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Article

3 Citations

4,025 Views

12 Pages

Impact of Molecular Modifications on the Immunogenicity and Efficacy of Recombinant Raccoon Poxvirus-Vectored Rabies Vaccine Candidates in Mice

Carly M. Malavé,
Jaime Lopera-Madrid,
Lex G. Medina-Magües,
Tonie E. Rocke and
Jorge E. Osorio

Vaccines2021, 9(12), 1436;https://doi.org/10.3390/vaccines9121436

4 December 2021

Rabies is an ancient disease that is responsible for approximately 59,000 human deaths annually. Bats (Order Chiroptera) are thought to be the original hosts of rabies virus (RABV) and currently account for most rabies cases in wildlife in the Americ...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)

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Article

28 Citations

8,076 Views

13 Pages

A Recombinant Raccoon Poxvirus Vaccine Expressing both Yersinia pestis F1 and Truncated V Antigens Protects Animals against Lethal Plague

Tonie E. Rocke,
Brock Kingstad-Bakke,
Willy Berlier and
Jorge E. Osorio

Vaccines2014, 2(4), 772-784;https://doi.org/10.3390/vaccines2040772

27 October 2014

In previous studies, we demonstrated in mice and prairie dogs that simultaneous administration of two recombinant raccoon poxviruses (rRCN) expressing Yersinia pestis antigens (F1 and V307—a truncated version of the V protein) provided superior prote...

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