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Review

1 Citations

4,936 Views

12 Pages

Deep Brain Stimulation for Major Depression and Obsessive-Compulsive Disorder—Discontinuation of Ongoing Stimulation

Hannah M. Kilian,
Bettina H. Bewernick,
Margaretha Klein,
Dora M. Meyer and ,
Susanne Spanier,
Peter C. Reinacher,
Volker A. Coenen and
Thomas E. Schlaepfer
+ 3 authors+ 0 author

Psych2020, 2(3), 174-185;https://doi.org/10.3390/psych2030015

13 August 2020

Deep brain stimulation (DBS) is currently under research for the treatment of psychiatric disorders, e.g., obsessive-compulsive disorder (OCD) and treatment-resistant depression (TRD). Since the application of DBS in psychiatry has been in use for ab...

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Perspective

15 Citations

4,724 Views

18 Pages

“The Heart Asks Pleasure First”—Conceptualizing Psychiatric Diseases as MAINTENANCE Network Dysfunctions through Insights from slMFB DBS in Depression and Obsessive–Compulsive Disorder

Volker A. Coenen,
Thomas E. Schlaepfer,
Bastian E. A. Sajonz,
Peter C. Reinacher and ,
Máté D. Döbrössy and
Marco Reisert
+ 1 author+ 0 author

Brain Sci.2022, 12(4), 438;https://doi.org/10.3390/brainsci12040438

25 March 2022

More than a decade ago, deep brain stimulation (DBS) of the superolateral medial forebrain bundle (slMFB), as part of the greater MFB system, had been proposed as a putative yet experimental treatment strategy for therapy refractory depression (TRD)...

(This article belongs to the Special Issue Advanced Research on Dopaminergic Neurons and Their Role in Depression)

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Article

1 Citations

3,010 Views

20 Pages

In Search for a Pathogenesis of Major Depression and Suicide—A Joint Investigation of Dopamine and Fiber Tract Anatomy Focusing on the Human Ventral Mesencephalic Tegmentum: Description of a Workflow

Jana M. Zielinski,
Marco Reisert,
Bastian E. A. Sajonz,
Shi Jia Teo and ,
Annette Thierauf-Emberger,
Johanna Wessolleck,
Maximilian Frosch,
Björn Spittau,
Jochen Leupold and
Volker A. Coenen
+ 6 authors+ 1 author

Brain Sci.2024, 14(7), 723;https://doi.org/10.3390/brainsci14070723

18 July 2024

Major depressive disorder (MDD) is prevalent with a high subjective and socio-economic burden. Despite the effectiveness of classical treatment methods, 20–30% of patients stay treatment-resistant. Deep Brain Stimulation of the superolateral br...

(This article belongs to the Section Neuropsychiatry)

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