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Review

9 Citations

3,344 Views

10 Pages

Circulating Tumour DNA and Its Prognostic Role in Management of Muscle Invasive Bladder Cancer: A Narrative Review of the Literature

Konstantinos Kapriniotis,
Lazaros Tzelves,
Lazaros Lazarou,
Maria Mitsogianni and
Iraklis Mitsogiannis

Biomedicines2024, 12(4), 921;https://doi.org/10.3390/biomedicines12040921

21 April 2024

Current management of non-metastatic muscle invasive bladder cancer (MIBC) includes radical cystectomy and cisplatin-based neoadjuvant chemotherapy (NAC), offers a 5-year survival rate of approximately 50% and is associated with significant toxicitie...

(This article belongs to the Special Issue Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment)

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Review

373 Views

34 Pages

Acquired Chemoresistance in Colorectal Cancer: Therapy-Induced Signalling Adaptation, Cellular Plasticity and Mechanism-Guided Therapeutic Strategies

Dorota Bartusik-Aebisher,
Izabella Wilk,
Blassan P. George and
David Aebisher

Cells2026, 15(19), 1776;https://doi.org/10.3390/cells15191776

29 September 2026

The effectiveness of chemotherapy in colorectal cancer (CRC) is significantly reduced by acquired chemoresistance to 5-fluorouracil (5-FU), oxaliplatin and irinotecan. This structured narrative review synthesises mechanistic, preclinical, translation...

(This article belongs to the Special Issue Cell Signaling of Cancer Therapy)

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