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Article

1,388 Views

22 Pages

Identification of Bioactive Compounds in Warburgia salutaris Leaf Extracts and Their Pro-Apoptotic Effects on MCF-7 Breast Cancer Cells

Lebogang Valentia Monama,
Daniel Lefa Tswaledi,
Tshisikhawe Masala Hadzhi,
Makgwale Sharon Mphahlele,
Mopeledi Blandina Madihlaba,
Matlou Phineas Mokgotho,
Leshweni Jeremia Shai and
Emelinah Hluphekile Mathe

Int. J. Mol. Sci.2025, 26(16), 8065;https://doi.org/10.3390/ijms26168065

20 August 2025

The apoptotic mechanism is complex and involves many pathways. Defects can occur at any time along these pathways, resulting in malignant cell transformation and resistance to anticancer drugs. Collective efforts have made great progress in the imple...

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Article

28 Citations

4,395 Views

12 Pages

Iso-Mukaadial Acetate from Warburgia salutaris Enhances Glucose Uptake in the L6 Rat Myoblast Cell Line

Nontokozo Z. Msomi,
Francis O. Shode,
Ofentse J. Pooe,
Sithandiwe Mazibuko-Mbeje and
Mthokozisi B. C. Simelane

Biomolecules2019, 9(10), 520;https://doi.org/10.3390/biom9100520

22 September 2019

Diabetes mellitus (DM) is a chronic metabolic disorder which has become a major risk to the health of humankind, as its global prevalence is increasing rapidly. Currently available treatment options in modern medicine have several adverse effects. Th...

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Article

3 Citations

3,593 Views

19 Pages

The Utilization of Selected Threatened or Protected Plant Species; A Case of Limpopo Province, South Africa

Marula Rasethe,
Martin Potgieter and
Michèle Pfab

Sustainability2022, 14(3), 1073;https://doi.org/10.3390/su14031073

18 January 2022

In Limpopo Province, harvesting plants for herbal use by traditional health practitioners and ordinary people is an everyday practice. The study investigated the utilization of the following Threatened or Protected Plant-listed species (TOPS): Alepid...

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Article

1,443 Views

21 Pages

Plants Utilization and Perceptions in the Context of Novel Indigenous Food Spicing and Flavoring Among the Vhavenḓa People in the Vhembe Biosphere Reserve, South Africa

Mueletshedzi Manyaga,
Ncobile Pretty Mhlongo,
Maropeng Erica Matlala,
Nonhlanhla Prudence Lubisi,
Vhuhwavho Gelebe,
Christeldah Mkhonto,
Elizabeth Kola,
Wilfred Otang Mbeng,
Peter Tshepiso Ndhlovu and
Luambo Jeffrey Ramarumo
+ 4 authors

Plants2025, 14(13), 1962;https://doi.org/10.3390/plants14131962

26 June 2025

Local innovations regarding plant-derived spice and flavorant formulations and preparation techniques are mostly recorded nowhere and usually passed on generationally through word of mouth. This study aimed to inventory the utilization of plants and...

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Review

126 Citations

36,988 Views

36 Pages

Plant Extracts as Skin Care and Therapeutic Agents

Monika Michalak

Int. J. Mol. Sci.2023, 24(20), 15444;https://doi.org/10.3390/ijms242015444

22 October 2023

Natural ingredients have been used for centuries for skin treatment and care. Interest in the health effects of plants has recently increased due to their safety and applicability in the formulation of pharmaceuticals and cosmetics. Long-known plant...

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