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Article

18 Citations

4,416 Views

9 Pages

Atypical Lindenane-Type Sesquiterpenes from Lindera myrrha

Thuc-Huy Duong,
Mehdi A. Beniddir,
Nguyen T. Trung,
Cam-Tu D. Phan,
Van Giau Vo,
Van-Kieu Nguyen,
Quynh-Loan Le,
Hoang-Dung Nguyen and
Pierre Le Pogam

Molecules2020, 25(8), 1830;https://doi.org/10.3390/molecules25081830

16 April 2020

Two new lindenane sesquiterpenes were obtained from the roots of Lindera myrrha. These compounds were structurally elucidated by HRMS data, extensive NMR analyses, and comparison between experimental and theoretical ¹³C-NMR data. Myrrhalindenane A is...

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Article

8 Citations

2,247 Views

12 Pages

Chlorahololide D, a Lindenane-Type Sesquiterpenoid Dimer from Chloranthus holostegius Suppressing Breast Cancer Progression

Ying Li,
Wenhui Liu,
Jing Xu and
Yuanqiang Guo

Molecules2023, 28(20), 7070;https://doi.org/10.3390/molecules28207070

13 October 2023

Aimed at discovering small molecules as anticancer drugs or lead compounds from plants, a lindenane-type sesquiterpene dimer, chlorahololide D, was isolated from Chloranthus holostegius. The literature review showed that there were few reports on the...

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Short Note

24 Citations

7,743 Views

9 Pages

Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp.

Shih-Yao Kao,
Jui-Hsin Su,
Tsong-Long Hwang,
Jyh-Horng Sheu,
Zhi-Hong Wen,
Yang-Chang Wu and
Ping-Jyun Sung

Mar. Drugs2011, 9(9), 1534-1542;https://doi.org/10.3390/md9091534

14 September 2011

Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were establi...

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Article

7 Citations

3,960 Views

19 Pages

Chlojaponilactone B Attenuates THP-1 Macrophage Pyroptosis by Inhibiting the TLR/MyD88/NF-κB Pathway

Qiyin Wen,
Bingjinfeng Zhan,
Lu Jin,
Zijing Peng,
Ju Liu,
Longping Zhu,
Depo Yang,
Xinjun Xu,
Lixia Zhang and
Zhimin Zhao
+ 1 author

Pharmaceuticals2024, 17(3), 402;https://doi.org/10.3390/ph17030402

21 March 2024

Pyroptosis, an innate immune response, plays a crucial role in the pathological process of inflammatory diseases. Although pyroptosis blockade is considered a potential therapeutic strategy, no ideal candidate drug has been identified. The natural pr...

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Article

24 Citations

10,242 Views

14 Pages

Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway

Shaoxia Ye,
Qiyao Zheng,
Yang Zhou,
Bai Bai,
Depo Yang and
Zhimin Zhao

Molecules2019, 24(20), 3731;https://doi.org/10.3390/molecules24203731

16 October 2019

The lindenane-type sesquiterpenoid chlojaponilactone B (1), isolated from Chloranthus japonicus, has been reported to possess anti-inflammatory properties. The present study aimed to further explore the molecular mechanisms underlying the anti-inflam...

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Article

35 Citations

8,282 Views

14 Pages

Anti-Inflammatory Effects of Chloranthalactone B in LPS-Stimulated RAW264.7 Cells

Xueqin Li,
Jun Shen,
Yunyao Jiang,
Ting Shen,
Long You,
Xiaobo Sun,
Xudong Xu,
Weicheng Hu,
Haifeng Wu and
Gongcheng Wang

Int. J. Mol. Sci.2016, 17(11), 1938;https://doi.org/10.3390/ijms17111938

22 November 2016

Chloranthalactone B (CTB), a lindenane-type sesquiterpenoid, was obtained from the Chinese medicinal herb Sarcandra glabra, which is frequently used as a remedy for inflammatory diseases. However, the anti-inflammatory mechanisms of CTB have not been...

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