Search Results (1,685)

Perceived safety strongly shapes how residents use and experience their neighborhoods, yet evidence on how spatial and social factors interact in rapidly urbanizing Asian cities remains limited. This study investigates the role of natural surveillance, spatial connectivity, and perceived incivilities in shaping residents’ perceived safety in Bayan Baru, Malaysia, with fear of crime examined as a key mediating factor. A face-to-face survey of 300 adults measured five constructs: natural surveillance, spatial connectivity, perceived incivilities, fear of crime, and perceived safety. Data were analyzed using PLS-SEM in SmartPLS 4.0, supported by bootstrapping and predictive relevance tests. Results showed that natural surveillance and spatial connectivity increased perceived safety both directly and indirectly by reducing fear, while perceived incivilities undermined perceived safety through heightened fear. Additional interdependencies indicated that spatial connectivity strengthened natural surveillance, which in turn reduced perceived incivilities and reinforced perceived safety, though connectivity alone did not directly reduce incivilities. Mediation analysis confirmed fear of crime as a central psychological bridge linking environmental cues to safety evaluations. These findings highlight how the interplay of visibility, connectivity, and disorder shape perceived safety in Malaysian neighbourhood settings. Interventions should combine design improvements, maintenance of public space, and community engagement to reduce fear and strengthen everyday confidence in neighborhood safety. Full article

In globalized markets, traditional Chinese furniture must strike a balance between cultural authenticity and modern consumer appeal. This study introduced the first comprehensive scale to measure Confucian–Daoist value expressions in Ming-style chair design for marketing applications. Through surveys conducted across 31 Chinese provinces (pilot sample size = 85; formal sample size = 440) and extensive literature analysis, six key cultural dimensions influencing consumer preferences were identified: respect for tradition, face, familism, respect for authority, the doctrine of the mean, and the nature/non-action. Building on these findings, this study proposes the first multidimensional framework for assessing Confucian and Daoist values in Ming-style chair design, offering an 18-item scale as a quantifiable tool to support the sustainable innovation of cultural heritage. The scale enables marketers and designers to detect regional and historical variations in cultural value preferences, thereby facilitating targeted positioning strategies that preserve authentic cultural expression while resonating with specific consumer segments. Full article

Background/Objectives: Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infection in young children, especially during infancy, resulting in substantial morbidity and mortality. Methods: Acknowledging the real-world evidence on RSV immunization, the College of Pediatrics, Academy of Medicine of Malaysia, has appointed an expert panel to develop a position paper on recommendations for infant and/or maternal vaccination against childhood RSV, specifically in the Malaysian context with year-round RSV activity. Results: Recognizing the potential constraints and limitations in the implementation process, the expert panel recommends targeted immunization with long-acting RSV monoclonal antibody (mAb) for high-risk infants as a pragmatic first step, with subsequent scale-up to universal immunization of infants when resources permit. Conclusions: Immunization is the most effective strategy to prevent RSV-related lower respiratory tract infection in childhood. Year-round maternal vaccination between 28 and 36 weeks’ gestation, combined with immunization at six months for all infants, may potentially circumvent the unclear seasonality. Full article

Bats provide essential ecosystem services, particularly in regulating insect populations within agricultural landscapes. However, research on bat–insect interactions in Malaysian rice fields remains limited. This study examined bat diversity and insect abundance in the rice field area of Gunung Keriang, Kedah, using two harp traps, two mist nets and a light trap at three selected sites. A total of 2499 bats representing 27 species were captured, alongside 161,539 insects from 11 orders. Rhinolophus pusillus was the dominant bat species across all seasons. During the dry season, Chilo polychrysus (stem borer) was the dominant insect pest, whereas Nilaparvata lugens (brown planthopper) prevailed during the wet season. Insects from the order Coleoptera, dominant in the dry season, are likely consumed by larger bat species with stronger bite forces. Bat foraging activity peaked concurrently with insect emergence, corresponding to periods of high food availability. Statistical analysis revealed significant associations between bat activity, temperature, and rainfall, but not insect abundance. These findings underscore the ecological importance of bats as natural pest regulators in rice field ecosystems and highlight their potential role in promoting sustainable, ecosystem-based agricultural management. Full article

