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36 Results Found

  • Article
  • Open Access
3,442 Views
14 Pages

BRM: From Skin-Reducing Mastectomy to the New Concept of Breast Reshaping Mastectomy

  • Valerio Lorenzano,
  • Andrea Vittorio Emanuele Lisa,
  • Valeriano Vinci,
  • Benedetta Agnelli,
  • Alessia Lozito,
  • Marco Klinger,
  • Alessandro Mela,
  • Martina Caruso and
  • Francesco Klinger

18 February 2025

Background: Macromastia is a well-known issue in breast reconstruction. Skin-reducing mastectomy (SRM) was introduced as a skin-sparing mastectomy that utilizes a skin reduction pattern similar to breast reduction or breast lift surgery, specifically...

  • Case Report
  • Open Access
4 Citations
3,742 Views
9 Pages

Skin-Reducing Mastectomy and Immediate Reconstruction for a Large Recurrent Borderline Phyllodes Tumor

  • Daciana Grujic,
  • Horia Cristian,
  • Teodora Hoinoiu,
  • Codruta Diana Miclauș,
  • Simona Cerbu,
  • Ljubisa Grujic and
  • Cristina Oprean

29 January 2021

Background: Large recurrent phyllodes breast tumors are often malignant. Therefore, when taking the surgical decision, a simple mastectomy and immediate reconstruction must be considered. Case presentation: The patient, aged 40 years, with a benign p...

  • Article
  • Open Access
1,687 Views
10 Pages

Comparative Efficacy of Classic Versus Horizontal Incision Techniques in Skin-Reducing Mastectomy: A Single Center Retrospective Analysis

  • Andrea Vittorio Emanuele Lisa,
  • Alessandro Mela,
  • Sergio Miranda,
  • Mario Alessandri Bonetti,
  • Manuela Bottoni,
  • Mattia Intra,
  • Eleonora Pagan,
  • Vincenzo Bagnardi and
  • Mario Rietjens

21 October 2024

Background: The reconstruction of large breasts carries a heightened risk profile. While skin-reducing mastectomy (SRM) techniques facilitate the correction of breast ptosis, they are frequently associated with a high incidence of vascular complicati...

  • Article
  • Open Access
19 Citations
2,678 Views
10 Pages

Controlateral Symmetrisation in SRM for Breast Cancer: Now or Then? Immediate versus Delayed Symmetrisation in a Two-Stage Breast Reconstruction

  • Donato Casella,
  • Daniele Fusario,
  • Dario Cassetti,
  • Anna Lisa Pesce,
  • Alessandro De Luca,
  • Maristella Guerra,
  • Roberto Cuomo,
  • Diego Ribuffo,
  • Alessandro Neri and
  • Marco Marcasciano

30 November 2022

Introduction: The timing of contralateral symmetrisation in patients with large and ptotic breasts undergoing a unilateral skin-reducing mastectomy (SRM) is one of the most debated topics in the reconstructive field. There is no evidence to support t...

  • Article
  • Open Access
1 Citations
1,101 Views
12 Pages

Postoperative Outcomes of One-Step Implant-Based Breast and Ovarian Surgery in High-Penetrance Gene Mutation: A Single-Center Experience

  • Buse Irem Koc,
  • Sevket Barıs Morkavuk,
  • Simay Akyuz,
  • Guzin Aygun,
  • Ozhan Ozdemir and
  • Mehmet Ali Gulcelik

7 March 2025

Background/Objectives: This study was designed to evaluate skin-sparing mastectomy with implant reconstruction complication rates in patients operated on due to high penetrant gene profile. All patients went to skin-sparing mastectomy with implant re...

  • Article
  • Open Access
6 Citations
4,622 Views
11 Pages

26 September 2022

Introduction of skin-sparing mastectomy (SSM) led to a paradigm shift in breast reconstruction. Primary reconstructions have become the therapy of choice. At the same time, immediate autologous reconstructions are oncologically safe and aesthetically...

  • Article
  • Open Access
3 Citations
2,062 Views
12 Pages

Oncological Safety of Prepectoral Implant-Based Breast Reconstruction After Conservative Mastectomy: Insights from 842 Consecutive Breast Cancer Patients

  • Lorenzo Scardina,
  • Alba Di Leone,
  • Alejandro Martin Sanchez,
  • Cristina Accetta,
  • Liliana Barone Adesi,
  • Ersilia Biondi,
  • Beatrice Carnassale,
  • Sabatino D’Archi,
  • Flavia De Lauretis and
  • Gianluca Franceschini
  • + 10 authors

8 March 2025

Background: Implant-based breast reconstruction (IBBR) following conservative mastectomy is the most common approach for women undergoing breast cancer surgery. The aim of this study was to compare the oncological outcomes of conservative mastectomy...

