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Pharmaceuticals, Volume 4, Issue 1

January 2011 - 12 articles

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Articles (12)

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Review

31 Citations

10,579 Views

25 Pages

Blocking Plasmodium falciparum Malaria Transmission with Drugs: The Gametocytocidal and Sporontocidal Properties of Current and Prospective Antimalarials

Anthony E. Kiszewski

Pharmaceuticals2011, 4(1), 44-68;https://doi.org/10.3390/ph4010044

23 December 2010

Drugs that kill or inhibit the sexual stages of Plasmodium could potentially amplify or synergize the impact of other interventions by blocking transmission to mosquitoes. Primaquine and other 8-aminoquinolines have long offered such potential, but s...

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Review

37 Citations

10,648 Views

22 Pages

Drug Induced Hypersensitivity and the HLA Complex

Ana Alfirevic and
Munir Pirmohamed

Pharmaceuticals2011, 4(1), 69-90;https://doi.org/10.3390/ph4010069

23 December 2010

Drug-induced hypersensitivity reactions are of major concern and present a burden for national healthcare systems due to their often severe nature, high rate of hospital admissions and high mortality. They manifest with a wide range of symptoms and s...

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