Meta-Analysis of Early Nutrition: The Benefits of Enteral Feeding Compared to a Nil Per Os Diet Not Only in Severe, but Also in Mild and Moderate Acute Pancreatitis
Abstract
:1. Introduction
2. Results
2.1. Severe Acute Pancreatitis (SAP) Group
2.2. Mild and Moderate Acute Pancreatitis (MAP) Group
3. Discussion
4. Materials and Methods
4.1. Article Search
4.1.1. PICO (Problem, Intervention, Comparison, Outcome)
4.1.2. Search
4.1.3. Inclusions and Exclusions
4.1.4. Statistical Analyses
5. Conclusions
Supplementary Materials
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Points | Mortality (%) | Organ Failure (%) | Intervention (%) | CRP (mg/L) | WCC (109/L) | SIRS (%) |
0 | 0–0.9 | 0–0.09 | 0–0.09 | 0–19.9 | 4000–9999.9 | 0–0.09 |
1 | 1–2.9 | 0.1–0.19 | 0.1–0.19 | 20–39.9 | 10,000–11,999 | 0.1–0.14 |
2 | 3–4.9 | 0.2–0.29 | 0.2–0.29 | 40–59.9 | 12,000–13,999 | 0.15–0.19 |
3 | 5–6.9 | 0.3– | 0.3–0.39 | 60–79.9 | 14,000–15,999 | 0.2–0.24 |
4 | 7–8.9 | 0.4–0.49 | 80–99.9 | 16,000–17,999 | 0.25–0.29 | |
5 | 9– | 0.5– | 100– | 18,000– | 0.3– | |
Points | LOH (Days) | Necrosis (%) | Infection (%) | Hospital Readmission (%) | Progression of Severity (%) | Pain Relapse (%) |
0 | 0–4.9 | 0–0.09 | 0–0.09 | 0–0.04 | 0–0.04 | 0–0.09 |
1 | 5–9.9 | 0.1–0.19 | 0.1–0.19 | 0.05–0.06 | 0.05–0.06 | 0.1–0.19 |
2 | 10–12.4 | 0.2–0.29 | 0.2– | 0.07–0.08 | 0.07–0.08 | 0.2–0.29 |
3 | 12.5–14.9 | 0.3– | – | 0.09–0.10 | 0.09–0.10 | 0.3–0.39 |
4 | 15–19.9 | – | – | 0.11– | 0.11– | 0.4– |
5 | 20– | – | – | – | – | – |
Points | VAS-Pain | Nausea/Vomiting (%) | Antibiotics (%) | Opiate-Free Treatment (%) | Start of Oral Intake (%) | |
0 | 0–1 | 0–0.18 | 0–0.09 | 0–0.09 | 0–0.04 | |
1 | 2–4 | 0.2–0.39 | 0.1–0.19 | 0.1–0.19 | 0.05–0.09 | |
2 | 5–7 | 0.4–0.59 | 0.2–0.29 | 0.2–0.29 | 0.1–0.14 | |
3 | 8–9 | 0.6–0.79 | 0.3–0.39 | 0.3–0.39 | 0.15–0.19 | |
4 | – | 0.8– | 0.4– | 0.4–0.49 | 0.2–0.24 | |
5 | – | – | – | 0.5– | 0.25– |
Article | MAP | SAP | EN | NPO | RCT |
---|---|---|---|---|---|
Doley et al. 2009 [16] | – | ✔ | ✔ | ✔ | ✔ |
Eckerwall et al. 2006 [17] | – | ✔ | ✔ | ✔ | ✔ |
Kalfarentzos et al. 1997 [18] | – | ✔ | ✔ | ✔ | ✔ |
Sun et al. 2004 [19] | – | ✔ | ✔ | ✔ | ✔ |
Sun et al. 2013 [20] | – | ✔ | ✔ | ✔ | ✔ |
Wang et al. 2013 [21] | – | ✔ | ✔ | ✔ | ✔ |
Wu et al. 2010 [22] | – | ✔ | ✔ | ✔ | ✔ |
Abou-assi et al. 2002 [23] | ✔ | – | ✔ | ✔ | ✔ |
