Search Results (379)

Air pollution from lignite combustion represents a major environmental and public health concern, particularly for cardiovascular disease. This study investigated the relationship between ambient air pollution and hospital admissions for Acute Coronary Syndromes (ACS) and Atrial Fibrillation (AF) in Western Macedonia, Greece—a region historically dominated by lignite mining and power generation. Air quality data for PM₁₀, SO₂, and NO_x from 2011–2014 and 2021 were analyzed alongside hospital admission records from four regional hospitals (Kozani, Ptolemaida, Florina, Grevena). Spatial analyses revealed significantly higher pollutant concentrations and cardiovascular admissions in high-exposure areas near power plants compared with the control area. Temporal analyses demonstrated a pronounced decline in pollutant levels between 2014 and 2021, coinciding with lignite phase-out and accompanied by a marked reduction in ACS and AF hospitalizations, particularly in the high-exposure areas of Ptolemaida and Florina. Correlation analyses indicated modest but significant positive associations between monthly pollutant concentrations and cardiovascular admissions. These findings provide real-world evidence that reductions in air pollution following lignite decommissioning were associated with improved cardiovascular outcomes. The study underscores the medical importance of air quality improvement and highlights emission reduction as a critical strategy for cardiovascular disease prevention in transitioning energy regions. Full article

This study evaluates the feasibility of establishing a new strawberry cultivation zone in the Region of Florina, Northern Greece, as a strategy to support rural revitalization and agricultural diversification. Day-neutral strawberry genotypes were cultivated under net-house conditions at the University of Western Macedonia and assessed for physiological traits (SPAD index, chlorophyll fluorescence) and fruit quality (weight, color, firmness, °Brix, titratable acidity); while postharvest behavior was evaluated after seven days of cold storage. Statistical analysis identified genotypes with superior physiological performance and storability. Preliminary economic analysis suggests that their adoption could increase growers’ income by 20–30% compared to conventional varieties. The findings support the development of a strawberry production zone in Florina, with broader implications for sustainable agricultural intensification and rural development in underutilized European regions. Full article

This study investigates thermal stress and energy-related anxiety as lived, multidimensional manifestations of energy poverty in Western Macedonia, Greece, a coal phase-out region undergoing just transition. Using a 261-household survey, we construct a thermal stress index from four Likert-type items capturing seasonal thermal adequacy, energy anxiety, and restricted use of rooms. High thermal stress is defined as the upper quartile of the index. Descriptive results indicate that high thermal stress affects 27.2% of households, exceeding a 20% threshold, while energy-related anxiety and restricted room use are widespread. We then estimate logistic regression models to examine whether vulnerability characteristics (disability-related thermal/electric needs, single parenthood, dependent children, benefit receipt, elderly presence), financial stress indicators (arrears, energy debt, frequent forced reductions in consumption), and socio-economic controls (income, employment, tenure, age, gender) predict high thermal stress. Adjusted models show that vulnerability markers do not retain statistically independent associations once controls are included. In contrast, tenure and energy-related financial stress are significantly associated with the probability of high thermal stress. The findings highlight the importance of measurement choices and suggest that experiential indicators capture energy-poverty dynamics that are not reducible to income-based targeting, with implications for just-transition policy design and energy justice. Full article

Western Macedonia, the leading power-producing region in Greece, has long depended on thermoelectric plants and lignite mining. To reach climate neutrality by 2050, Greece is undergoing a delignitization process aiming to shut down all lignite plants. This structural reconstruction of the energy model will mainly affect society, the economy, the environment, and agriculture. Strengthening efforts to support lignite-dependent areas are essential for this transition. Bioeconomy could be one of the main pillars for the post-lignite era in the Western Macedonia Region (WMR). This paper explores the gender dimension in the adoption of bioeconomy practices and innovativeness among farmers in the Region of Western Macedonia. Based on 331 structured questionnaires and a Two-Step Cluster Analysis, the research identifies five farmer clusters and then correlates the clusters with Rogers’s theory of diffusion of innovations. The findings identify a dynamic group of young female farmers leading the diffusion of innovation, emphasizing their role in promoting sustainable agricultural transitions and the need for gender-responsive policies in regional bioeconomy strategies. Full article

