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Review

Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers

1
Department of Viticulture and Enology, Faculty of Horticulture, Mendel University in Brno, Valtická 337, 691-44 Lednice, Czech Republic
2
Centre of Experimental Medicine, Slovak Academy of Sciences, Institute of Normal and Pathological Physiology, 841-04 Bratislava, Slovakia
3
Faculty of Central European Studies, Institute for Teacher Training, Constantine the Philosopher University in Nitra, Drazovska 4, SK-949-74 Nitra, Slovakia
4
Department of Food Analysis and Chemistry, Faculty of Technology, Tomas Bata University in Zlin, Vavrečkova 275, 760-01 Zlin, Czech Republic
5
Department of Food Technology, Faculty of Agronomy, Mendel University in Brno, Zemedelska 1, 613-00 Brno, Czech Republic
*
Author to whom correspondence should be addressed.
Academic Editors: Manuela Pintado, Ezequiel Coscueta and Maria Emilia Brassesco
Molecules 2020, 25(22), 5311; https://doi.org/10.3390/molecules25225311
Received: 15 October 2020 / Revised: 11 November 2020 / Accepted: 12 November 2020 / Published: 14 November 2020
(This article belongs to the Special Issue Bioproducts for Health)
This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of “Vitis vinifera L.” seed extract reduce the level of oxidative stress and improve the overall lipid metabolism. View Full-Text
Keywords: antioxidants; cancer; cardiovascular disease; diabetes mellitus; gastrointestinal tract; grape seeds; grape skin; neuroprotective effect antioxidants; cancer; cardiovascular disease; diabetes mellitus; gastrointestinal tract; grape seeds; grape skin; neuroprotective effect
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MDPI and ACS Style

Sochorova, L.; Prusova, B.; Cebova, M.; Jurikova, T.; Mlcek, J.; Adamkova, A.; Nedomova, S.; Baron, M.; Sochor, J. Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers. Molecules 2020, 25, 5311. https://doi.org/10.3390/molecules25225311

AMA Style

Sochorova L, Prusova B, Cebova M, Jurikova T, Mlcek J, Adamkova A, Nedomova S, Baron M, Sochor J. Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers. Molecules. 2020; 25(22):5311. https://doi.org/10.3390/molecules25225311

Chicago/Turabian Style

Sochorova, Lenka, Bozena Prusova, Martina Cebova, Tunde Jurikova, Jiri Mlcek, Anna Adamkova, Sarka Nedomova, Mojmir Baron, and Jiri Sochor. 2020. "Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers" Molecules 25, no. 22: 5311. https://doi.org/10.3390/molecules25225311

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