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7 Results Found

  • Article
  • Open Access
4 Citations
2,290 Views
11 Pages

Effect of Nanosecond Pulsed Currents on Directions of Cell Elongation and Migration through Time-Lapse Analysis

  • Hayato Tada,
  • Satoshi Uehara,
  • Chia-Hsing Chang,
  • Ken-ichi Yano and
  • Takehiko Sato

14 February 2023

It is generally known that cells elongate perpendicularly to an electric field and move in the direction of the field when an electric field is applied. We have shown that irradiation of plasma-simulated nanosecond pulsed currents elongates cells, bu...

  • Article
  • Open Access
10 Citations
3,544 Views
17 Pages

30 September 2021

Polymer electrolytes based on agarose dissolved in DMSO solvent complexed with different weight percentages of Mg(NO3)2 ranging from 0 to 35 wt% were prepared using a solution casting method. Electrochemical impedance spectroscopy (EIS) was applied t...

  • Article
  • Open Access
7 Citations
3,587 Views
22 Pages

Adult Multipotent Cardiac Progenitor-Derived Spheroids: A Reproducible Model of In Vitro Cardiomyocyte Commitment and Specification

  • Mariangela Scalise,
  • Fabiola Marino,
  • Luca Salerno,
  • Nunzia Amato,
  • Claudia Quercia,
  • Chiara Siracusa,
  • Andrea Filardo,
  • Antonio Chiefalo,
  • Loredana Pagano and
  • Eleonora Cianflone
  • + 6 authors

5 July 2023

Background: Three-dimensional cell culture systems hold great promise for bridging the gap between in vitro cell-based model systems and small animal models to study tissue biology and disease. Among 3D cell culture systems, stem-cell-derived spheroi...

  • Article
  • Open Access
448 Views
20 Pages

A Bio-Inspired Artificial Nerve Simulator for Ex Vivo Validation of Implantable Neural Interfaces Equipped with Plug Electrodes

  • Daniel Mihai Teleanu,
  • Octavian Narcis Ionescu,
  • Carmen Aura Moldovan,
  • Marian Ion,
  • Adrian Tulbure,
  • Eduard Franti,
  • David Catalin Dragomir,
  • Silviu Dinulescu,
  • Bianca Mihaela Boga and
  • Mirela Petruta Suchea
  • + 10 authors

The development of implantable neural interfaces is essential for enabling bidirectional communication between the nervous system and prosthetic devices, yet their evaluation still relies primarily on in vivo models which are costly, variable, and et...

  • Article
  • Open Access
23 Citations
5,633 Views
15 Pages

Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes

  • Ka Cheong Lee,
  • Rebecca L. Swan,
  • Zbyslaw Sondka,
  • Kay Padget,
  • Ian G. Cowell and
  • Caroline A. Austin

DNA topoisomerase II (TOP2) activity involves a normally transient double-strand break intermediate in which the enzyme is coupled to DNA via a 5′-phosphotyrosyl bond. However, etoposide and other topoisomerase drugs poison the enzyme by stabil...

  • Article
  • Open Access
2 Citations
2,842 Views
13 Pages

Cutinase from Fusarium solani pisi is an enzyme that bridges functional properties between lipases and esterases, with applications in detergents, food processing, and the synthesis of fine chemicals. The purification procedure of recombinant cutinas...

  • Article
  • Open Access
1,277 Views
13 Pages

High-Resolution Analysis of DNA Electrophoretic Separations via Digital Image Processing

  • Jing Yang,
  • Tengfei Zhang,
  • Bo Yang,
  • Jiahe Liu,
  • Zhenqing Li and
  • Yoshinori Yamaguchi

29 October 2025

Compared with capillary electrophoresis (CE), gel electrophoresis (GE) is a traditional method for the analysis of nucleic acids because of its low cost, although the operation process is complicated. The electropherogram from CE can offer more infor...