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Keywords = continuous flow separation

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23 pages, 2936 KB  
Article
Performance of a High-Molecular-Weight AM/AA Copolymer in a CO2–Water Polymer Hybrid Fracturing Fluid Under High-Temperature and High-Pressure Conditions
by Tengfei Chen, Shutao Zhou, Tingwei Yao, Meilong Fu, Zhigang Wen and Quanhuai Shen
Polymers 2026, 18(3), 418; https://doi.org/10.3390/polym18030418 - 5 Feb 2026
Abstract
To reduce water consumption and potential formation damage associated with conventional water-based fracturing fluids while improving the proppant-carrying and flow adaptability of CO2-based systems without relying on specialized CO2 thickeners, a CO2–water polymer hybrid fracturing fluid was developed [...] Read more.
To reduce water consumption and potential formation damage associated with conventional water-based fracturing fluids while improving the proppant-carrying and flow adaptability of CO2-based systems without relying on specialized CO2 thickeners, a CO2–water polymer hybrid fracturing fluid was developed using an AM/AA copolymer (poly(acrylamide-co-acrylic acid), P(AM-co-AA)) as the thickening agent for the aqueous phase. Systematic experimental investigations were conducted under high-temperature and high-pressure conditions. Fluid-loss tests at different CO2 volume fractions show that the CO2–water polymer hybrid fracturing fluid system achieves a favorable balance between low fluid loss and structural continuity within the range of 30–50% CO2, with the most stable fluid-loss behavior observed at 40% CO2. Based on this ratio window, static proppant-carrying experiments indicate controllable settling behavior over a temperature range of 20–80 °C, leading to the selection of 60% polymer-based aqueous phase + 40% CO2 as the optimal mixing ratio. Rheological results demonstrate pronounced shear-thinning behavior across a wide thermo-pressure range, with viscosity decreasing systematically with increasing shear rate and temperature while maintaining continuous and reproducible flow responses. Pipe-flow tests further reveal that flow resistance decreases monotonically with increasing flow velocity and temperature, indicating stable transport characteristics. Phase visualization observations show that the CO2–water polymer hybrid fracturing fluid system exhibits a uniform milky dispersed appearance under moderate temperature or elevated pressure, whereas bubble-dominated structures and spatial phase separation gradually emerge under high-temperature and relatively low-pressure static conditions, highlighting the sensitivity of phase stability to thermo-pressure conditions. True triaxial hydraulic fracturing experiments confirm that the CO2–water polymer hybrid fracturing fluid enables stable fracture initiation and sustained propagation under complex stress conditions. Overall, the results demonstrate that the AM/AA copolymer-based aqueous phase can provide effective viscosity support, proppant-carrying capacity, and flow adaptability for CO2–water polymer hybrid fracturing fluid over a wide thermo-pressure range, confirming the feasibility of this approach without the use of specialized CO2 thickeners. Full article
(This article belongs to the Section Polymer Analysis and Characterization)
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11 pages, 1467 KB  
Article
Continuous Size-Based Particle Separation Using Inertial Force and Deterministic Lateral Displacement
by Yile Xie, Zichen Wang, Wenjia Xie, Jeong Min Oh, Chun Lai, Jingqian Zhang and Raymond H. W. Lam
Micromachines 2026, 17(2), 194; https://doi.org/10.3390/mi17020194 - 31 Jan 2026
Viewed by 170
Abstract
Continuous, label-free particle separation is essential for a broad range of biochemical and biomedical applications. Here, we present a microfluidic device that integrates inertial focusing and deterministic lateral displacement (DLD) within a compact channel architecture to achieve size-based particle sorting under laminar flow [...] Read more.
