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8 Results Found

  • Article
  • Open Access
7 Citations
5,524 Views
25 Pages
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Mapping-by-Sequencing Reveals Genomic Regions Associated with Seed Quality Parameters in Brassica napus

  • Hanna Marie Schilbert,
  • Boas Pucker,
  • David Ries,
  • Prisca Viehöver,
  • Zeljko Micic,
  • Felix Dreyer,
  • Katrin Beckmann,
  • Benjamin Wittkop,
  • Bernd Weisshaar and
  • Daniela Holtgräwe
Genes2022, 13(7), 1131;https://doi.org/10.3390/genes13071131

23 June 2022

Rapeseed (Brassica napus L.) is an important oil crop and has the potential to serve as a highly productive source of protein. This protein exhibits an excellent amino acid composition and has high nutritional value for humans. Seed protein content (...

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  • Article
  • Open Access
2 Citations
2,876 Views
10 Pages
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The Polymorphism rs17300539 in the Adiponectin Promoter Gene Is Related to Metabolic Syndrome, Insulin Resistance, and Adiponectin Levels in Caucasian Patients with Obesity

  • Daniel de Luis Roman,
  • Olatz Izaola Jauregui and
  • David Primo Martin
Nutrients2023, 15(24), 5028;https://doi.org/10.3390/nu15245028

7 December 2023

Background and Aims: The present study was designed to investigate SNP rs17300539 in the ADIPOQ gene and its relationships with obesity, metabolic syndrome (MS), and serum circulating adiponectin. Methods: The present design involved a Caucasian popu...

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  • Article
  • Open Access
5 Citations
3,054 Views
11 Pages
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Association between ABCB1 rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults

  • Justin Matheson,
  • Yollanda J. Zhang,
  • Bruna Brands,
  • Christine M. Wickens,
  • Arun K. Tiwari,
  • Clement C. Zai,
  • James L. Kennedy and
  • Bernard Le Foll
Brain Sci.2022, 12(9), 1189;https://doi.org/10.3390/brainsci12091189

3 September 2022

Genetic influences on acute responses to psychoactive drugs may contribute to individual variability in addiction risk. ABCB1 is a human gene that encodes P-glycoprotein, an ATP-dependent efflux pump that may influence the pharmacokinetics of delta-9...

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  • Article
  • Open Access
103 Citations
7,555 Views
15 Pages
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A Polymorphism at the Translation Start Site of the Vitamin D Receptor Gene Is Associated with the Response to Anti-Osteoporotic Therapy in Postmenopausal Women from Southern Italy

  • Valeria Conti,
  • Giusy Russomanno,
  • Graziamaria Corbi,
  • Giuseppe Toro,
  • Vittorio Simeon,
  • Walter Filippelli,
  • Nicola Ferrara,
  • Michela Grimaldi,
  • Valeria D'Argenio and
  • Amelia Filippelli
Int. J. Mol. Sci.2015, 16(3), 5452-5466;https://doi.org/10.3390/ijms16035452

10 March 2015

The present study investigated the effect of two single nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, rs1544410 A/G and rs2228570 C/T, in modulating bone mineral density (BMD) and the response to treatment with bisphosphonates...

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  • Article
  • Open Access
27 Citations
8,131 Views
13 Pages
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Effects of Delta-Aminolevulinic Acid Dehydratase Polymorphisms on Susceptibility to Lead in Han Subjects from Southwestern China

  • Yuelin Yang,
  • Jin Wu and
  • Pin Sun
Int. J. Environ. Res. Public Health2012, 9(7), 2326-2338;https://doi.org/10.3390/ijerph9072326

2 July 2012

This study is to determine the distribution of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism among Han subjects of the Chinese population and to study whether the polymorphism in the ALAD gene modifies the toxicity of lead in lead-exp...

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  • Open Access
1,257 Views
17 Pages
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Genomic Evolution of SARS-CoV-2 Variants of Concern Under In Vitro Neutralising Selection Pressure Following Two Doses of the Pfizer-BioNTech BNT162b2 COVID-19 Vaccine

  • Kerri Basile,
  • Jessica E. Agius,
  • Winkie Fong,
  • Kenneth McPhie,
  • Danny Ko,
  • Linda Hueston,
  • Connie Lam,
  • David Pham,
  • Sharon C.-A. Chen and
  • Rebecca J. Rockett
  • + 4 authors
Viruses2025, 17(9), 1161;https://doi.org/10.3390/v17091161

25 August 2025

We aimed to explore SARS-CoV-2 evolution during in vitro neutralisation using next generation sequencing, and to determine whether sera from individuals immunised with two doses of the Pfizer-BioNTech vaccine (BNT162b2) were as effective at neutralis...

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  • Open Access
9 Citations
3,216 Views
17 Pages
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Contrasting Epidemiology and Population Genetics of COVID-19 Infections Defined by Multilocus Genotypes in SARS-CoV-2 Genomes Sampled Globally

  • Felicia Hui Min Chan,
  • Ricardo Ataide,
  • Jack S. Richards and
  • Charles A. Narh
Viruses2022, 14(7), 1434;https://doi.org/10.3390/v14071434

29 June 2022

Since its emergence in 2019, SARS-CoV-2 has spread and evolved globally, with newly emerged variants of concern (VOCs) accounting for more than 500 million COVID-19 cases and 6 million deaths. Continuous surveillance utilizing simple genetic tools is...

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  • Open Access
3 Citations
1,891 Views
28 Pages
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Impact of African-Specific ACE2 Polymorphisms on Omicron BA.4/5 RBD Binding and Allosteric Communication Within the ACE2–RBD Protein Complex

  • Victor Barozi and
  • Özlem Tastan Bishop
Int. J. Mol. Sci.2025, 26(3), 1367;https://doi.org/10.3390/ijms26031367

6 February 2025

Severe acute respiratory symptom coronavirus 2 (SARS-CoV-2) infection occurs via the attachment of the spike (S) protein’s receptor binding domain (RBD) to human ACE2 (hACE2). Natural polymorphisms in hACE2, particularly at the interface, may a...

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