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Synthesis of Benzyl 2-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)acetate

Department of Medicinal Chemistry, Victorian College of Pharmacy, Monash University, 381 Royal Parade, Parkville, Victoria, 3052, Australia
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Molbank 2005, 2005(6), M453; https://doi.org/10.3390/M453
Received: 24 November 2005 / Accepted: 7 December 2005 / Published: 12 December 2005
Note: In lieu of an abstract, this is an excerpt from the first page.

As part of our research programme, we have synthesized the title compound as an intermediate for the preparation of a zwitterionic analogue of the atypical antipsychotic, clozapine.[...] View Full-Text
Keywords: clozapine; amidine; benzyl ester; N-alkylation; dibenzodiazepine clozapine; amidine; benzyl ester; N-alkylation; dibenzodiazepine
MDPI and ACS Style

Camerino, M.A.; Capuano, B.; Crosby, I.T.; Lloyd, E.J. Synthesis of Benzyl 2-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)acetate. Molbank 2005, 2005, M453.

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