N′-(5-Bromofuran-2-carbonyl)isonicotinohydrazide

Round 1

Reviewer 1 Report

The reviewer wrote his comments in the attached file.

Comments for author File: Comments.pdf

Author Response

Many thanks for the comments. We have revised the manuscript and supplementary materials. 

Reviewer 2 Report

The manuscript seems to be good.

Author Response

Many thanks for the positive comments. 

Reviewer 3 Report

The reviewed paper concerns the synthesis of an isonicotinohydrazide derivative. This is an interesting extension of the current state of knowledge, however, I have a few questions and suggestions for the Authors:

- some language corrections are needed:

"Furan carboxamides are furan amides" sounds quite strange

lines 21-22: "thionyl chloride as a coupling agent [6], which not only produces"

- what IR technique did you use (ATR, nujol, KBr pellets...)?

- what about the MS analysis? the deviation in ppm should be less than 5 ppm, and you have about 18 ppm (the isotopic profile also differs slightly: [M]:[M+2] should be almost 1:1 (intensity).

- what about the optimization of the reaction conditions? did you check the ratios of the reagents?

- References- please check the journal abbreviations (once you give the full name and once the abbreviation)

- I suggest adding a title page with authors and affiliations to the supporting information; I think, full 1H and 13C NMR spectra (not just expansions) are necessary to check the purity of the sample.

Minor editing of English language required

Author Response

Please see the attachment.

Author Response File: Author Response.pdf