Continuous, label-free particle separation is essential for a broad range of biochemical and biomedical applications. Here, we present a microfluidic device that integrates inertial focusing and deterministic lateral displacement (DLD) within a compact channel architecture to achieve size-based particle sorting under laminar flow conditions. The design combines upstream curved channels for initial lateral positioning with downstream micropillar-embedded curved channels to enhance separation resolution. Theoretical analysis and numerical simulations were performed to optimize channel geometry and micropillar arrangement, predicting size-dependent lateral displacement driven by centrifugal forces and pillar-induced constraints. Experimental validation using glass beads of two distinct sizes (8 μm and 15 μm) demonstrated a separation efficiency exceeding 93% across a range of flow rates and particle concentrations. The device offers a simple, cost-effective, and scalable solution for passive particle sorting without external fields or labeling. The flexibility of the design configuration can be adapted for diverse applications, including extracellular vesicles, barcoded hydrogel particles, and engineered drug-delivery carriers. Full article
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23 pages, 4904 KB  
Article
Integrated Furnace-to-SCR CFD Modeling of a Large Coal-Fired Boiler: Combustion Characteristics and Flow Optimization over a Wide Load Range
by Xiangdong Feng, Jin Xiang, Zhen Chen and Guangxue Zhang
Processes 2026, 14(3), 485; https://doi.org/10.3390/pr14030485 - 30 Jan 2026
Viewed by 217
Abstract
Growing renewable penetration increases deep peak-shaving demands, making stable wide-load operation of coal-fired boilers essential. A full-process CFD model of a 660 MW ultra-supercritical boiler was established, covering the furnace, heat-transfer surfaces, rear-pass duct, and selective catalytic reduction (SCR) system. Simulations at 25–100% [...] Read more.
Growing renewable penetration increases deep peak-shaving demands, making stable wide-load operation of coal-fired boilers essential. A full-process CFD model of a 660 MW ultra-supercritical boiler was established, covering the furnace, heat-transfer surfaces, rear-pass duct, and selective catalytic reduction (SCR) system. Simulations at 25–100% boiler maximum continuous rating (BMCR) quantified load effects on combustion and emissions. Predicted furnace outlet temperature and major flue-gas species matched field data with deviations within ±6%. Lowering the load from 100% to 25% BMCR contracted the high-temperature core in the furnace and reduced mean temperature and mixing. Furnace nitrogen oxides (NOx) formation decreased as the load decreased. However, NOx at 25% BMCR increased because separated over-fire air (SOFA) was not applied. Reduced combustion intensity increased the level of unburned carbon in fly ash, which rose by approximately 3.5% at 25% BMCR, relative to the rated condition. Pronounced flow maldistribution also appeared at 25% BMCR. The SCR-inlet flow analysis indicated that the original guide vane design was not suitable for wide-load operation and that inlet-velocity uniformity deteriorated, especially at low loads. An optimized guide vane scheme is proposed, improving SCR-inlet uniformity over the full load range while mitigating ash deposition and erosion risks. Full article
(This article belongs to the Special Issue Advances in Combustion Processes: Fundamentals and Applications)
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8 pages, 1453 KB  
Communication
Double-Sided Illuminated Electrospun PAN TiO2-Cu2O Membranes for Enhanced CO2 Photoreduction to Methanol
by Mathieu Grandcolas
Catalysts 2026, 16(1), 107; https://doi.org/10.3390/catal16010107 - 22 Jan 2026
Viewed by 200
Abstract
Photocatalytic reduction of CO2 into value-added chemicals offers a sustainable route to mitigate greenhouse gas emissions while producing renewable fuels. However, conventional TiO2-based systems suffer from limited visible-light activity and inefficient reactor configurations. Here, we developed electrospun polyacrylonitrile (PAN) membranes [...] Read more.
