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Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes

Departamento de Química, Área de Química Analítica, Facultad de Ciencias, Universidad de Burgos, Plaza Misael Bañuelos s/n, E-09001 Burgos, Spain
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Sensors 2008, 8(7), 4201-4212; https://doi.org/10.3390/s8074201
Received: 5 June 2008 / Revised: 25 June 2008 / Accepted: 10 July 2008 / Published: 15 July 2008
This paper describes a procedure that has been optimized for the determination of lamotrigine by Differential Pulse Adsorptive Stripping Voltammetry (DPAdSV) using carbon screen-printed electrodes (CSPE) and mercury coated carbon screen-printed electrodes. Selection of the experimental parameters was made using experimental design methodology. The detection limit found was 5.0 x 10-6 M and 2.0 x 10-6 M for the non modified and Hg modified CSPE, respectively. In terms of reproducibility, the precision of the above mentioned methods was calculated in %RSD values at 9.83% for CSPE and 2.73% for Hg-CSPE. The Hg-coated CSPEs developed in this work were successfully applied in the determination of lamotrigine in pharmaceutical preparations. View Full-Text
Keywords: lamotrigine; screen-printed electrodes; differential pulse adsorptive stripping voltammetry. lamotrigine; screen-printed electrodes; differential pulse adsorptive stripping voltammetry.
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MDPI and ACS Style

Domínguez-Renedo, O.; Calvo, M.E.B.; Arcos-Martínez, M.J. Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes. Sensors 2008, 8, 4201-4212. https://doi.org/10.3390/s8074201

AMA Style

Domínguez-Renedo O, Calvo MEB, Arcos-Martínez MJ. Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes. Sensors. 2008; 8(7):4201-4212. https://doi.org/10.3390/s8074201

Chicago/Turabian Style

Domínguez-Renedo, Olga, M. E.B. Calvo, and M. J. Arcos-Martínez 2008. "Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes" Sensors 8, no. 7: 4201-4212. https://doi.org/10.3390/s8074201

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