Next Article in Journal
Addressing Doxorubicin Resistance in Bone Sarcomas Using Novel Drug-Resistant Models
Previous Article in Journal
Palladium Decorated N-Doped Carbon Foam as a Highly Active and Selective Catalyst for Nitrobenzene Hydrogenation
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
IJMS
Volume 23
Issue 12
10.3390/ijms23126424
ijms-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Synthesis of Gold-Platinum Core-Shell Nanoparticles Assembled on a Silica Template and Their Peroxidase Nanozyme Properties

by
Xuan-Hung Pham
1,
Van-Khue Tran
2,
Eunil Hahm
1,
Yoon-Hee Kim
1,
Jaehi Kim
1,
Wooyeon Kim
1 and
Bong-Hyun Jun
1,*
1
Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Korea
2
VNUK Institute for Research and Executive Education, The University of Danang, Danang 550 000, Vietnam
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2022, 23(12), 6424; https://doi.org/10.3390/ijms23126424
Submission received: 27 April 2022 / Revised: 3 June 2022 / Accepted: 6 June 2022 / Published: 8 June 2022
(This article belongs to the Section Molecular Nanoscience)
Browse Figures
Review Reports Versions Notes

Abstract

Bimetallic nanoparticles are important materials for synthesizing multifunctional nanozymes. A technique for preparing gold-platinum nanoparticles (NPs) on a silica core template (SiO2@Au@Pt) using seed-mediated growth is reported in this study. The SiO2@Au@Pt exhibits peroxidase-like nanozyme activity has several advantages over gold assembled silica core templates (SiO2@Au@Au), such as stability and catalytic performance. The maximum reaction velocity (Vmax) and the Michaelis–Menten constants (Km) were and 2.1 × 10−10 M−1∙s−1 and 417 µM, respectively. Factors affecting the peroxidase activity, including the quantity of NPs, solution pH, reaction time, and concentration of tetramethyl benzidine, are also investigated in this study. The optimization of SiO2@Au@Pt NPs for H2O2 detection obtained in 0.5 mM TMB; using 5 µg SiO2@Au@Pt, at pH 4.0 for 15 min incubation. H2O2 can be detected in the dynamic liner range of 1.0 to 100 mM with the detection limit of 1.0 mM. This study presents a novel method for controlling the properties of bimetallic NPs assembled on a silica template and increases the understanding of the activity and potential applications of highly efficient multifunctional NP-based nanozymes.
Keywords: gold-platinum bimetallic nanoparticles; nanoparticle; gold-platinum-assembled silica nanostructures; nanozyme; peroxidase-like activity gold-platinum bimetallic nanoparticles; nanoparticle; gold-platinum-assembled silica nanostructures; nanozyme; peroxidase-like activity

Share and Cite

MDPI and ACS Style

Pham, X.-H.; Tran, V.-K.; Hahm, E.; Kim, Y.-H.; Kim, J.; Kim, W.; Jun, B.-H. Synthesis of Gold-Platinum Core-Shell Nanoparticles Assembled on a Silica Template and Their Peroxidase Nanozyme Properties. Int. J. Mol. Sci. 2022, 23, 6424. https://doi.org/10.3390/ijms23126424

AMA Style

Pham X-H, Tran V-K, Hahm E, Kim Y-H, Kim J, Kim W, Jun B-H. Synthesis of Gold-Platinum Core-Shell Nanoparticles Assembled on a Silica Template and Their Peroxidase Nanozyme Properties. International Journal of Molecular Sciences. 2022; 23(12):6424. https://doi.org/10.3390/ijms23126424

Chicago/Turabian Style

Pham, Xuan-Hung, Van-Khue Tran, Eunil Hahm, Yoon-Hee Kim, Jaehi Kim, Wooyeon Kim, and Bong-Hyun Jun. 2022. "Synthesis of Gold-Platinum Core-Shell Nanoparticles Assembled on a Silica Template and Their Peroxidase Nanozyme Properties" International Journal of Molecular Sciences 23, no. 12: 6424. https://doi.org/10.3390/ijms23126424

APA Style

Pham, X.-H., Tran, V.-K., Hahm, E., Kim, Y.-H., Kim, J., Kim, W., & Jun, B.-H. (2022). Synthesis of Gold-Platinum Core-Shell Nanoparticles Assembled on a Silica Template and Their Peroxidase Nanozyme Properties. International Journal of Molecular Sciences, 23(12), 6424. https://doi.org/10.3390/ijms23126424

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop