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7 Results Found

  • Article
  • Open Access
1,414 Views
22 Pages

Poria cocos extract attenuates MK-801-induced hyperactivity via RhoA/ROCK1 pathway modulation in mice. Background/Objectives: Poria cocos (P. cocos), a traditional East Asian medicinal mushroom, serves as a medicine and nutritional supplement, has be...

  • Article
  • Open Access
10 Citations
6,835 Views
9 Pages

1 October 2023

Background: Since the outbreak of the pandemic started, an increase in the number of sleep disorders, including insomnia and poor sleep quality, has been seen. The pattern will probably continue. Methods: This study focuses on the preparation and cli...

  • Article
  • Open Access
30 Citations
4,451 Views
15 Pages

1 February 2023

In this study, a response surface methodology and an artificial neural network coupled with a genetic algorithm (RSM-ANN-GA) was used to predict and estimate the optimized ultrasonic-assisted extraction conditions of Poria cocos. The ingredient yield...

  • Article
  • Open Access
14 Citations
3,645 Views
20 Pages

A Comparative Study of Serum Pharmacochemistry of Kai-Xin-San in Normal and AD Rats Using UPLC-LTQ-Orbitrap-MS

  • Lin Yang,
  • Jian Liang,
  • Qin Zheng,
  • Lifen Zhou,
  • Yongchang Xiong,
  • Huijuan Wang and
  • Jinbin Yuan

26 December 2022

Kai-Xin-San (KXS) is a classic formula for the treatment of Alzheimer’s disease (AD). KXS has been widely used to treat emotional diseases; however, its active components remain unknown. There have been some reports about the efficacy and metab...

  • Article
  • Open Access
32 Citations
9,122 Views
17 Pages

In Vitro Study on Anti-Hepatitis C Virus Activity of Spatholobus suberectus Dunn

  • Shao-Ru Chen,
  • An-Qi Wang,
  • Li-Gen Lin,
  • Hong-Cong Qiu,
  • Yi-Tao Wang and
  • Ying Wang

15 October 2016

Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, i...

  • Article
  • Open Access
14 Citations
4,687 Views
15 Pages

Determination of Cultivation Regions and Quality Parameters of Poria cocos by Near-Infrared Spectroscopy and Chemometrics

  • Jing Xie,
  • Jianhua Huang,
  • Guangxi Ren,
  • Jian Jin,
  • Lin Chen,
  • Can Zhong,
  • Yuan Cai,
  • Hao Liu,
  • Rongrong Zhou and
  • Shuihan Zhang
  • + 1 author

21 March 2022

Poria cocos (PC) is an important fungus with high medicinal and nutritional values. However, the quality of PC is heavily dependent on multiple factors in the cultivation regions. Traditional methods are not able to perform quality evaluation for thi...

  • Article
  • Open Access
25 Citations
7,413 Views
20 Pages

5 November 2021

Paeonia lactiflora Pallas (PL) and Poria cocos Wolf (PC) have been traditionally used to treat inflammatory diseases reported in Dongui Bogam and Shen Nong Ben Cao Jing, traditional medical books in Korean and China, respectively. We determined the e...