An integrated early warning system (EWS) for compound coastal and fluvial flooding is developed for Pyrgos, Western Greece, where low-lying geomorphology and past storm events highlight the need for rapid, impact-based forecasting. The methodology couples historical and climate-informed metocean and river discharge datasets within a numerical modeling framework consisting of a mild-slope wave model, the CSHORE coastal profile model, and HEC-RAS 2D inundation simulations. A weighted K-Means clustering approach is used to generate representative extreme scenarios, yielding more than 4000 coupled simulations that train and validate Artificial Neural Networks (ANNs). The optimal feed-forward ANN accurately predicts spatially distributed flood depths across the HEC-RAS grid using only offshore wave characteristics, water level, and river discharge as inputs, reducing computation time from hours to seconds. Blind tests demonstrate close agreement with full numerical simulations, with average differences typically below 5% and minor deviations confined to negligible water depths. These results confirm the ANN’s capability to emulate complex compound flooding dynamics with high computational efficiency. Deployed as a web application (EWS_CoCoFlood), the system provides actionable, near-real-time inundation forecasts to support local civil protection authorities. The framework is modular and scalable, enabling future integration of urban and rainfall-induced flooding processes and coastal morphological change. Full article

Blood culture remains the gold standard for identifying bloodstream infections caused by bacteria and fungi. Isolation of the culprit microorganism onto agar plates also facilitates antimicrobial susceptibility testing. The purpose of this study was to determine the contamination rates, pathogen profile, and antimicrobial resistance in a secondary healthcare setting in a two-year timeframe. In this study, data regarding blood cultures of the years 2023 and 2024 were retrospectively analyzed to address the above questions. Blood cultures were incubated for seven days before being discarded as negative. The percentage of positive blood cultures for both years was 14.3%. Most positive cultures contained Gram-positive cocci, with a prevalence of coagulase-negative Staphylococci. In descending order, 72.72% were coagulase-negative Staphylococci, 15.15% were Staphylococcus aureus, and 12.12% were Streptococci. One strain of S. aureus was methicillin-resistant (MRSA), and one strain of Enterococcus faecium was vancomycin-resistant (VRE). Of the Gram-negative rods, 78.3% were Enterobacterales. Of these, Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis were the top pathogens. The remainder comprised eight strains of Pseudomonas aeruginosa, four strains of Acinetobacter baumannii (one pandrug-resistant), three strains of Stenotrophomonas maltophilia, one strain of Sphingomonas paucimobilis, and one strain of Campylobacter jejuni. The isolated fungi comprised Candida parapsilosis, Candida glabrata, and Candida tropicalis. Of the isolated Escherichia coli strains, 39.5% were resistant to ciprofloxacin regardless of origin (outpatient or hospitalized patients). Outpatient samples were taken in a Hemodialysis Unit that collaborates with our laboratory, obtained from patients with fever or other signs of infection. Distinguishing true bacteremia from contamination remains challenging. The contamination rate in our study was quite high at 5.3%. Since there is no dedicated phlebotomy team in our healthcare setting, in light of our results, educational courses have been conducted to demonstrate the best practices for sample collection. Full article

The epidemiology of central nervous system (CNS) infections caused by herpesviruses varies with host factors and geographic distribution. Timely diagnosis and therapeutic intervention are life-saving. This study investigated the epidemiology of herpesvirus CNS infections in Western Greece, compared clinical and laboratory findings with international data and evaluated an internal laboratory algorithm for cerebrospinal fluid (CSF) molecular testing criteria. During the study period, 940 of 4300 CSF samples met eligibility criteria for RT-PCR detection of herpes simplex virus (HSV-1, HSV-2) and varicella zoster virus (VZV). Of these, 53 (5.63%) were positive: 37 VZV, 9 HSV-1, and 7 HSV-2. HSV-2 cases occurred in younger patients (median age 41) and had the highest CSF white blood cells (WBC) counts (231/mm³), followed by VZV (125/mm³) and HSV-1 (26/mm³). CSF protein was higher in HSV-2 infections. Magnetic resonance imaging (MRI) was the most sensitive imaging modality for detecting CNS inflammation. These results indicate VZV as the predominant herpesvirus in this region, underscoring the need for high clinical suspicion in older patients and timely molecular diagnosis. Full article