  • Case Report
  • Open Access
10 Citations
3,906 Views
8 Pages

25 July 2022

The use of acellular dermal matrix (ADM) implants has enhanced breast reconstruction. ADM is a biotechnologically designed human tissue of bovine or porcine origin in which tissue processing removes cellular antigens. In this case report, we describe...

  • Article
  • Open Access
345 Views
13 Pages

Post-Operative Complications Do Not Influence Time to Adjuvant Treatment in Breast Cancer Patients Undergoing Implant-Based Reconstructions: Pre-Pectoral Versus Sub-Pectoral

  • Gianluca Vanni,
  • Marco Pellicciaro,
  • Marco Materazzo,
  • Alice Bertolo,
  • Amir Sadri,
  • Elisa Campanella,
  • Denisa Eskiu,
  • Ilaria Portarena,
  • Benedetto Longo and
  • Oreste Claudio Buonomo
  • + 1 author

29 December 2025

Background: Immediate breast reconstruction after mastectomy has progressively shifted toward less invasive approaches. The pre-pectoral approach, avoiding muscle dissection, may reduce post-operative pain, surgical trauma, and recovery time. However...

  • Article
  • Open Access
9 Citations
3,535 Views
12 Pages

A Retrospective Study Assessing the Outcomes of Immediate Prepectoral and Subpectoral Implant and Mesh-Based Breast Reconstruction

  • Thomas Wow,
  • Agnieszka Kolacinska-Wow,
  • Mateusz Wichtowski,
  • Katarzyna Boguszewska-Byczkiewicz,
  • Zuzanna Nowicka,
  • Katarzyna Ploszka,
  • Karolina Pieszko and
  • Dawid Murawa

29 June 2022

(1) Introduction: In response to patient concerns about breast cancer recurrence, increased use of breast magnetic resonance imaging and genetic testing, and advancements in breast reconstruction techniques, mastectomy rates have been observed to ris...

  • Article
  • Open Access
15 Citations
3,200 Views
10 Pages

Assessment of Mastectomy Skin Flaps for Immediate Reconstruction with Implants via Thermal Imaging—A Suitable, Personalized Approach?

  • Hanna Luze,
  • Sebastian Philipp Nischwitz,
  • Paul Wurzer,
  • Raimund Winter,
  • Stephan Spendel,
  • Lars-Peter Kamolz and
  • Vesna Bjelic-Radisic

Background: Impaired perfusion of the remaining skin flap after subcutaneous mastectomy can cause wound-healing disorders and consecutive necrosis. Personalized intraoperative imaging, possibly performed via the FLIR ONE thermal-imaging device, may a...

  • Article
  • Open Access
6 Citations
3,154 Views
17 Pages

23 February 2022

Autologous immediate breast reconstruction in large and ptotic breasts remains challenging. We aimed to identify independent risk factors for impaired wound healing and nipple necrosis after skin reducing wise pattern mastectomy in autologous reconst...

  • Guidelines
  • Open Access
1 Citations
1,775 Views
35 Pages

Postmastectomy Breast Reconstruction in Patients with Non-Metastatic Breast Cancer: An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline

  • Toni Zhong,
  • Glenn G. Fletcher,
  • Muriel Brackstone,
  • Simon G. Frank,
  • Renee Hanrahan,
  • Vivian Miragias,
  • Christiaan Stevens,
  • Danny Vesprini,
  • Alyssa Vito and
  • Frances C. Wright

Several postmastectomy breast reconstruction techniques and procedures have been implemented, although with limited evaluation of benefits and adverse effects. We conducted a systematic review on the plane and timing of reconstruction, and on the use...

  • Article
  • Open Access
7 Citations
3,199 Views
18 Pages

Factors Influencing Residual Glandular Breast Tissue after Risk-Reducing Mastectomy in Genetically Predisposed Individuals Detected by MRI Mammography

  • Frederic Dietzel,
  • Leoni Kolberg,
  • Anne Sophie Vesper,
  • Jürgen Hoffmann,
  • Carolin Nestle-Krämling,
  • Karin Zwiefel,
  • Verena Friebe,
  • Lino M. Sawicki,
  • Nils Martin Bruckmann and
  • Svjetlana Mohrmann
  • + 5 authors

29 January 2023

Purpose: This study seeks to evaluate MR imaging morphological factors and other covariates that influence the presence of residual glandular tissue after risk-reducing mastectomy in patients with a familial predisposition. Methods: We analyzed women...

