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Molecules, Volume 17, Issue 10

October 2012 - 84 articles

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Articles (84)

  • Article
  • Open Access
36 Citations
8,112 Views
18 Pages

Bioassays Against Pinewood Nematode: Assessment of a Suitable Dilution Agent and Screening for Bioactive Essential Oils

  • Pedro Barbosa,
  • Jorge M. S. Faria,
  • Marta D. Mendes,
  • Luís Silva Dias,
  • Maria Teresa Tinoco,
  • José G. Barroso,
  • Luis G. Pedro,
  • Ana Cristina Figueiredo and
  • Manuel Mota

19 October 2012

Acetone was investigated and found to be an appropriate alternative to Triton X-100 as a solvent of essential oils in bioassays aimed to investigate their effects on pinewood nematode (Bursaphelenchus xylophilus) mortality. Therefore it was used as d...

  • Article
  • Open Access
67 Citations
7,429 Views
11 Pages

Phenolic and Lignan Glycosides from the Butanol Extract of Averrhoa carambola L. Root

  • Qingwei Wen,
  • Xing Lin,
  • Yeqi Liu,
  • Xiaohui Xu,
  • Tao Liang,
  • Ni Zheng,
  • Kintoko and
  • Renbin Huang

19 October 2012

Fifteen compounds, which included six chiral lignans and nine phenolic glycosides, were separated from the butanol fraction of Averrhoa carambola L. root and identified. All of the compounds, namely 3,4,5-trimethoxyphenol-1-O-β-D-glucopyranoside (1),...

  • Article
  • Open Access
41 Citations
9,594 Views
16 Pages

Comparison of the Phenolic Compounds, Carotenoids and Tocochromanols Content in Wheat Grain under Organic and Mineral Fertilization Regimes

  • Iwona Konopka,
  • Małgorzata Tańska,
  • Alicja Faron,
  • Arkadiusz Stępień and
  • Katarzyna Wojtkowiak

19 October 2012

A field study was performed to evaluate the effect of mineral (NPK) and organic-based fertilizers such as compost (C), manure (FYM) and meat and bone meal (MBM) on the appearance (dimensions and color) of spring wheat kernels and on the total content...

  • Article
  • Open Access
11 Citations
10,168 Views
19 Pages

Discovery and Validation of SIRT2 Inhibitors Based on Tenovin-6: Use of a 1H-NMR Method to Assess Deacetylase Activity

  • Lisa Pirrie,
  • Anna R. McCarthy,
  • Louise L. Major,
  • Vaida Morkūnaitė,
  • Asta Zubrienė,
  • Daumantas Matulis,
  • Sonia Lain,
  • Tomas Lebl and
  • Nicholas J. Westwood

18 October 2012

The search for potent and selective sirtuin inhibitors continues as chemical tools of this type are of use in helping to assign the function of this interesting class of deacetylases. Here we describe SAR studies starting from the unselective sirtuin...

  • Article
  • Open Access
9 Citations
7,242 Views
9 Pages

18 October 2012

Coupling of 2-benzylmalononitrile with aromatic diazonium salts afforded 3-phenyl-2-arylhydrazonopropanenitriles 4a,b, which were rearranged into 2-cyanoindoles 5a,b upon heating with ZnCl2 in the presence of glacial acetic acid. The produced indole...

  • Communication
  • Open Access
51 Citations
8,748 Views
9 Pages

Solvent-Free Synthesis of Modified Pectin Compounds Promoted by Microwave Irradiation

  • Enrica Calce,
  • Valeria Bugatti,
  • Vittoria Vittoria and
  • Stefania De Luca

18 October 2012

Microwave-assisted solvent-free modification of pectin was successfully accomplished, consisting in the esterification of several fatty acids by pectin alcoholic functions. The reaction was performed by simply mixing the reagents with a catalytic amo...

  • Article
  • Open Access
10 Citations
7,333 Views
9 Pages

Identification of Fungicidal 2,6-Disubstituted Quinolines with Activity against Candida Biofilms

  • Nicolas Delattin,
  • Dorothée Bardiot,
  • Arnaud Marchand,
  • Patrick Chaltin,
  • Katrijn De Brucker,
  • Bruno P. A. Cammue and
  • Karin Thevissen

18 October 2012

We have identified two subseries of 2,6-disubstituted quinolines, consisting of 6-amide and 6-urea derivatives, which are characterized by fungicidal activity against Candida albicans with minimal fungicidal concentration (MFC) values < 15 µM. The 6-...

  • Communication
  • Open Access
31 Citations
9,550 Views
10 Pages

First Example of a Lipophilic Porphyrin-Cardanol Hybrid Embedded in a Cardanol-Based Micellar Nanodispersion

  • Ermelinda Bloise,
  • Luigi Carbone,
  • Giuseppe Colafemmina,
  • Lucia D’Accolti,
  • Selma Elaine Mazzetto,
  • Giuseppe Vasapollo and
  • Giuseppe Mele

18 October 2012

Cardanol is a natural and renewable organic raw material obtained as the major chemical component by vacuum distillation of cashew nut shell liquid. In this work a new sustainable procedure for producing cardanol-based micellar nanodispersions having...

  • Article
  • Open Access
52 Citations
9,426 Views
14 Pages

Design, Synthesis and in Vivo Anti-inflammatory Activities of 2,4-Diaryl-5-4H-imidazolone Derivatives

  • Moustafa El-Araby,
  • Abdelsattar Omar,
  • Hassanein H. Hassanein,
  • Abdel-Ghany H. El-Helby and
  • Asharf A. Abdel-Rahman

18 October 2012

A series of 2,4-diaryl-5(4H)-imidazolones were prepared and evaluated for their anti-inflammatory activities. Some selected 2,4-diaryl-5(4H)-imidazolones exhibited excellent anti-inflammatory activity in the carrageenan-induced rat paw edema model. S...

  • Review
  • Open Access
439 Citations
25,549 Views
11 Pages

Antimicrobial Peptides for Therapeutic Applications: A Review

  • Min-Duk Seo,
  • Hyung-Sik Won,
  • Ji-Hun Kim,
  • Tsogbadrakh Mishig-Ochir and
  • Bong-Jin Lee

18 October 2012

Antimicrobial peptides (AMPs) have been considered as potential therapeutic sources of future antibiotics because of their broad-spectrum activities and different mechanisms of action compared to conventional antibiotics. Although AMPs possess consid...

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Molecules - ISSN 1420-3049