Air pollution constitutes a major environmental determinant of cardiovascular morbidity and mortality worldwide. Western Macedonia, Greece, has historically hosted the largest lignite mining and combustion complex in Southeastern Europe, creating a unique exposure environment. This study investigates the relationship between air pollutant concentrations and cardiovascular hospital admissions over a ten-year period in this lignite-dependent region. Daily concentrations of particulate matter (PM₁₀), sulfur dioxide (SO₂), nitric oxide (NO), nitrogen dioxide (NO₂), and total nitrogen oxides (NO_x) were collected from regional monitoring stations for the winters of 2011–2021, while corresponding daily cardiovascular hospital admissions were obtained from the regional hospitals of Kozani, Ptolemaida, Florina, and Grevena. Spearman’s rank correlations and Friedman’s non-parametric tests were applied to assess temporal and spatial associations between pollutant levels and hospital admissions. A marked decline in air pollutant concentrations, particularly PM₁₀ and SO₂, was observed across the decade, coinciding with a significant reduction in cardiovascular hospitalizations. Specifically, PM₁₀ levels fell from ~75 μg/m³ to ~30 μg/m³ in Florina and from ~53 μg/m³ to ~11 μg/m³ in Ptolemaida, while SO₂ concentrations decreased by more than 90% across all sites. Cardiovascular admissions declined by 20–40% depending on the region over the same period. Significant but modest positive correlations were detected between PM₁₀ and admissions in Florina (ρ = 0.138, p = 0.017), SO₂ in Ptolemaida (ρ = 0.122, p = 0.034), and NO₂ in Kozani (ρ = 0.115, p = 0.045). Regions located near lignite combustion sites consistently exhibited higher pollutant levels and hospitalization rates. The study provides quantitative evidence linking air pollution from lignite combustion to adverse cardiovascular outcomes. The parallel decline in both pollution levels and hospital admissions underscores the cardiovascular benefits of emission reduction and the ongoing energy transition in Western Macedonia. Continuous air quality monitoring and preventive public health measures remain essential for safeguarding cardiovascular health in former coal-based regions. Full article

Background/Objectives: Vitamin D in its active form, 1,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃], plays a critical role in immune regulation, gut barrier function, and systemic inflammation. Its deficiency is frequent in Inflammatory Bowel Disease (IBD), but the clinical implications remain uncertain. The aim of the study is to assess the prevalence of vitamin D deficiency in a well-characterized IBD cohort in Western Greece, and explore its associations with clinical features, laboratory biomarkers, and treatment intensity. Methods: In this cross-sectional study, 184 consecutive, well-characterized IBD outpatients followed at a tertiary referral center in Western Greece underwent clinical evaluation and laboratory testing between January 2023 and December 2024. Vitamin D is determined by measuring 25-hydroxyvitamin D [25(OH)D], which reflects the body’s vitamin D stores due to its longer half-life compared with the biologically active form. Deficiency was defined as serum 25(OH)D < 20 ng/mL. Associations with disease type, clinical and laboratory biomarkers, severity indices, and treatment were analyzed using multivariate logistic regression. Results: Vitamin D deficiency was identified in 67 patients (36.4%). Although unrelated to disease type, hospitalization, surgery, or disease activity indices, deficiency correlated with systemic inflammation, nutrition/metabolic markers, and treatment intensity. More specifically, vitamin D-deficient patients exhibited higher platelet counts (p = 0.005) and erythrocyte sedimentation rate (ESR) (p = 0.014), lower hemoglobin (p = 0.005), albumin (p = 0.011), and serum glutamic-oxaloacetic transaminase (SGOT) (p = 0.009) levels and more frequent use of biologic therapy (p = 0.009). In multivariate analysis, vitamin D deficiency remained independently associated with biologic therapy (aOR = 0.374; 95% CI: 0.148–0.946), platelet count (aOR = 0.996, 95% CI: 0.992–0.999), and SGOT (aOR = 1.05, 95% CI: 1.00–1.10), indicating consistent links between vitamin D deficiency and treatment intensity, systemic inflammation, and nutritional or metabolic status. Conclusions: Vitamin D deficiency is common among IBD patients and independently associates with systemic inflammation, metabolic impairment, and intensified treatment requirement, supporting its potential role as a marker of disease burden. Full article