  • Article
  • Open Access
2 Citations
1,873 Views
21 Pages

Video-Assisted Mastectomy with Immediate Breast Reconstruction: First Clinical Experience and Outcomes in an Eastern European Medical Center

  • Adrian Daniel Tulin,
  • Daniela-Elena Ion,
  • Adelaida Avino,
  • Daniela-Elena Gheoca-Mutu,
  • Abdalah Abu-Baker,
  • Andrada-Elena Țigăran,
  • Teodora Timofan,
  • Ileana Ostafi,
  • Cristian Radu Jecan and
  • Laura Răducu

7 July 2025

Background/Objectives: The aim of this case series is to evaluate the outcomes and safety of video-assisted mastectomy, illustrating the harmonious collaboration of oncologic and plastic surgery. This novel minimally invasive technique allows immedia...

  • Case Report
  • Open Access
1 Citations
2,875 Views
9 Pages

Symptomatic Calcifications after Mastectomy: A Rare Case Report with a Review of the Literature

  • Jan Žatecký,
  • Oldřich Coufal,
  • Dobroslav Sekret and
  • Matúš Peteja

26 February 2024

Introduction: Symptomatic calcifications of the breast or skin after breast cancer surgery and adjuvant radiotherapy are a rare entity, with only a few case reports published worldwide, reducing the patient’s quality of life, whilst asymptomati...

  • Article
  • Open Access
916 Views
12 Pages

Short-Term Outcomes of Post-Mastectomy Immediate Pre-Pectoral Reconstruction with Implant and Acellular Dermal Matrix

  • Beatriz Costeira,
  • Beatriz Gonçalves,
  • António Soares,
  • Rodrigo Oom,
  • Cristina Sousa Costa,
  • João Vargas Moniz,
  • Nuno Abecasis and
  • Catarina Rodrigues dos Santos

11 October 2025

Introduction: Pre-pectoral breast reconstruction using implant and acellular dermal matrix (ADM) has become one of the main techniques for immediate reconstruction after mastectomy, with variable approaches and complication rates reported in literatu...

  • Systematic Review
  • Open Access
1 Citations
1,491 Views
15 Pages

16 April 2025

Background: Breast cancer, irrespective of gender, stands as the most prevalent cancer globally, with an annual estimate of 2.3 million new cases. Surgical intervention, including therapeutic mastectomy (excluding prophylactic procedures), is perform...

  • Article
  • Open Access
8 Citations
3,423 Views
14 Pages

Satisfaction with Long-Term Aesthetic and 10 Years Oncologic Outcome following Risk-Reducing Mastectomy and Implant-Based Breast Reconstruction with or without Nipple Preservation

  • Rachel Louise O’Connell,
  • Marios Konstantinos Tasoulis,
  • Evguenia Hristova,
  • Victoria Teoh,
  • Ana Agusti,
  • Ann Ward,
  • Catherine Montgomery,
  • Kabir Mohammed,
  • Janet Self and
  • Gerald Gui
  • + 1 author

24 July 2022

Incidence of bilateral risk-reducing mastectomies (RRMs) is increasing. The aim of this study was to compare satisfaction, aesthetic and oncological outcomes in women undergoing RRM with implant-based reconstruction comparing nipple-sparing mastectom...

  • Article
  • Open Access
10 Citations
6,407 Views
10 Pages

Comparative Morphological Effects of Cold-Blade, Electrosurgical, and Plasma Scalpels on Dog Skin

  • Luca Lacitignola,
  • Salvatore Desantis,
  • Giovanni Izzo,
  • Francesco Staffieri,
  • Roberta Rossi,
  • Leonardo Resta and
  • Antonio Crovace

12 January 2020

The aim of the present study was to evaluate the histological results of the Onemytis® plasma surgery device with Airplasma® technology. We compared the efficacy and the effect on tissues of the new plasma electrocoagulation system with electrosurger...

  • Article
  • Open Access
1 Citations
1,259 Views
12 Pages

Indocyanine Green Angiography to Predict Complications in Subcutaneous Mastectomy: A Single-Center Experience

  • Letizia Cuniolo,
  • Raquel Diaz,
  • Dafne Anastasia,
  • Federica Murelli,
  • Chiara Cornacchia,
  • Francesca Depaoli,
  • Marco Gipponi,
  • Cecilia Margarino,
  • Chiara Boccardo and
  • Piero Fregatti
  • + 6 authors

10 June 2025

Background/Objectives: In the setting of breast surgery, indocyanine green angiography (ICGA) allows estimating the perfusion of cutaneous tissues during surgical interventions, in order to reduce vascularization-related complications. This study has...

