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6 Results Found

  • Article
  • Open Access
11 Citations
3,305 Views
16 Pages

Putative Mitoviruses without In-Frame UGA(W) Codons: Evolutionary Implications

  • Andrés Gustavo Jacquat,
  • Martín Gustavo Theumer and
  • José Sebastián Dambolena

25 January 2023

Mitoviruses are small vertically transmitted RNA viruses found in fungi, plants and animals. Taxonomically, a total of 105 species and 4 genera have been formally recognized by ICTV, and recently, 18 new putative species have been included in a new p...

  • Article
  • Open Access
26 Citations
9,457 Views
18 Pages

The UGG Isoacceptor of tRNAPro Is Naturally Prone to Frameshifts

  • Howard B. Gamper,
  • Isao Masuda,
  • Milana Frenkel-Morgenstern and
  • Ya-Ming Hou

1 July 2015

Native tRNAs often contain post-transcriptional modifications to the wobble position to expand the capacity of reading the genetic code. Some of these modifications, due to the ability to confer imperfect codon-anticodon pairing at the wobble positio...

  • Review
  • Open Access
189 Citations
21,836 Views
22 Pages

20 November 2020

Tryptophan (Trp) holds a unique place in biology for a multitude of reasons. It is the largest of all twenty amino acids in the translational toolbox. Its side chain is indole, which is aromatic with a binuclear ring structure, whereas those of Phe,...

  • Article
  • Open Access
16 Citations
4,485 Views
16 Pages

Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons

  • Raffaella Melfi,
  • Patrizia Cancemi,
  • Roberta Chiavetta,
  • Viviana Barra,
  • Laura Lentini and
  • Aldo Di Leonardo

Cystic fibrosis (CF) is caused by mutations in the gene encoding the transmembrane conductance regulator (CFTR) protein. Some CF patients are compound heterozygous or homozygous for nonsense mutations in the CFTR gene. This implies the presence in th...

  • Article
  • Open Access
5 Citations
1,790 Views
13 Pages

Apostasia fujianica belongs to the genus Apostasia and is part of the basal lineage in the phylogenetic tree of the Orchidaceae. Currently, there are only ten reported complete mitochondrial genomes in orchids, which greatly hinders the understanding...

  • Article
  • Open Access
32 Citations
5,018 Views
20 Pages

22 April 2020

Bupleurum L. (Apiaceae) is a perennial and herbal genus, most species of which have high medicinal value. However, few studies have been performed using plastome data in this genus, and the phylogenetic relationships have always been controversial. I...