Droplet Microfluidic-Based Systems: Fundamentals, Applications, and Future Directions

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B:Biology and Biomedicine".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 115

Special Issue Editors


E-Mail Website
Guest Editor
Department of Mechanical Engineering, University of Hong Kong, Hong Kong 999077, China
Interests: droplets; microfluidics; complex coacervates; DNA/RNA aptamers

E-Mail Website
Guest Editor
School of Biomedical Engineering, Shenzhen University, Shenzhen 518060, China
Interests: microfluidics; microscale interfacial phenomena; in vitro diagnostics

Special Issue Information

Dear Colleagues,

Droplet microfluidics has emerged as a powerful platform for a wide range of biochemical and industrial applications. The small spatial scales and high surface-to-volume ratios inherent to droplet-based systems offer unique advantages, including precise control of reagent volumes, well-defined reaction conditions, rapid mixing, enhanced interfacial effects, and high-throughput capabilities. These systems can facilitate biochemical reactions that are challenging to achieve in bulk phases. Over the past two decades, droplet microfluidics-based systems have been extensively investigated and applied in fields such as high-throughput screening, 3D printing, and wearable electronics. As we enter the middle of the fourth decade in the history of microfluidics, new knowledge, concepts, and technologies continue to emerge. For example, the development of artificial intelligence is paving the way for more advanced and sensitive droplet microfluidics-based systems.

This Special Issue, entitled “Droplet Microfluidic-Based Systems: Fundamentals, Applications, and Future Directions”, will highlight the latest fundamental studies and innovative applications in droplet microfluidics. We welcome submissions in the form of research papers, short communications, and review articles. Topics of interest include, but are not limited to, the following:

  1. Fundamental understanding of flow manipulations in droplet microfluidics-based systems;
  2. Designs, fabrications and applications of droplet microfluidics-based systems;
  3. High-throughput droplet microfluidics-based systems for various applications and processes;
  4. New concepts and technologies integrated into droplet microfluidics-based systems.

In addition, we welcome submissions regarding the latest early-stage biological or chemical applications potentially empowered by droplet microfluidics-based systems. A thorough discussion on how droplet microfluidics-based systems can improve these applications is required.

We look forward to receiving your submissions.

Sincerely,

Dr. Wei Guo
Dr. Yage Zhang
Guest Editors

Manuscript Submission Information

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Keywords

  • microfluidics
  • droplet manipulations
  • high-throughput screening
  • microfabrications
  • biochemical assays
  • directed evolution

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This special issue is now open for submission.
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