Rodríguez-Pinilla, S.M.; Llamas-Sillero, P.; et al. Spontaneous Remission of Acute Myeloid Leukemia: A Case Report. Medicina 2022, 58, 921. https://doi.org/10.3390/medicina58070921
Martínez-Díez Y, Franganillo-Suárez A, Salgado-Sánchez R, Atance-Pasarisas M, Blas C, Cotti-Ferrari MJ, Castaño-Bonilla T, Lainez-González D, Rodríguez-Pinilla SM, Llamas-Sillero P, et al. Spontaneous Remission of Acute Myeloid Leukemia: A Case Report. Medicina. 2022; 58(7):921. https://doi.org/10.3390/medicina58070921
Chicago/Turabian StyleMartínez-Díez, Yolanda, Aida Franganillo-Suárez, Rocío Salgado-Sánchez, Mireia Atance-Pasarisas, Carlos Blas, María José Cotti-Ferrari, Tamara Castaño-Bonilla, Daniel Lainez-González, Socorro María Rodríguez-Pinilla, Pilar Llamas-Sillero, and et al. 2022. "Spontaneous Remission of Acute Myeloid Leukemia: A Case Report" Medicina 58, no. 7: 921. https://doi.org/10.3390/medicina58070921
APA StyleMartínez-Díez, Y., Franganillo-Suárez, A., Salgado-Sánchez, R., Atance-Pasarisas, M., Blas, C., Cotti-Ferrari, M. J., Castaño-Bonilla, T., Lainez-González, D., Rodríguez-Pinilla, S. M., Llamas-Sillero, P., & Alonso-Dominguez, J. M. (2022). Spontaneous Remission of Acute Myeloid Leukemia: A Case Report. Medicina, 58(7), 921. https://doi.org/10.3390/medicina58070921