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Molecules 2018, 23(4), 871;

A Novel Colorimetric Fluorescent Probe for SO2 and Its Application in Living Cells Imaging

School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China
Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China
Authors to whom correspondence should be addressed.
Received: 18 March 2018 / Revised: 3 April 2018 / Accepted: 6 April 2018 / Published: 10 April 2018
(This article belongs to the Section Analytical Chemistry)
PDF [12255 KB, uploaded 3 May 2018]


A novel chromenylium-based fluorescent probe was exploited for sulphur dioxide (SO2) detecting. The probe displayed a remarkable fluorescence turn-on response towards SO2 based on the nucleophilic addition reaction to the carbon-carbon double bond with 105 nm Stock shift. The probe was successfully applied for the quantification of SO2.The linear detection range was from 0–160 μM with the detection limit as low as 99.27 nM. It also exhibited high selectivity for SO2 than other reactive species and amino acids. Furthermore, cell staining experiments indicated that the probe was cell membrane permeable and could be used for high-performance imaging of SO2 in living cells. The superior properties of the probe made it highly promising for use in chemical and biological applications. View Full-Text
Keywords: fluorescent probe; SO2; colorimetric; living cell imaging fluorescent probe; SO2; colorimetric; living cell imaging

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Wu, M.-Y.; Wu, J.; Wang, Y.; Liu, Y.-H.; Yu, X.-Q. A Novel Colorimetric Fluorescent Probe for SO2 and Its Application in Living Cells Imaging. Molecules 2018, 23, 871.

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