  • Article
  • Open Access
2 Citations
1,640 Views
17 Pages

Size Does Matter: Mastectomy Flap Thickness as an Independent Decisional Factor for the Peri-Prosthetic Device Choice in Prepectoral Breast Reconstruction

  • Juste Kaciulyte,
  • Silvia Sordi,
  • Gianluigi Luridiana,
  • Marco Marcasciano,
  • Federico Lo Torto,
  • Enrico Cavalieri,
  • Luca Codolini,
  • Roberto Cuomo,
  • Warren Matthew Rozen and
  • Donato Casella
  • + 2 authors

7 December 2024

Background. In alloplastic breast reconstruction, the choice of implant positioning and the selection of periprosthetic devices is a critical and challenging decision. Surgeons must navigate between various biologic and synthetic meshes, including ac...

  • Article
  • Open Access
2 Citations
2,050 Views
10 Pages

Impact of the Prepectoral Breast Reconstruction Assessment Score on Expander-Based Reconstruction Success

  • Federico Lo Torto,
  • Gianmarco Turriziani,
  • Sara Carella,
  • Alessia Pagnotta and
  • Diego Ribuffo

28 October 2024

Background/Objectives: The rising incidence of breast cancer has led to more mastectomies and increased demand for reconstruction. While retropectoral reconstruction with expanders is common, it has complications like postoperative pain and animation...

  • Article
  • Open Access
8 Citations
2,564 Views
13 Pages

30 October 2024

Background: Skin- (SSM) and nipple-sparing (NSM) mastectomies are frequently performed surgeries with a considerable risk for post-operative hematoma or seroma. Tranexamic acid (TXA) is a potent antifibrinolytic drug commonly used in many surgical fi...

  • Case Report
  • Open Access
3 Citations
2,905 Views
9 Pages

A Customized 3D-Printed Bolus for High-Risk Breast Cancer with Skin Infiltration: A Pilot Study

  • Silvia Takanen,
  • Anna Ianiro,
  • Paola Pinnarò,
  • Erminia Infusino,
  • Laura Marucci,
  • Antonella Soriani,
  • Giuseppe Sanguineti and
  • Giuseppe Iaccarino

5 September 2024

Background: In high-risk breast cancer patients with skin infiltration, the administration of a uniform dose to superficial tissues is fundamental in order to reduce local skin relapse. A personalized bolus may prevent the potential inadequate dose d...

  • Review
  • Open Access
6 Citations
4,059 Views
14 Pages

Use of Robotic Surgery in Plastic and Reconstructive Surgery: A Narrative Review

  • Jennifer Novo,
  • Ishith Seth,
  • Yi Mon,
  • Akshay Soni,
  • Olivia Elkington,
  • Gianluca Marcaccini and
  • Warren M. Rozen

Background/Objectives: Robotic systems offer enhanced precision, dexterity, and visualization, which are essential in addressing the complex nature of plastic surgery procedures. Despite widespread adoption in other surgical specialties, such as urol...

  • Article
  • Open Access
1 Citations
2,402 Views
11 Pages

24 December 2024

Background: Breast cancer is the most common cancer among women. The number of cases is increasing among young women, and consequently, breast reconstructions are performed more often. Postoperative complications, wound healing, and the quality of sc...

  • Article
  • Open Access
2 Citations
1,733 Views
11 Pages

Fat Grafting and Prepectoral Prosthetic Reconstruction with Polyurethane-Covered Implants: Protective Role against Adjuvant Radiotherapy

  • Liliana Barone Adesi,
  • Federico Taraschi,
  • Giulia Macrì,
  • Lorenzo Scardina,
  • Alba Di Leone,
  • Gianluca Franceschini and
  • Marzia Salgarello

23 August 2024

Background/Objectives: Breast cancer treatment increasingly incorporates immediate prepectoral prosthetic reconstruction after conservative mastectomy, including nipple-sparing (NSMs) and skin-sparing mastectomies (SSMs). Although recent data from th...

  • Article
  • Open Access
117 Views
11 Pages

Symptomatic Outcomes After Autologous Fat Grafting in Irradiated Postmastectomy Chest Wall

  • Razvan George Bogdan,
  • Mara Nicolau,
  • Alina Helgiu and
  • Zorin Petrisor Crainiceanu

22 January 2026

Background/Objectives: Radiotherapy of the chest wall after mastectomy frequently leads to fibrosis, reduced tissue elasticity, erythema, pain and chronic skin-related symptoms that complicate reconstructive strategies. Autologous fat grafting has be...

