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Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity

Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland at Baltimore, Baltimore, MD 21201, USA
Author to whom correspondence should be addressed.
Academic Editor: Gary O. Rankin
Int. J. Mol. Sci. 2015, 16(1), 1484-1494;
Received: 1 October 2014 / Accepted: 30 December 2014 / Published: 9 January 2015
(This article belongs to the Special Issue Renal Toxicology—Epidemiology and Mechanisms)
PDF [871 KB, uploaded 9 January 2015]


Among the organs in which the environmental pollutant cadmium causes toxicity, the kidney has gained the most attention in recent years. Numerous studies have sought to unravel the exact pathways by which cadmium enters the renal epithelial cells and the mechanisms by which it causes toxicity in the kidney. The purpose of this review is to present the progress made on the mechanisms of cadmium transport in the kidney and the role of transporter proteins in cadmium-induced nephrotoxicity. View Full-Text
Keywords: cadmium; transporter; nephrotoxicity cadmium; transporter; nephrotoxicity

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Yang, H.; Shu, Y. Cadmium Transporters in the Kidney and Cadmium-Induced Nephrotoxicity. Int. J. Mol. Sci. 2015, 16, 1484-1494.

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