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Open AccessArticle

Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines

by 1,2, 1 and 1,*
1
Department of Chemistry, Tsinghua University, Beijing 100084, China
2
National Engineering Laboratory for Rice and Byproduct Deep Processing, Central South University of Forestry and Technology, Changsha 410004, China
*
Author to whom correspondence should be addressed.
Academic Editor: Andreas Taubert
Int. J. Mol. Sci. 2015, 16(2), 3599-3608; https://doi.org/10.3390/ijms16023599
Received: 25 December 2014 / Accepted: 2 February 2015 / Published: 5 February 2015
(This article belongs to the Section Materials Science)
3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh2Cy)Cl. View Full-Text
Keywords: aldehydes; annulation; golden complex; propargyl amine; pyrazines aldehydes; annulation; golden complex; propargyl amine; pyrazines
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MDPI and ACS Style

Su, J.; Liu, H.; Hua, R. Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines. Int. J. Mol. Sci. 2015, 16, 3599-3608.

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