Urban stray cats are often associated with ectoparasites and zoonotic pathogens due to their unsanitary living conditions and lack of veterinary care. Fleas, especially Ctenocephalides spp., are competent vectors of Bartonella spp., a genus of emerging bacterial pathogens with both public health and veterinary relevance. This study investigated the presence of Bartonella DNA in ectoparasitic fleas infesting stray cats in various urban habitats within the Klang Valley, Malaysia. A total of 204 fleas were collected from 89 stray cats. Fleas were identified morphologically using established taxonomic keys under a light microscope and further validated through PCR amplification of the mitochondrial cytochrome c oxidase subunit I (cox1) gene. Detection of Bartonella spp. was conducted by targeting the citrate synthase (gltA) gene. All fleas were confirmed as Ctenocephalides felis, with an infestation prevalence of 39.33% among the cats sampled. Of 118 C. felis specimens tested, 86.44% were positive for Bartonella DNA, one of the highest worldwide and significantly surpassing previous Malaysian reports. Sequencing of 12 positive samples showed identities with B. claridgeiae (58.3%), B. henselae (25.0%), an uncultured Bartonella species (8.3%) and a Bartonella isolate from a dog in Chile (8.3%). These results highlight the significant presence of Bartonella, causative agent of cat-scratch disease in stray cats, emphasizing their potential role as urban reservoirs and vectors. The findings underscore the need for ectoparasite surveillance and zoonotic pathogen control as integral components of stray animal management in Malaysia’s urban settings. Full article

Unmanned aerial vehicles (UAVs) are increasingly utilized across civilian and defense sectors due to their versatility, efficiency, and cost-effectiveness. However, their operational endurance remains constrained by limited onboard energy storage. Recent research has focused on electric propulsion systems integrated with hybrid energy sources, particularly the combination of solar cells and advanced battery technologies to overcome this limitation. This review presents a comprehensive analysis of the latest advancements in electric propulsion architecture, solar-based power integration, and hybrid energy management strategies for UAVs. Key components, including motors, electronic speed controllers (ESCs), propellers, and energy storage systems, are examined alongside emerging technologies such as wireless charging and flexible photovoltaic (PV) materials. Power management techniques, including maximum power point tracking (MPPT) and intelligent energy control algorithms, are also discussed in the context of long-endurance missions. Challenges related to energy density, weight constraints, environmental adaptability, and component integration are highlighted, with insights into potential solutions and future directions. The findings of this review aim to guide the development of efficient, sustainable, and high-endurance UAV platforms leveraging electric-solar hybrid propulsion systems. Full article

Background: Congenital disorders of glycosylation (CDG) are rare inborn errors of metabolism with multisystemic manifestations. SSR4-CDG is an ultra-rare X-linked subtype caused by pathogenic variants in SSR4, a component of the translocon-associated protein (TRAP) complex essential for protein translocation and N-glycosylation. Case presentation: We report a two-year-old Malaysian male presenting with global developmental delay, central hypotonia, microcephaly with complete agenesis of the corpus callosum, recurrent infections, bilateral vesicoureteral reflux, and failure to thrive. Growth parameters (weight, length, and head circumference) were persistently below the expected percentiles, indicating postnatal growth restriction. Initial metabolic and biochemical investigations for global developmental delay were unremarkable, apart from mild hyperammonemia. Transferrin isoform analysis demonstrated a type I CDG pattern, raising suspicion of a glycosylation defect. Results: Transferrin glycopeptide LC–MS/MS showed impaired N-glycan occupancy at both glycosylation sites (Asn432 and Asn630), with reduced fully sialylated glycoforms and increased non-glycosylated peptides. Targeted metabolomics using triple quadrupole LC–MS/MS revealed systemic abnormalities, including elevated arginine and phenylalanine, reduced glutamate, increased lysophosphatidylcholine (C24:0-LPC), and generalized depletion of free and acylcarnitines. Whole-exome sequencing identified a novel hemizygous SSR4 variant (c.98del; p.Pro33LeufsTer23) on the X chromosome, predicted to produce a truncated, nonfunctional protein. Conclusions: This is the first Malaysian patient with SSR4-CDG, comprehensively characterized using a multi-omics diagnostic workflow. The integration of glycoproteomics, metabolomics, and exome sequencing provided a detailed biochemical fingerprint that expands the clinical, genetic, and metabolic spectrum of SSR4-CDG and demonstrates the diagnostic and translational value of multi-omics approaches in inborn errors of metabolism. Full article

Based on the Malaysian market, this study investigates the connection between ESG (environmental, social, and governance) disclosure performance and audit fees and examines whether institutional ownership moderates this relationship. The sample of this study comprises 323 firm-year observations collected from 49 Malaysian publicly listed companies covering 2012 to 2020. Panel data regression is employed to test the hypotheses. The findings indicate a significant positive relationship between ESG disclosure performance and audit fees, suggesting that auditors perceive ESG reporting as increasing audit complexity and risk. Further, institutional ownership strengthens this positive relationship, indicating that sophisticated investors’ monitoring roles lead to more thorough auditing of ESG disclosures. Our primary contribution is resolving mixed findings in prior literature by identifying institutional ownership as a key moderating variable. The findings offer critical insights for Malaysian regulators in designing the ESG verification framework and help companies and investors better understand audit cost drivers. This study highlights the real-world impact of institutional shareholders on corporate governance and raises market awareness of how auditors respond to sustainability disclosures. Full article