Surveys and excavations carried out between 2004 and 2019 around the Vlach town of Samarina, in the Pindos Mountains of Western Macedonia (Greece), have yielded potsherds that can be attributed to different historical periods. The data collected so far suggest a long human presence in this region of the northern Pindos spanning from the Middle Pleistocene to the late Middle Ages. The ceramic fragments from the Historical Camp (HC), Kirkouri (KRK), the Holy Cross Church (SMC), Mt. Anitsa (Anitsa), Avgo (VGO), the Mirminda Pass (VLC), Mt. Vasilitsa (VSL), and the saddle between Mts. Bogdhani and Gurguliu have been studied in detail. Despite their fragmentary state, a database has been created with the morphological and typological characteristics of the potsherds and the sites from which they were retrieved. Coarse and fine ware potsherds have been identified. According to their manufacturing characteristics, they can be attributed to different Roman and medieval periods. A diassarion of the Larissa mint shows that connections between the mountain highlands and the lowlands were already active during the period of Emperor Augustus. The Samarina potsherds are probably related to the movements of Vlach shepherds, who spent long periods in these mountains with their flocks. This impression is confirmed by the presence of one vessel wall fragment which was directly in contact with fire and a few small vessel bases. The presence of ceramic vases is closely linked to the transportation of primary or secondary food supplies in a pre-cooked form or as liquids. We know that Vlach shepherds, as many other groups of Eurasian shepherds, never manufactured ceramic vessels even in their villages. Instead, they used different types of wooden and metal containers for cooking, drinking, and other tasks associated with pastoral activities, such as keeping milk and making cheese and butter, for example. Following these observations, our aim has been to define the vessel types used by the Vlach shepherds, which exhibit some kind of uniformity from the Roman to the Middle Ages. Full article

The Eastern Mediterranean is a rapidly warming climate change hotspot where heat and air pollution increasingly interact to affect human health. This study quantifies the mortality burden attributed to the synergistic effects of thermal stress and air pollution in Thessaloniki, Greece. Daily mortality data (2001–2019) were analyzed together with pollutant concentrations (PM10, NO₂, O₃) and the modified Physiologically Equivalent Temperature (mPET) using a hierarchical Generalized Additive Model with Distributed Lag Non-Linear terms to capture combined, lagged, and age-specific responses. A refined, count-independent definition of the Attributable Fraction (AF) was introduced to improve stability in small strata. The results show that heat and pollution act synergistically, explaining on average 20–30% of daily mortality during severe co-occurrence events. Seniors were most affected during hot, polluted summers (AF ≈ 27%), while adults showed higher burdens during cold, polluted winters (AF ≈ 30%). Intra-urban analyses revealed stronger simultaneous effects in the western, more industrial districts, reflecting combined environmental and socioeconomic vulnerability. The findings demonstrate that temperature extremes amplify pollution-related mortality and underline the need to integrate air quality and bioclimatic indicators into early warning and adaptation systems in Eastern Mediterranean cities. Full article

Flash droughts—characterized by their sudden development, severity, and short duration—impose considerable challenges on the soil–water complex of agricultural systems, especially under the Mediterranean climate. Though gaining increasing global significance, Mediterranean flash droughts are still understudied. This study examines the spatiotemporal variability of flash droughts in Greece for the period 1990–2024 using 5-day (pentad) ERA5-Land root-zone soil moisture (0–100 cm) at 0.25° resolution. A percentile-threshold approach detected flash drought events, and their main features—including frequency, duration, magnitude, intensity, decline rate, recovery rate, and recovery duration—were evaluated at the annual and seasonal levels. Findings indicate that Central Greece and Thessaly face the highest frequency and longevity of flash droughts, while Western Greece and Peloponnese and Western Macedonia are characterized by rapid development but intense recovery. An innovative empirical classification framework founded on decline and recovery rates indicated that Mild Fast Recovery events prevail in northern and central Greece, while Intense but Recovering events dominate in western and southern Greece. These results offer new perspectives on how flash droughts impact soil–water availability and agricultural resilience, providing a data-driven platform to aid sustainable water management, early warning systems, and adaptation strategies for Mediterranean agriculture in conditions of climate variability. Full article