Photocatalytic reduction of CO2 into value-added chemicals offers a sustainable route to mitigate greenhouse gas emissions while producing renewable fuels. However, conventional TiO2-based systems suffer from limited visible-light activity and inefficient reactor configurations. Here, we developed electrospun polyacrylonitrile (PAN) membranes embedded with TiO2-Cu2O heterojunction nanoparticles and integrated them into a custom crossflow photocatalytic membrane reactor. The reactor employed bifacial illumination using a solar simulator (front) and a xenon/mercury lamp (back), each calibrated to 1 Sun (100 mW·cm−2). Membrane morphology was characterized by SEM, and chemical composition was confirmed by XPS. Photocatalytic performance was evaluated in CO2-saturated 0.5 M potassium bicarbonate solution under continuous flow. The PAN/ TiO2-Cu2O membrane exhibited a methanol production rate of approximately 300 μmol·g−1·h−1 under dual-light illumination, outperforming single illumination, PAN-TiO2, and PAN controls. Enhanced activity is attributed to extended visible-light absorption, improved charge separation at the TiO2-Cu2O heterojunction, and optimized photon flux through bifacial illumination. The electrospun architecture provided high surface area and porosity, facilitating CO2 adsorption and catalyst dispersion. Combining heterojunction engineering with bifacial reactor design significantly improves solar-driven CO2 conversion. This approach offers a scalable pathway for integrating photocatalysis and membrane technology into sustainable fuel synthesis. Full article
(This article belongs to the Special Issue Advanced Semiconductor Photocatalysts)
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23 pages, 7133 KB  
Article
Energy Transfer Characteristics of Surface Vortex Heat Flow Under Non-Isothermal Conditions Based on the Lattice Boltzmann Method
by Qing Yan, Lin Li and Yunfeng Tan
Processes 2026, 14(2), 378; https://doi.org/10.3390/pr14020378 - 21 Jan 2026
Cited by 1 | Viewed by 164
Abstract
During liquid drainage from intermediate vessels in various industrial processes such as continuous steel casting, aircraft fuel supply, and chemical separation, free-surface vortices commonly occur. The formation and evolution of these vortices not only entrain surface slag and gas, but also lead to [...] Read more.
During liquid drainage from intermediate vessels in various industrial processes such as continuous steel casting, aircraft fuel supply, and chemical separation, free-surface vortices commonly occur. The formation and evolution of these vortices not only entrain surface slag and gas, but also lead to deterioration of downstream product quality and abnormal equipment operation. The vortex evolution process exhibits notable three-dimensional unsteadiness, multi-scale turbulence, and dynamic gas–liquid interfacial changes, accompanied by strong coupling effects between temperature gradients and flow field structures. Traditional macroscopic numerical models show clear limitations in accurately capturing these complex physical mechanisms. To address these challenges, this study developed a mesoscopic numerical model for gas-liquid two-phase vortex flow based on the lattice Boltzmann method. The model systematically reveals the dynamic behavior during vortex evolution and the multi-field coupling mechanism with the temperature field while providing an in-depth analysis of how initial perturbation velocity regulates vortex intensity and stability. The results indicate that vortex evolution begins near the bottom drain outlet, with the tangential velocity distribution conforming to the theoretical Rankine vortex model. The vortex core velocity during the critical penetration stage is significantly higher than that during the initial depression stage. An increase in the initial perturbation velocity not only enhances vortex intensity and induces low-frequency oscillations of the vortex core but also markedly promotes the global convective heat transfer process. With regard to the temperature field, an increase in fluid temperature reduces the viscosity coefficient, thereby weakening viscous dissipation effects, which accelerates vortex development and prolongs drainage time. Meanwhile, the vortex structure—through the induction of Taylor vortices and a spiral pumping effect—drives shear mixing and radial thermal diffusion between fluid regions at different temperatures, leading to dynamic reconstruction and homogenization of the temperature field. The outcomes of this study not only provide a solid theoretical foundation for understanding the generation, evolution, and heat transfer mechanisms of vortices under industrial thermal conditions, but also offer clear engineering guidance for practical production-enabling optimized operational parameters to suppress vortices and enhance drainage efficiency. Full article
(This article belongs to the Section Energy Systems)
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8 pages, 441 KB  
Article
Enabling Circular Copper Flows in Electric Motor Lifecycle
by Linda Sandgren, Sri Ram Gnanesh, Erik Johansson, Victoria Van Camp, Magnus Karlberg, Mats Näsström and Roland Larsson
Clean Technol. 2026, 8(1), 16; https://doi.org/10.3390/cleantechnol8010016 - 21 Jan 2026
Viewed by 163
Abstract
Copper is a strategic raw material and an important component in electric motors, widely used across industries because of its excellent conductivity and recyclability. It plays an important role in the transformation from fossil fuel-based systems to green, electrified systems. However, substantial material [...] Read more.
