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  • Article
  • Open Access
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14 Pages

Beyond Addiction: Burden of Polypharmacy and Risk in Frail Patients with Substance Use Disorder

  • L. Goretti Santiago Gutiérrez,
  • Daida Alberto Armas,
  • Verónica Hernández García,
  • Juan Ramón Santana Ayala,
  • Roberto García Sánchez,
  • Soraya Paz Montelongo,
  • Ángel J. Gutiérrez,
  • Arturo Hardisson de la Torre and
  • Carmen Rubio Armendáriz

1 January 2026

Substance use disorder (SUD) is a chronic and clinically complex condition, frequently complicated by significant organic and psychiatric comorbidities. Most patients are polymedicated and require opioid substitution programs (OSPs). This complexity...

(This article belongs to the Section Pharmacy Practice and Practice-Based Research)