This study aims to examine the antecedents influencing corporate social responsibility (CSR) practices in Malaysian oil and gas companies, addressing the limited empirical research in this sector. Data were collected through a survey of 65 managerial-level representatives, including CEOs and senior management, from Malaysian oil and gas companies. IBM SPSS (Version 28) and SmartPLS (Version 3.3) were used to analyse the data and test the proposed relationships using PLS-SEM. The results reveal that stakeholder pressure has a positive and significant relationship with CSR practices in the oil and gas industry. This indicates that legitimacy-driven motivations play a key role in CSR adoption. Furthermore, CSR practices are found to enhance corporate reputation and competitive advantage. The findings highlight the importance for managers to recognize stakeholder expectations as a major driver of CSR adoption and to leverage CSR initiatives to strengthen organizational reputation and competitiveness. This study contributes to the limited body of knowledge on CSR practices within Malaysia’s oil and gas industry by providing empirical evidence of the factors influencing CSR implementation and its organizational outcomes. Full article

The Malaysian palm oil industry faces significant environmental challenges from Palm Oil Mill Effluent (POME), a high-strength wastewater. Conventional ponding systems for POME treatment are inefficient, land-intensive, and major sources of methane emissions. Zero Liquid Discharge (ZLD) presents a transformative solution by eliminating effluent discharge while recovering water, energy, and nutrients, aligning with circular economy principles. This review provides a critical techno-economic and Environmental, Social, and Governance (ESG) assessment of ZLD integration for POME management in Malaysia. A key contribution is the novel framework for categorizing ZLD integration at three strategic points in the treatment process, supported by comparative quantitative data on performance and costs. The review thoroughly examines hybrid technologies and delivers an in-depth analysis of the Social and Governance implications of ZLD integration, alongside its Environmental benefits, demonstrating ZLD’s role in meeting regulatory demands and advancing the United Nations Sustainable Development Goals (SDGs). The paper concludes by exploring future directions, including digital twin integration and novel financing, positioning ZLD as a strategic imperative for the industry’s long-term viability and global competitiveness. Full article

In response to the increasing global emphasis on sustainability, electric vehicles (EVs) have emerged as promising alternative vehicles. Grounded in the Value–Attitude–Behaviour (VAB) model and the Theory of Planned Behaviour (TPB), this study investigates Malaysian consumers’ intention to choose EVs as their preferred mode of transportation. Specifically, the study explores the relationships between price, maintenance cost, infrastructure readiness, consumer attitudes, and purchase intention. Moreover, it examines the mediating role of consumer attitude in the relationships between price, maintenance cost, and infrastructure readiness with the intention to purchase EVs. A total of 252 respondents from Malaysia participated in the study, with data collected using a proportionate stratified sampling technique. Out of the seven hypotheses tested, six were supported. The findings reveal that maintenance cost, infrastructure readiness, and attitude have significant positive relationships with consumers’ intention to purchase EVs. The results further indicate that consumer attitude mediates the relationship between price, maintenance cost, and infrastructure readiness with the intention to purchase EVs. Theoretically, this study contributes to the existing body of knowledge by developing a framework that integrates value-based antecedents with attitudinal and behavioural outcomes. Practically, the findings provide valuable insights for marketers and policymakers to formulate effective strategies and policies that can accelerate EV adoption. Full article

Background: Regular physical activity benefits people of all ages by enhancing both mental and physical health, whereas inactivity raises the risk of noncommunicable diseases (NCDs) like cardiovascular diseases, cancer, and diabetes, which can result in premature death. The objective of this cross-sectional study was to determine the prevalence and associated factors of physical inactivity among adults in Malaysia. Methods: Data on physical inactivity were extracted from the 2023 National Health and Morbidity Survey (NHMS), conducted from July to September 2023 among adults aged 18 and above across all states of Malaysia. Physical activity was assessed using the Global Physical Activity Questionnaire, with individuals classified as inactive if they did not achieve at least 600 metabolic equivalents of task (MET) minutes per week. Logistic regression was used to identify factors associated with physical inactivity. Results: A total of 10,858 out of 13,616 respondents participated in the study, resulting in a response rate of 79.7%. The overall rate of physical inactivity was 29.9%. The multivariable logistic regression analysis showed that physical inactivity was significantly higher among urban residents (aOR 1.42; 95% CI: 1.16, 1.75), individuals who were single/divorced/widowed (aOR 1.16; 95% CI: 1.01, 1.33), those not working (aOR 1.61; 95% CI: 1.24, 2.09), and those with sedentary time exceeding four hours per day (aOR 1.46; 95% CI: 1.20, 1.76). Inactivity was also more likely among individuals with diabetes (aOR 1.17; 95% CI: 1.00, 1.37) or disabilities (aOR 1.67; 95% CI: 1.39, 2.02). Conclusions: About one-third of Malaysian adults are physically inactive, with higher rates among urban residents, single/divorced/widowed, those not working, those with extended sedentary time, diabetes, or disabilities. Targeted interventions are needed to encourage behaviour change, foster active urban design, and strengthen policies that support active lifestyles. Full article

