Bridging Ecosystem Contamination and One Health: Integrating Environmental, Animal, and Human Risk Assessment

Dear Colleagues,

Environmental contamination remains one of the most pressing global threats, with pollutants such as microplastics, heavy metals, endocrine disruptors, and per- and polyfluoroalkyl substances (PFAS) increasingly affecting ecosystems and public health. This Topic aims to promote interdisciplinary research integrating environmental sciences, veterinary and medical toxicology, and public health under the One Health approach. The collection will highlight studies elucidating how environmental pollutants influence health outcomes across species, biomolecular mechanisms underlying toxicity, and strategies for sustainable mitigation and policy translation. Understanding environmental contamination through the One Health framework is essential for assessing risks that simultaneously affect wildlife, domestic animals, and human populations. Despite increasing awareness, research often remains siloed. This Topic bridges these domains by encouraging transdisciplinary contributions exploring the following: molecular and physiological effects of contaminants in sentinel and model species; biomarkers and early-warning indicators for cross-species health assessment; environmental monitoring and ecological risk modeling aligned with One Health principles; and innovative remediation and prevention strategies informed by integrated risk analysis. By fostering holistic perspectives, this Topic supports the implementation of sustainable environmental policies and health protection strategies that reflect the interconnectedness of all living systems.

Dr. Marika Cordaro
Dr. Davide Di Paola
Topic Editors