Copper is a strategic raw material and an important component in electric motors, widely used across industries because of its excellent conductivity and recyclability. It plays an important role in the transformation from fossil fuel-based systems to green, electrified systems. However, substantial material losses continue throughout the lifecycle of electric motors, even with copper’s intrinsic capacity for circularity. Also, copper’s increasing demand, which is driven by the emergence of electric vehicles, industrial electrification, and renewable energy infrastructure, poses questions regarding its sustainable supply. The recovery of secondary copper sources from end-of-life (EoL) products is becoming more and more important in this context. However, it is still difficult to achieve circularity of copper, especially from industrial electric motors. This study investigates the challenges of closing the loop for copper during the lifecycle of motors in industrial applications. Based on an examination of EoL strategies, material flow insights, and practical investigation, the research pinpoints significant inefficiencies in the current processes. The widespread use of scraping as an approach of end-of-life management is one significant issue. Most of the electric motors are not built to separate their components, which makes both mechanical and manual disassembly difficult. The quality of recovered copper is thus compromised by the dominance of mixed metal shredding methods in the recycling step. This study highlights the need for systemic changes in addition to technical solutions to address copper circularity issues. It requires a focus on circularity in designing, giving disassembly and metal recovery a priority. This study focuses on circularity and its technological challenges in a value chain of copper. It not only identifies different processes such as supply chain disconnections and design constraints, but it also suggests workable solutions to close the copper flow loop in the electric motor sector. Copper quality and recovery is ultimately a problem involving design, technology, and cooperation, in addition to resources. This study supports the transition to a more sustainable and circular electric motor industry by offering a basis for directing such changes in industry practices and prospective EU regulations. Full article
(This article belongs to the Special Issue Selected Papers from Circular Materials Conference 2025)
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25 pages, 2523 KB  
Article
A Comparative Study of Liquid Film Cooling on a Flat Plate Using SPH and VOF Methods
by Edidiong Michael Umana, Huan Li, Xiufeng Yang, Dmitry Alexandrovich Uglanov and Naresh Kedam
Aerospace 2026, 13(1), 70; https://doi.org/10.3390/aerospace13010070 - 9 Jan 2026
Viewed by 385
Abstract
This numerical study demonstrates the existence of a critical injection momentum threshold necessary for stable liquid film formation, highlighting that either excessive or insufficient momentum degrades cooling performance. This optimization is critical for maximizing cooling effectiveness from short injection holes in high-performance propulsion [...] Read more.
This numerical study demonstrates the existence of a critical injection momentum threshold necessary for stable liquid film formation, highlighting that either excessive or insufficient momentum degrades cooling performance. This optimization is critical for maximizing cooling effectiveness from short injection holes in high-performance propulsion systems. By comparing Smoothed Particle Hydrodynamics (SPH) and Volume of Fluid (VOF) methods, we find that the SPH method predicts a thicker, more continuous coolant film due to its superior mass conservation during interface breakup. A key design insight emerges: cooling performance peaks at a distinct, critical coolant momentum. Insufficient momentum leads to poor coverage, while excess momentum causes film separation and is counter-productive. The identified configuration—defined by a precise combination of flow rate, pressure, and geometry—promotes immediate and stable film formation. The robustness of this finding is confirmed by the agreement between the two numerical methods on film thickness and the captured physical evolution of the film from a pronounced wave to a damped state. Full article
(This article belongs to the Section Aeronautics)
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20 pages, 3725 KB  
Article
Evolution Pattern of Hydraulic Characteristics at a Bridge Site: The Influence of Key Flood Factors
by Zhenchuan Li, Wanheng Li, Pengfei Li, Xuanji Jin and Yao Liu
Water 2026, 18(2), 155; https://doi.org/10.3390/w18020155 - 7 Jan 2026
Viewed by 302
Abstract
Flood factors are key parameters affecting the hydraulic characteristics at a bridge site. Clarifying the development patterns and impacts of flood factors at a bridge site is of great significance for the stability assessment and service safety of bridges. Therefore, the impact analysis [...] Read more.