The Malaysian Apis cerana honey (ACH) was analysed for its physicochemical characteristics, including moisture, Baume, Brix analysis (total soluble solids and total soluble sugars), sugar profiling (fructose, glucose, sucrose, maltose, and lactose), total ash, pH, free acidity, electrical conductivity, colour analysis, and choline content. The inhibitory effects of pancreatic lipase, α-amylase, and α-glucosidase activities were also assessed. Results indicated that the sum of fructose and glucose, sucrose, and electrical conductivity were all within the recommended range following the requirements of international standards. The maximum levels were, nevertheless, exceeded by moisture, free acidity and total ash. The ACH showed potential as an anti-obesity and anti-diabetic agent by inhibiting pancreatic lipase by up to 43.4% at 0.063 mg/mL, α-amylase by up to 70% at 7.0 mg/mL and α-glucosidase by up to 67.6% at 100 mg/mL, respectively. The percentage inhibition of α-glucosidase by undiluted ACH and deionised water extract at different temperatures (4.8 ± 0.5 °C, 27 ± 0.5 °C, and 40 ± 0.5 °C) was comparable, suggesting that temperatures had little effect on the degree of inhibition. Full article

Chronic stress is a key risk factor for depression and metabolic dysfunction, widely mediated through oxidative stress and inflammatory pathways. Natural products such as honey are increasingly investigated for their potential to attenuate stress-induced pathophysiological changes. This study evaluated the protective effects of Malaysian Acacia honey (AH) on glucose regulation, oxidative damage, histopathological alterations, and pro-inflammatory cytokine expression in stress-induced rats. Male Sprague–Dawley rats (n = 42) were subjected to chronic unpredictable mild stress and supplemented with AH, amitriptyline (AMT), or their combination for 28 days. Blood glucose levels, erythrocyte hemolysis, histological changes in liver and kidney, and expression of IL-1β and TGF-β1 in ileum, caecum, and hypothalamus were assessed. Data were reported as mean and standard error of mean (SEM) after three or more independent experiments had been conducted. The data were analyzed using a paired-t-test or a one-way or two-way analysis of variance (ANOVA) and considered significant if p < 0.05. Stress markedly elevated glucose levels (7.97 ± 0.20 mmol/L), increased hemolysis (14.30% ± 2.96), and induced hepatic (cytoplasmic vacuolation, 1.40 ± 0.25; cell lining absent, 1.20 ± 0.37) and renal lesions (dilated intertubular capillaries, 1.40 ± 0.51; inflammation, 2.20 ± 0.20), accompanied by upregulation of IL-1β (1.27-fold ± 0.20) and TGF-β1 (1.00-fold ± 0.08). Supplementation with AH significantly reduced hyperglycemia, inhibited hemolysis, ameliorated tissue damage, and downregulated pro-inflammatory cytokines. Combination therapy with AH and AMT produced the most significant improvements near to normal level, suggesting synergistic benefits. These findings highlight the therapeutic potential of AH as a natural adjunct in managing stress-related metabolic and inflammatory disturbances. Full article

Ageing is often accompanied by gut microbiota alterations that contribute to dysbiosis—a recognised hallmark of ageing and a risk factor for neurodegenerative diseases. Probiotic interventions offer a promising approach to restore microbial homeostasis. This preliminary study explored the potential modulatory effects of Malaysian kefir water, a Lactobacillus-enriched fermented beverage with previously reported antioxidant and neuroprotective properties in D-galactose-induced ageing mice. Kefir water was administered as both a pre-treatment and co-treatment, and gut microbiota changes were assessed using 16S rRNA metagenomic sequencing of faecal samples. Alpha and beta diversity analyses showed a stable microbial diversity across treatments. However, preliminary descriptive trends suggested that kefir water may influence specific bacterial populations. Increases were observed in Muribaculaceae and Lactobacillaceae, along with apparent decreases in Lachnospiraceae and Prevotellaceae. Both kefir treatments tended to increase the abundance of Ligilactobacillus, with the co-treatment group appearing to restore the Firmicutes/Bacteroidota ratio toward control levels, while the pre-treatment group showed a tendency to further reduce this ratio. Collectively, these findings provide preliminary indications that kefir water may hold potential as a dietary approach to modulate gut microbial changes associated with ageing. However, confirmation through studies with larger sample sizes and broader analytical coverage is necessary to substantiate these initial observations. Full article