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Oxidative Oligomerization of DBL Catechol, a potential Cytotoxic Compound for Melanocytes, Reveals the Occurrence of Novel Ionic Diels-Alder Type Additions

  • Manickam Sugumaran,
  • Kubra Umit,
  • Jason Evans,
  • Rachel Muriph,
  • Shosuke Ito and
  • Kazumasa Wakamatsu
Int. J. Mol. Sci.2020, 21(18), 6774;https://doi.org/10.3390/ijms21186774

15 September 2020

The exposure of human skin to 4-(4-hydroxyphenyl)-2-butanone (raspberry ketone, RK) is known to cause chemical/occupational leukoderma. RK is a carbonyl derivative of 4-(4-hydroxyphenyl)-2-butanol (rhododendrol), a skin whitening agent that was found...

(This article belongs to the Special Issue Melanins and Melanogenesis 2.0: From Nature to Applications)
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