The latest climate change predictions indicate that the sea level will accelerate in the coming decades as a direct consequence of global warming. This is expected to seriously threaten low-lying coastal areas worldwide, resulting in severe coastal flooding with significant socio-economic impacts, leading to the loss of coastal settlements, exploitable land, and natural ecosystems. The main objective of this study is to provide a first-order preliminary estimation of potential inundation extents along the northern coastline of the Amvrakikos Gulf, a deltaic complex formed by the Arachthos, Louros, and Vouvos rivers in Western Greece, resulting from long-term sea-level rise induced by climate change, using the integrated Bathtub and Hydraulic Connectivity (HC) inundation method. A 2 m resolution Digital Elevation Model (DEM) was used, along with local long-term sea-level projections, for the years 2050 and 2100. Additionally, subsidence rates due to the compaction of deltaic sediments were taken into account. To assess the area’s proneness to inundation caused or enhanced by sea-level rise, the extent of each land cover type, the Natura 2000 Network protected area, the settlements, the total length of the road network, and the cultural assets located within the inundation zones under each climate change scenario were considered. The analysis revealed that under the optimistic SSP1-1.9 scenario of the Intergovernmental Panel on Climate Change (IPCC), areas of 40.81 km² (min 20.34 km², max 63.55 km²) and 69.10 km² (min 41.75 km², max 88.02 km²) could potentially be inundated by 2050 and 2100, respectively. Under the pessimistic SSP5-8.5 scenario, the inundation zone expands to 42.56 km² (min 37.05 km², max 66.31 km²) by 2050 and 84.55 km² (min 67.54 km², max 116.86 km²) by 2100, affecting a significant portion of ecologically valuable wetlands and water bodies within the Natura 2000 protected area. Specifically, the inundated Natura 2000 area is projected to range from 37.77 km² (min 20.30 km², max 46.82 km²) by 2050 to 50.74 km² (min 38.71 km², max 62.84 km²) by 2100 under the SSP1-1.9 scenario, and from 39.34 km² (min 34.53 km², max 49.09 km²) by 2050 to 60.48 km² (min 49.73 km², max 82.5 km²) by 2100 under the SSP5-8.5 scenario. Four settlements with a total population of approximately 800 people, as well as 32 economic facilities most of which operate in the secondary and tertiary sectors and are small to medium-sized economic units, such as olive mills, farms, gas stations, spare parts stores, construction companies, and food service establishments, are expected to experience significant exposure to coastal flooding and operational disruptions in the near future due to sea-level rise. Full article

Background: People experiencing homelessness (PEH) face significant health disparities and systemic barriers to healthcare, elevating their risk for cancer and other chronic diseases. To tackle PEHs’ challenges in accessing cancer preventive care, the CANCERLESS project implemented the Health Navigator Model (HNM)—a person-centered intervention that utilizes trained Health Navigators to provide tailored support and facilitate service access. Recognizing housing as a key determinant of health, this analysis assessed changes in housing status associated with participation in the HNM among CANCERLESS participants in Austria, Greece, Spain, and the UK. Methods: This was a secondary analysis of cross-national data collected during a single-arm interventional study. Of 652 enrolled PEH, 277 (42.5%) completed the HNM intervention follow-up and were included in the analysis. Changes in housing status from baseline to follow-up were categorized using the European Typology of Homelessness and Housing Exclusion (ETHOS) and treated as an ordered outcome. Descriptive statistics were complemented by a cumulative link mixed model with a participant random intercept to estimate the association between time (follow-up vs. baseline) and housing transitions among completers, adjusting for age, residence/legal status, and daily smoking. Results: Participants had a mean age of 47.4 (SD 13.8), primarily identified as male (64.1%), reported upper secondary education (33.9%), and were from Western European countries (39.7%), with varying housing situations. Among intervention completers, time (follow-up vs. baseline) was associated with higher odds of being in a higher ETHOS category (OR = 1.49, 95% CI = 1.02–2.20, p = 0.042), consistent with a modest improvement in housing status. Larger estimates were observed among migrants without legal documents (OR = 24.13, 95% CI = 6.41–90.89, p < 0.001), while daily smoking was associated with lower odds (OR = 0.33, 95% CI = 0.11–0.96, p = 0.041); other residence status categories were not statistically significant. Conclusions: Suggesting that tailored, navigation-based models, such as the HNM, may be linked to improved housing stability for PEH, these findings can inform piloting and context-aligned integration of the HNM within public health strategies as an alternative approach to address the complex, interconnected health and social needs of PEH. However, the lack of a comparison group and high attrition limit the results’ conclusiveness, and future evaluations should aim to include assessments of housing-associated contextual factors. Full article

This study presents the first comprehensive IUCN-based assessment for all 88 Limonium species occurring in Greece, aiming to close a critical conservation gap for this highly diverse and important genus in the country. To identify patterns of extinction risk, we applied the IUCN Red List Categories and Criteria, integrating data on endemism, ploidy, and anthropogenic threats. Moreover, we employed spatial analysis to identify conservation hotspots, and we statistically analyzed how threat status changes across geographic space. Our results show that 51 species (58.0%) are threatened, with endemics (62.3%) exhibiting a significantly higher risk than non-endemics. A greater proportion of diploid species were also found to be threatened compared to their polyploid counterparts. Longitude was identified as a key spatial predictor of threat, with risk concentrated in southern and western coastal zones. The most prevalent threats are coastal development (56.9% of threatened species) and invasive species (33.3%). This work provides a vital baseline for Limonium conservation, highlighting the urgent need for a dual conservation strategy that combines efficient in situ actions with ex situ measures for the most imperiled species. Full article