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Molecules 1998, 3(2), 44-47;

A Short and Efficient Synthesis of (R)-Phoracantholide I

Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai - 400 085, India
Author to whom correspondence should be addressed.
Received: 16 January 1998 / Accepted: 26 January 1998 / Published: 13 February 1998
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A short and efficient chemoenzymatic synthesis of the title compound has been developed. The salient features of the synthesis were i) preparation of the required chiron via a porcine pancreatic lipase (PPL) catalyzed esterification of a ω-functionalized 2-alkanol and ii) use of easily accessible and inexpensive materials/ reagents. View Full-Text
Keywords: Phoracantholide I; enantioselective synthesis; lipase catalyzed resolution Phoracantholide I; enantioselective synthesis; lipase catalyzed resolution

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Sharma, A.; Chattopadhyay, S. A Short and Efficient Synthesis of (R)-Phoracantholide I. Molecules 1998, 3, 44-47.

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