Flood factors are key parameters affecting the hydraulic characteristics at a bridge site. Clarifying the development patterns and impacts of flood factors at a bridge site is of great significance for the stability assessment and service safety of bridges. Therefore, the impact analysis of flood factors, i.e., the initial flow velocity, scour angle, scour depth, on the evolution pattern of hydraulic characteristics at a bridge site is numerically conducted in this research. The structural model and hydraulic model are first established for numerical analysis. The correctness of models is verified through the existing analytical formula and experimental result. The evolution patterns of hydraulic characteristics at a bridge site are systematically evaluated. The results show that the flow velocity at the upstream side of the bridge exhibits relatively uniform and continuous distribution in both transverse and vertical directions, primarily caused by the obstruction of bridge piers. At the downstream side of the bridge, the flow velocity presents non-uniform development, induced by the horseshoe vortex and flow disturbance near the upstream pier. The coupling effect of the lateral flow velocity component suppressing vertical vortices and complex flow separation induces the distinct flow velocity distributions. Scour depth alters the flow field patterns, thereby influencing the flow’s resistance and acceleration properties. The above development pattern of hydraulic characteristics at the bridge site holds practical significance for conducting detailed analyses of flood impacts on bridges. Full article
(This article belongs to the Section Hydraulics and Hydrodynamics)
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17 pages, 3747 KB  
Article
Design and Testing of the Residual Film Impurity Separation Device for the Recovery Machine of Plastic Film in the Tillage Layer
by Zechen Xu, Yihao Yin, Aiping Shi and Zhi Zhou
Coatings 2026, 16(1), 70; https://doi.org/10.3390/coatings16010070 - 7 Jan 2026
Viewed by 242
Abstract
Due to the continuous improvement in the usage area and retention quality of plastic films in China, the serious residue film pollution faced by China has become a major threat to crop production. To address the aforementioned issues and in accordance with the [...] Read more.
Due to the continuous improvement in the usage area and retention quality of plastic films in China, the serious residue film pollution faced by China has become a major threat to crop production. To address the aforementioned issues and in accordance with the actual demand for residue film recovery machines in the Xinjiang region of China, a residual film impurity separation device suitable for the recovery machine of crop residue films has been designed. The overall structure and working principle of the machine were elaborated. Numerical simulations of the through-flow fan device of the residual film recovery machine were carried out using the ANSYS 2022 (CFX) finite element analysis platform, and the corresponding wind speed range of the fan at rotational speeds of 1000–1400 r/min was obtained. Based on the simulation results, the Depth of Machine Insertion into the Ground, Fan Wind Speed, and Forward Speed of the Machinery were selected as experimental factors, while the residual film recovery rate was taken as the evaluation index. A response surface experiment was conducted, and the optimization analysis was performed using Design-Expert software. The final experimental validation results indicated that when the Depth of Machine Insertion into the Ground was 32 mm, the Forward Speed of the Machinery was 5.29 km/h, and the Fan Wind Speed was 13.67 m/s, the machine could effectively overcome the influence of complex field operating conditions. This parameter combination was identified as the optimal operating condition of the machine, providing a valuable reference for the design and optimization of related agricultural machinery. Full article
(This article belongs to the Section Thin Films)
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14 pages, 4381 KB  
Article
Research on Shockwave/Boundary Layer Interactions Induced by Double Compression Corners Under Hypersonic Quiet and Noise Inflow Conditions
by Dongsheng Zhang, Jinping Li, Hesen Yang and Hua Liang
Aerospace 2026, 13(1), 22; https://doi.org/10.3390/aerospace13010022 - 26 Dec 2025
Viewed by 321
Abstract
The problem of shock wave/boundary layer interaction induced by compression corners widely exists in the external and internal flows of various supersonic/hypersonic aircraft. In practical engineering applications, multistage continuous compression is often used in the fin/rudder structure, while in internal flow, multistage compression [...] Read more.
