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4 Results Found

  • Review
  • Open Access
17 Citations
15,086 Views
15 Pages

A Chewable Cure “Kanna”: Biological and Pharmaceutical Properties of Sceletium tortuosum

  • Madira Coutlyne Manganyi,
  • Cornelius Carlos Bezuidenhout,
  • Thierry Regnier and
  • Collins Njie Ateba

28 April 2021

Sceletium tortuosum (L.) N.E.Br. (Mesembryanthemaceae), commonly known as kanna or kougoed, is an effective indigenous medicinal plant in South Africa, specifically to the native San and Khoikhoi tribes. Today, the plant has gained strong global attr...

  • Article
  • Open Access
3 Citations
15,228 Views
11 Pages

Effects of Zembrin® (Sceletium tortuosum) Supplementation on Mood, Soreness, and Performance Following Unaccustomed Resistance Exercise: A Pilot Study

  • Angela R. Berry,
  • Haley N. Langley,
  • Rebecca R. Rogers,
  • Courteney L. Benjamin,
  • Tyler D. Williams and
  • Christopher G. Ballmann

The purpose of this study was to investigate acute Zembrin® (Sceletium tortuosum) supplementation on muscle soreness, markers of muscle damage, mood, and exercise performance following unaccustomed resistance exercise. Untrained females (n = 16) were...

  • Article
  • Open Access
3,578 Views
38 Pages

4 July 2025

Sceletium tortuosum (ST) induces antidepressant and anxiolytic effects, purportedly by monoamine regulation, anti-inflammatory and antioxidant properties, and phosphodiesterase 4 (PDE4) inhibition. These multimodal actions have not been demonstrated...

  • Feature Paper
  • Review
  • Open Access
30 Citations
36,120 Views
51 Pages

Pharmacology of Herbal Sexual Enhancers: A Review of Psychiatric and Neurological Adverse Effects

  • Pietro Brunetti,
  • Alfredo Fabrizio Lo Faro,
  • Anastasio Tini,
  • Francesco Paolo Busardò and
  • Jeremy Carlier

14 October 2020

Sexual enhancers increase sexual potency, sexual pleasure, or libido. Substances increasing libido alter the concentrations of specific neurotransmitters or sex hormones in the central nervous system. Interestingly, the same pathways are involved in...