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7 Results Found

  • Article
  • Open Access
2 Citations
2,475 Views
14 Pages

Background and aims: Thromboangiitis obliterans (TAO), also known as Buerger’s disease, is a rare vasculitis. Observational epidemiology studies have suggested a relationship between the gut microbiota and TAO. However, due to confounding facto...

  • Article
  • Open Access
50 Citations
5,160 Views
14 Pages

Indole Acetic Acid Exerts Anti-Depressive Effects on an Animal Model of Chronic Mild Stress

  • Ying Chen,
  • Peijun Tian,
  • Zheng Wang,
  • Ruili Pan,
  • Kexin Shang,
  • Gang Wang,
  • Jianxin Zhao and
  • Wei Chen

25 November 2022

Indole acetic acid (IAA), an intestinal bacteria-derived tryptophan metabolite, has been detected at abnormal concentrations in the cerebrospinal fluid and urine of depressed individuals. The effects of such altered IAA concentrations on mood regulat...

  • Article
  • Open Access
10 Citations
3,719 Views
14 Pages

Buckwheat Flour and Its Starch Prevent Age-Related Cognitive Decline by Increasing Hippocampal BDNF Production in Senescence-Accelerated Mouse Prone 8 Mice

  • Shigeru Katayama,
  • Chizuru Okahata,
  • Masashi Onozato,
  • Takaaki Minami,
  • Masanaga Maeshima,
  • Kazuaki Ogihara,
  • Shinya Yamazaki,
  • Yuta Takahashi and
  • Soichiro Nakamura

29 June 2022

Buckwheat is an important pseudo-cereal crop worldwide. This study investigated whether long-term administration of buckwheat can suppress age-related cognitive decline in senescence-accelerated mouse prone 8 (SAMP8) mice. For 26 weeks, 18-week-old m...

  • Article
  • Open Access
8 Citations
3,042 Views
16 Pages

Tartary Buckwheat (Fagopyrum tataricum) Ameliorates Lipid Metabolism Disorders and Gut Microbiota Dysbiosis in High-Fat Diet-Fed Mice

  • Ang Li,
  • Jin Wang,
  • Yuanyifei Wang,
  • Bowei Zhang,
  • Zhenjia Chen,
  • Junling Zhu,
  • Xiaowen Wang and
  • Shuo Wang

29 September 2022

Jinqiao II, a newly cultivated variety of tartary buckwheat (Fagopyrum tataricum), has been reported to exhibit a higher yield and elevated levels of functional compounds compared to traditional native breeds. We aimed to investigate the potential of...

  • Article
  • Open Access
8 Citations
12,536 Views
16 Pages

The Microbiome, Epigenome, and Diet in Adults with Obesity during Behavioral Weight Loss

  • Emily B. Hill,
  • Iain R. Konigsberg,
  • Diana Ir,
  • Daniel N. Frank,
  • Purevsuren Jambal,
  • Elizabeth M. Litkowski,
  • Ethan M. Lange,
  • Leslie A. Lange,
  • Danielle M. Ostendorf and
  • Jared J. Scorsone
  • + 8 authors

16 August 2023

Obesity has been linked to the gut microbiome, epigenome, and diet, yet these factors have not been studied together during obesity treatment. Our objective was to evaluate associations among gut microbiota (MB), DNA methylation (DNAme), and diet pri...

  • Article
  • Open Access
15 Citations
4,785 Views
17 Pages

Raw Milk-Induced Protection against Food Allergic Symptoms in Mice Is Accompanied by Shifts in Microbial Community Structure

  • Suzanne Abbring,
  • Phillip A. Engen,
  • Ankur Naqib,
  • Stefan J. Green,
  • Johan Garssen,
  • Ali Keshavarzian and
  • Betty C. A. M. van Esch

The mechanism underlying the allergy-protective effects of raw cow’s milk is still unknown, but the modulation of the gut microbiome may play a role. The effects of consuming raw cow’s milk or processed milk on fecal microbial communities were theref...

  • Systematic Review
  • Open Access
55 Citations
6,800 Views
32 Pages

13 October 2023

This systematic review aims to provide a comprehensive understanding of the current literature regarding gut microbiota composition in patients with Parkinson’s disease (PD) and Alzheimer’s disease (AD) compared to healthy controls. To id...