The problem of shock wave/boundary layer interaction induced by compression corners widely exists in the external and internal flows of various supersonic/hypersonic aircraft. In practical engineering applications, multistage continuous compression is often used in the fin/rudder structure, while in internal flow, multistage compression schemes are usually employed at the inlet to enhance total pressure recovery; therefore, it is necessary to investigate the characteristics of multistage compression corner shockwave/boundary layer interactions. In basic research, it is usually simplified as the double compression corner shockwave/boundary layer interaction issue. In this paper, an experimental study of hypersonic shock/boundary layer interaction characteristics is conducted under quiet and noise inflow conditions, respectively, for the double compression corner model. Using high-speed Schlieren, the typical structure of shockwave/shockwave interaction and shockwave/boundary layer interaction above the corner is explored under both quiet and noisy incoming flow conditions. Then, based on gray average, root-mean-square analysis, Fast Fourier transform, proper orthogonal decomposition, and dynamic mode decomposition methods, the time-average and unsteady characteristics of the double compression corner configuration-induced separation were studied, and a comparative analysis was conducted. The difference law between wind tunnel noise level and interaction characteristics was summarized. Finally, the characteristic length and spectral characteristics of unstable waves that dominated the stability of the plate boundary layer were studied. The formation mechanism of separation is discussed, which provides technical support for the internal and external aerodynamic design and targeted optimization of hypersonic vehicles. Full article
(This article belongs to the Special Issue Fluid Flow Mechanics (4th Edition))
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21 pages, 5360 KB  
Article
Hydraulic Instability Characteristics of Pumped-Storage Units During the Transition from Hot Standby to Power Generation
by Longxiang Chen, Jianguang Li, Lei Deng, Enguo Xie, Xiaotong Yan, Guowen Hao, Huixiang Chen, Hengyu Xue, Ziwei Zhong and Kan Kan
Water 2026, 18(1), 61; https://doi.org/10.3390/w18010061 - 24 Dec 2025
Viewed by 427
Abstract
Against the backdrop of the carbon peaking and neutrality (“dual-carbon”) goals and evolving new-type power system dispatch, the share of pumped-storage hydropower (PSH) in power systems continues to increase, imposing stricter requirements on units for higher cycling frequency, greater operational flexibility, and rapid, [...] Read more.
Against the backdrop of the carbon peaking and neutrality (“dual-carbon”) goals and evolving new-type power system dispatch, the share of pumped-storage hydropower (PSH) in power systems continues to increase, imposing stricter requirements on units for higher cycling frequency, greater operational flexibility, and rapid, stable startup and shutdown. Focusing on the entire hot-standby-to-generation transition of a PSH plant, a full-flow-path three-dimensional transient numerical model encompassing kilometer-scale headrace/tailrace systems, meter-scale runner and casing passages, and millimeter-scale inter-component clearances is developed. Three-dimensional unsteady computational fluid dynamics are determined, while the surge tank free surface and gaseous phase are captured using a volume-of-fluid (VOF) two-phase formula. Grid independence is demonstrated, and time-resolved validation is performed against the experimental model–test operating data. Internal instability structures are diagnosed via pressure fluctuation spectral analysis and characteristic mode identification, complemented by entropy production analysis to quantify dissipative losses. The results indicate that hydraulic instabilities concentrate in the acceleration phase at small guide vane openings, where misalignment between inflow incidence and blade setting induces separation and vortical structures. Concurrently, an intensified adverse pressure gradient in the draft tube generates an axial recirculation core and a vortex rope, driving upstream propagation of low-frequency pressure pulsations. These findings deepen our mechanistic understanding of hydraulic transients during the hot-standby-to-generation transition of PSH units and provide a theoretical basis for improving transitional stability and optimizing control strategies. Full article
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19 pages, 3290 KB  
Article
Magnetically Sculpted Microfluidics for Continuous-Flow Fractionation of Cell Populations by EpCAM Expression Level
by Zhenwei Liang, Xiaolei Guo, Xuanhe Zhang, Yiqing Chen, Chuan Du, Yuan Ma and Jiadao Wang
Micromachines 2026, 17(1), 9; https://doi.org/10.3390/mi17010009 - 22 Dec 2025
Viewed by 367
Abstract
Continuous-flow separation of magnetically labeled cells according to surface-marker expression levels is increasingly needed to study phenotypic heterogeneity and support downstream assays. Here, we present a microfluidic platform that uses spatially engineered soft magnetic strips (SMS) to sculpt lateral magnetic deflection fields for [...] Read more.
