Dynamic Nano-Biomaterials in Tissue Regeneration and Cancer Therapies

Topic Information

Dear Colleagues,

In recent years, the trends in dynamic nanomaterials' response to cell engineering have led to novel tissue remodelling approaches to better understand cell regulatory mechanisms and related applications. Specifically, the combination of novel biomaterial-associated systems and techniques in regenerative tissue approaches allows for us to monitor the cellular response during material applications. Moreover, the tissue-specific micro-environment surrounding cells is dynamic rather than static. Taking advantage of various biomaterials and cell-specific modulatory functions, we aimed to focus this Special Issue on using dynamic nanomaterials in tissue remodelling and drug delivery functions for various biomedical applications. Ultimately, our approach invites papers in biomaterials modulation of cell fate decision/drug delivery using dynamically engineered biomaterials, giving a novel conceptual approach to regenerative medicine, stem cell therapy, immune modulation, and cancer therapies. Our vision is to provide a suitable platform for novel biological insights into biomaterials' role in cell engineering, cell–material interactions, extracellular matrix modulation, stem cell biology, novel drug delivery, stimuli-responsive drug delivery, and cancer-targeted delivery therapies. This Special Issue will also present the importance of advanced nanomaterials and functional material platforms for cell, nano, healthcare, and materials technologists looking to publish papers related to nanoengineering attributes. Finally, this Special Issue will examine the emerging aspects of dynamic biomaterials and their advanced applications, focusing on tissue engineering and drug delivery.

Dr. Ramar Thangam
Dr. Heemin Kang
Dr. Bibin G. Anand
Dr. Ramachandran Vijayan
Dr. Venugopal Krishnan
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Bioengineering bioengineering	3.8	4.0	2014	16.4 Days	CHF 2700
Biomolecules biomolecules	4.8	9.4	2011	18.4 Days	CHF 2700
Cancers cancers	4.5	8.0	2009	17.4 Days	CHF 2900
Diseases diseases	2.9	0.8	2013	21.4 Days	CHF 1800
Nanomaterials nanomaterials	4.4	8.5	2010	14.1 Days	CHF 2400
Pharmaceutics pharmaceutics	4.9	7.9	2009	15.5 Days	CHF 2900

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Published Papers (1 paper)

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All Bioengineering Biomolecules Cancers Diseases Nanomaterials Pharmaceutics

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18 pages, 966 KiB  

Open AccessReview

Personalised Medicine and the Potential Role of Electrospinning for Targeted Immunotherapeutics in Head and Neck Cancer

by Connor H. O’Meara, Thanh Vinh Nguyen, Zuhayr Jafri, Michael Boyer, David C. Shonka, Jr. and Levon M. Khachigian

Nanomaterials 2024, 14(1), 6; https://doi.org/10.3390/nano14010006 - 19 Dec 2023

Cited by 2 | Viewed by 1802

Abstract

Advanced head and neck cancer (HNC) is functionally and aesthetically destructive, and despite significant advances in therapy, overall survival is poor, financial toxicity is high, and treatment commonly exacerbates tissue damage. Although response and durability concerns remain, antibody-based immunotherapies have heralded a paradigm [...] Read more.

Advanced head and neck cancer (HNC) is functionally and aesthetically destructive, and despite significant advances in therapy, overall survival is poor, financial toxicity is high, and treatment commonly exacerbates tissue damage. Although response and durability concerns remain, antibody-based immunotherapies have heralded a paradigm shift in systemic treatment. To overcome limitations associated with antibody-based immunotherapies, exploration into de novo and repurposed small molecule immunotherapies is expanding at a rapid rate. Small molecule immunotherapies also have the capacity for chelation to biodegradable, bioadherent, electrospun scaffolds. This article focuses on the novel concept of targeted, sustained release immunotherapies and their potential to improve outcomes in poorly accessible and risk for positive margin HNC cases. Full article

(This article belongs to the Topic Dynamic Nano-Biomaterials in Tissue Regeneration and Cancer Therapies)

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