  • Article
  • Open Access
5 Citations
3,421 Views
22 Pages

Implant-Based Breast Reconstruction after Risk-Reducing Mastectomy in BRCA Mutation Carriers: A Single-Center Retrospective Study

  • Emanuele Cammarata,
  • Francesca Toia,
  • Matteo Rossi,
  • Calogero Cipolla,
  • Salvatore Vieni,
  • Antonino Speciale and
  • Adriana Cordova

Women with BRCA gene mutations have a higher lifetime risk of developing breast cancer. Furthermore, cancer is usually diagnosed at a younger age compared to the wild-type counterpart. Strategies for risk management include intensive surveillance or...

  • Review
  • Open Access
6 Citations
4,542 Views
17 Pages

The Utility of Indocyanine Green Angiography in Breast Reconstruction to Detect Mastectomy Skin Flap Necrosis and Free Flap Perfusion: An Umbrella Review

  • Nicholas Fadell,
  • Flora Laurent,
  • Sai Anusha Sanka,
  • Esther Ochoa,
  • Lauren Yaeger,
  • Xiaowei Li,
  • Matthew D. Wood,
  • Justin M. Sacks and
  • Saif Badran

Two of the greatest challenges in breast reconstruction are mastectomy skin flap necrosis (MSFN) and autologous flap failure. This review summarizes current evidence regarding the usage of indocyanine green angiography (ICGA) in breast reconstruction...

  • Communication
  • Open Access
2 Citations
1,882 Views
8 Pages

Improved Rate of Negative Margins for Inflammatory Breast Cancer Using Intraoperative Frozen Section Analysis

  • Joshua Kong,
  • Sudeshna Bandyopadhyay,
  • Wei Chen,
  • Faisal Al-Mufarrej,
  • Lydia Choi and
  • Mary A. Kosir

16 September 2023

Background: Inflammatory breast cancer (IBC) is a rare and aggressive form of breast cancer with a poor survival rate. Modified radical mastectomy (MRM) with negative pathologic margins is critical for improved survival. We aim to study the potential...

  • Review
  • Open Access
1 Citations
4,478 Views
24 Pages

Recurrent Erysipelas: Clinical Challenges and Strategies for Prevention—A Narrative Literature Review

  • Dominika Maria Jaskóła-Polkowska,
  • Krystian Blok,
  • Anna Skibińska and
  • Andrzej Chciałowski

Recurrent erysipelas is a common and clinically significant condition that poses challenges for both patients and healthcare systems. Each episode may damage lymphatic vessels, leading to chronic lymphedema, which perpetuates the risk of further rela...

  • Article
  • Open Access
3 Citations
2,558 Views
13 Pages

Treatment of Capsular Contracture in Previously Irradiated Breasts Implants and Expanders with the Use of Porcine Acellular Dermal Matrices: Outcomes and Complications

  • Andrea Vittorio Emanuele Lisa,
  • Riccardo Carbonaro,
  • Manuela Bottoni,
  • Giulia Colombo,
  • Marika Gentilucci,
  • Valeriano Vinci,
  • Edvin Ostapenko,
  • Luca Nicosia,
  • Francesca De Lorenzi and
  • Mario Rietjens

23 September 2024

Background: Radiation therapy is a crucial component of breast cancer treatment. However, it is well known to increase the risk of unsatisfactory cosmetic outcomes and higher complication rates. The aim of this study is to provide further insight int...

  • Article
  • Open Access
2,412 Views
16 Pages

A Non-Invasive Deep Photoablation Technique to Inhibit DCIS Progression and Induce Antitumor Immunity

  • Kensuke Kaneko,
  • Hiroshi Nagata,
  • Xiao-Yi Yang,
  • Joshua Ginzel,
  • Zachary Hartman,
  • Jeffrey Everitt,
  • Philip Hughes,
  • Timothy Haystead,
  • Michael Morse and
  • Takuya Osada
  • + 1 author

23 November 2022

Ductal carcinoma in situ (DCIS) of the breast is often managed by lumpectomy and radiation or mastectomy, despite its indolent features. Effective non-invasive treatment strategies could reduce the morbidity of DCIS treatment. We have exploited the h...

  • Article
  • Open Access
1,388 Views
15 Pages

15 October 2025

Objectives: In this study, we aimed to assess the effects of complete decongestive therapy (CDT) on reducing lymphedema and enhancing gross motor strength (GMS), functional ability in the upper arm, quality of life (QoL), and pain relief among women...