Eckerwall et al. 2007 [24] | ✔ | – | ✔ | ✔ | ✔ |
McClave et al. 1997 [25] | ✔ | – | ✔ | ✔ | ✔ |
Oláh et al. 2002 [26] | ✔ | – | ✔ | ✔ | ✔ |
Petrov et al. 2013 [27] | ✔ | – | ✔ | ✔ | ✔ |
Ma et al. 2016 [29] | ✔ | – | ✔ | ✔ | ✔ |
Li et al. 2013 [39] | ✔ | – | ✔ | – | ✔ |
Ockenga et al. 2002 [41] | ✔ | – | – | ✔ | ✔ |
Pandey et al. 2004 [42] | ✔ | – | ✔ | – | ✔ |
Pongratz et al. 2013 [45] | ✔ | – | – | ✔ | ✔ |
Sathiaraj et al. 2008 [46] | ✔ | – | ✔ | – | ✔ |
Wu et al. 2011 [49] | ✔ | – | – | ✔ | ✔ |
Andersson et al. 2006 [31] | – | ✔ | – | ✔ | – |
Bakker OJ et al. 2014 [32] | – | ✔ | ✔ | – | ✔ |
Besselink et al. 2008 [33] | – | ✔ | ✔ | – | ✔ |
Eatock et al. 2005 [34] | – | ✔ | ✔ | – | ✔ |
He et al. 2004 [35] | – | ✔ | – | ✔ | ✔ |
Karakan et al. 2007 [36] | – | ✔ | ✔ | – | ✔ |
Kumar et al. 2006 [37] | – | ✔ | ✔ | – | ✔ |
Kyhala et al. 2012 [38] | – | ✔ | – | ✔ | ✔ |
Modena et al. 2006 [40] | – | ✔ | ✔ | ✔ | – |
Pearce et al. 2006 [43] | – | ✔ | ✔ | – | ✔ |
Pettila et al. 2010 [44] | – | ✔ | – | ✔ | ✔ |
Singh et al. 2012 [47] | – | ✔ | ✔ | – | ✔ |
Vege et al. 2015 [48] | – | ✔ | – | ✔ | ✔ |
Zhao et al. 2013 [50] | – | ✔ | – | ✔ | ✔ |
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Márta, K.; Farkas, N.; Szabó, I.; Illés, A.; Vincze, Á.; Pár, G.; Sarlós, P.; Bajor, J.; Szűcs, Á.; Czimmer, J.; et al. Meta-Analysis of Early Nutrition: The Benefits of Enteral Feeding Compared to a Nil Per Os Diet Not Only in Severe, but Also in Mild and Moderate Acute Pancreatitis. Int. J. Mol. Sci. 2016, 17, 1691. https://doi.org/10.3390/ijms17101691
Márta K, Farkas N, Szabó I, Illés A, Vincze Á, Pár G, Sarlós P, Bajor J, Szűcs Á, Czimmer J, et al. Meta-Analysis of Early Nutrition: The Benefits of Enteral Feeding Compared to a Nil Per Os Diet Not Only in Severe, but Also in Mild and Moderate Acute Pancreatitis. International Journal of Molecular Sciences. 2016; 17(10):1691. https://doi.org/10.3390/ijms17101691
Chicago/Turabian StyleMárta, Katalin, Nelli Farkas, Imre Szabó, Anita Illés, Áron Vincze, Gabriella Pár, Patrícia Sarlós, Judit Bajor, Ákos Szűcs, József Czimmer, and et al. 2016. "Meta-Analysis of Early Nutrition: The Benefits of Enteral Feeding Compared to a Nil Per Os Diet Not Only in Severe, but Also in Mild and Moderate Acute Pancreatitis" International Journal of Molecular Sciences 17, no. 10: 1691. https://doi.org/10.3390/ijms17101691