Continuous-flow separation of magnetically labeled cells according to surface-marker expression levels is increasingly needed to study phenotypic heterogeneity and support downstream assays. Here, we present a microfluidic platform that uses spatially engineered soft magnetic strips (SMS) to sculpt lateral magnetic deflection fields for quantitative, label-guided cell fractionation. Under a uniform bias field, the SMS generates controllable magnetic gradients within the microchannel, producing distinct lateral velocities among EpCAM-labeled tumor cells that carry different Dynabead loads, which indirectly report membrane protein expression. Multi-outlet collection converts these “race-based” trajectory differences into discrete expression-level-resolved fractions. A COMSOL–MATLAB framework and a force-equivalent metric |(H·∇)H| are used to optimize key structural parameters of the magnetic interface, including strip thickness, width, and vertical spacing from the flow channel. Three journey nodes at 1.5, 3, and 9 mm along the flow path define a three-stage cascade that partitions MDA-MB-231, Caco-2, and A549 cells into four EpCAM-related magnetic subgroups: high (H), medium (M), low (L), and near-negative (N). Experiments show that the sorted fractions follow the expected expression trends reported in the literature, while maintaining high cell recovery (>90%) and viability retention of 98.2 ± 1.3%, indicating compatibility with downstream whole-blood assays and culture. Rather than introducing a new biomarker, this work establishes a quantitative magnetic-field design strategy for continuous microfluidic sorting, in which the spatial configuration of soft magnetic elements is exploited to implement expression-level-dependent fractionation in next-generation magneto-fluidic separation systems. Full article
(This article belongs to the Special Issue Microfluidic Chips for Biomedical Applications)
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26 pages, 6020 KB  
Article
Numerical Investigation of Maneuvering Characteristics for a Submarine Under Horizontal Stern Plane Deflection in Vertical Plane Straight-Line Motion
by Binbin Zou, Yingfei Zan, Ruinan Guo, Shuaihang Wang, Zhenzhong Jin and Qiang Xu
J. Mar. Sci. Eng. 2025, 13(12), 2371; https://doi.org/10.3390/jmse13122371 - 14 Dec 2025
Viewed by 407
Abstract
The maneuverability of a submarine in the vertical plane is a key indicator of navigation safety. However, existing studies typically evaluate maneuvering performance based on hydrodynamic coefficients, often neglecting the flow-field evolution induced by different steering strategies. In this study, a high-fidelity numerical [...] Read more.
The maneuverability of a submarine in the vertical plane is a key indicator of navigation safety. However, existing studies typically evaluate maneuvering performance based on hydrodynamic coefficients, often neglecting the flow-field evolution induced by different steering strategies. In this study, a high-fidelity numerical model for the vertical-plane motion of the DARPA SUBOFF submarine is established using the Reynolds-Averaged Navier–Stokes (RANS) method and validated against benchmark data. Unlike traditional analyses that employ a fixed rudder angle, this work systematically compares three steering strategies with continuously varying rudder angles—trapezoidal, step, and linear steering—examining their motion responses, hydrodynamic performance, and unsteady flow-field evolution. The results show that, although step steering produces the fastest response with the strongest transient characteristics, it also triggers pronounced flow separation and significant unsteady effects. Linear steering yields a smoother but the weakest motion response, with reduced rudder effectiveness and a noticeable lag effect. In contrast, trapezoidal steering maintains a stable flow field around the submarine, with uniformly concentrated vorticity distribution, ensuring smooth and safe motion and achieving a favorable balance between response speed and flow stability. The findings provide theoretical reference for research on submarine vertical-plane steering motion, rudder-angle control, and flow-field stability. Full article
(This article belongs to the Section Ocean Engineering)
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27 pages, 1221 KB  
Article
Optimization of Continuous Flow-Shop Scheduling Considering Due Dates
by Feifeng Zheng, Chunyao Zhang and Ming Liu
Algorithms 2025, 18(12), 788; https://doi.org/10.3390/a18120788 - 12 Dec 2025
Viewed by 431
Abstract
For a no-wait flow shop with continuous-flow characteristics, this study simultaneously considers machine setup times and rated processing speed constraints, aiming to minimize the sum of the maximum completion time and the maximum tardiness. First, lower bounds for the maximum completion time, the [...] Read more.
For a no-wait flow shop with continuous-flow characteristics, this study simultaneously considers machine setup times and rated processing speed constraints, aiming to minimize the sum of the maximum completion time and the maximum tardiness. First, lower bounds for the maximum completion time, the maximum tardiness, and the total objective function are developed. Second, a mixed-integer programming (MIP) model is formulated for the problem, and nonlinear elements are subsequently linearized via time discretization. Due to the computational complexity of the problem, two algorithms are proposed: a heuristic algorithm with fixed machine links and greedy rules (HAFG) and a genetic algorithm based on altering machine combinations (GAAM) for solving large-scale instances. The Earliest Due Date (EDD) rule is used as baselines for algorithmic comparison. To better understand the behaviors of the two algorithms, we observe the two components of the objective function separately. The results show that, compared with the EDD rule and GAAM, the HAFG algorithm tends to focus more on optimizing the maximum completion time. The performance of both algorithms is evaluated using their relative deviations from the developed lower bounds and is compared against the EDD rule. Numerical experiments demonstrate that both HAFG and GAAM significantly outperform the EDD rule. In large-scale instances, the HAFG algorithm achieves a gap of about 4%, while GAAM reaches a gap of about 3%, which is very close to the lower bound. In contrast, the EDD rule shows a deviation of about 10%. Combined with a sensitivity analysis on the number of machines, the proposed framework provides meaningful managerial insights for continuous-flow production environments. Full article
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21 pages, 4822 KB  
Article
Effects of Diameter and Aspect Ratios on Particle Separation Efficiency in Hydrocyclones
by Seunggi Choi, Wontak Choi, Dongmin Shin, Seongyool Ahn and Yonmo Sung
Processes 2025, 13(12), 3980; https://doi.org/10.3390/pr13123980 - 9 Dec 2025
Viewed by 366
Abstract
Hydrocyclones are widely used for solid–liquid separation, but their performance is highly sensitive to the geometric design. Previous studies often focused on individual structural parameters; however, the combined effects of the vortex finder diameter and aspect ratios on the internal flow field and [...] Read more.
Hydrocyclones are widely used for solid–liquid separation, but their performance is highly sensitive to the geometric design. Previous studies often focused on individual structural parameters; however, the combined effects of the vortex finder diameter and aspect ratios on the internal flow field and particle separation behavior remain insufficiently clarified. This study conducted three-dimensional numerical simulations using the realizable k-ε turbulence model, combined with the discrete phase model. The particle size distribution behaves according to the Rosin–Rammler function. Seven different geometries were evaluated under identical operating conditions to systematically investigate how the diameter and aspect ratios influence the internal vortex structures and separation behavior. A decrease in the diameter ratio enhances the dominance of the outward centrifugal forces, which increases the downward discharge of coarse particles but also results in greater liquid entrainment through the underflow. Conversely, larger diameter ratios strengthen the secondary vortex and promote upward flow. However, this also leads to decreased recovery of fine particles due to weakened centrifugal action. Adjusting the aspect ratio effectively mitigates these tradeoffs. Increasing the cone length enhances the residence time, stabilizes the upward vortex, and improves the separation of fine particles. Although the overall separation performance shows diminishing returns beyond a certain aspect-ratio threshold, the recovery of fine particles continues to improve. The results reveal that a balance between centrifugal and drag forces is essential, which is achieved through coordinated control of the vortex finder diameter and cone geometry. This balance is critical for maintaining stable flow fields and high efficiency in fine-particle removal. The findings provide practical design guidance for hydrocyclones, particularly in applications that require enhanced recovery of fine particles and stable multiphase flow behavior. Full article
(This article belongs to the Section Separation Processes)
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