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18 pages, 613 KB  
Article
Comparison of Shoulder and Elbow Biomechanical Characteristics in Left- and Right-Handed Youth Baseball Players
by Hitoshi Shitara, Tsuyoshi Tajika, Tsuyoshi Ichinose, Tsuyoshi Sasaki, Noritaka Hamano, Masataka Kamiyama, Ryosuke Miyamoto, Kurumi Nakase, Fukuhisa Ino, Takuma Kachi, Yuhei Hatori, Koichiro Yanai, Atsushi Yamamoto, Kenji Takagishi and Hirotaka Chikuda
J. Clin. Med. 2025, 14(24), 8638; https://doi.org/10.3390/jcm14248638 - 5 Dec 2025
Viewed by 340
Abstract
Background/Objectives: This study investigated biomechanical differences between right-handed (RHPs) and left-handed (LHPs) youth baseball players by analyzing shoulder and elbow range of motion (ROM), muscle strength, and humeral torsion. Side-to-side asymmetries were also examined to identify potential handedness-related adaptations. Methods: This cross-sectional study [...] Read more.
Background/Objectives: This study investigated biomechanical differences between right-handed (RHPs) and left-handed (LHPs) youth baseball players by analyzing shoulder and elbow range of motion (ROM), muscle strength, and humeral torsion. Side-to-side asymmetries were also examined to identify potential handedness-related adaptations. Methods: This cross-sectional study included 2008 youth baseball players (1829 RHPs and 179 LHPs) aged 9–13 years; female players were excluded because of their small number, and only male participants were analyzed. Shoulder and elbow ROM, muscle strength, and humeral torsion were evaluated, with humeral torsion data collected from 1024 measurements (946 RHPs, 78 LHPs). Group differences were analyzed using the Mann–Whitney U and Wilcoxon Signed-Rank tests. Logistic regression analysis identified independent factors associated with being an LHP, while Pearson correlation analyses explored the relationships between humeral torsion and external/internal rotation. Results: LHPs exhibited significantly larger nondominant shoulder external rotation (p < 0.001), dominant internal rotation (p = 0.003), dominant shoulder horizontal adduction (p = 0.007), dominant elbow flexion (p = 0.006), and side-to-side prone internal rotation strength ratio (p < 0.001). LHPs also showed smaller dominant shoulder external rotation (p = 0.012), nondominant shoulder internal rotation (p = 0.001), nondominant horizontal adduction (p = 0.037), dominant prone external rotation strength (p = 0.002), and humeral torsion (p = 0.031). Humeral torsion differences correlated with external rotation in LHPs (r = 0.236) and internal rotation in RHPs (r = −0.153). Predictors of left-handedness included lower dominant shoulder external rotation (OR = 0.937) and higher dominant elbow flexion (OR = 1.410). Conclusions: This study provides novel insights into the normal functional characteristics of LHPs, an area that has been relatively underexplored. These findings serve as a basis for future studies on risk assessment, injury prevention, and performance optimization in youth baseball players. Full article
(This article belongs to the Section Sports Medicine)
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16 pages, 311 KB  
Article
Laser Hemorrhoidoplasty: Postoperative Outcomes and Predictive Factors for Pain, Bleeding, and Recovery
by Laurențiu Augustus Barbu, Nicolae-Dragoș Mărgăritescu, Liliana Cercelaru, Tiberiu Stefăniță Țenea Cojan, Mădălina Costinela Stănică, Irina Enăchescu, Ana-Maria Țenea Cojan, Valentina Căluianu, Gabriel Florin Răzvan Mogoș and Liviu Vasile
Life 2025, 15(11), 1777; https://doi.org/10.3390/life15111777 - 19 Nov 2025
Viewed by 1091
Abstract
Background: Laser hemorrhoidoplasty (LHP) is a minimally invasive alternative to excisional hemorrhoidectomy, with promising short-term outcomes. However, predictors of postoperative pain, bleeding, and recovery remain insufficiently characterized. Methods: We conducted a prospective study including 140 patients with Goligher grade I–IV hemorrhoidal disease (January [...] Read more.
Background: Laser hemorrhoidoplasty (LHP) is a minimally invasive alternative to excisional hemorrhoidectomy, with promising short-term outcomes. However, predictors of postoperative pain, bleeding, and recovery remain insufficiently characterized. Methods: We conducted a prospective study including 140 patients with Goligher grade I–IV hemorrhoidal disease (January 2020–December 2024) at Independența Vita Plus Hospital, Craiova. All patients received preoperative diosmin and topical ointments. Procedures were performed under spinal anesthesia using a standardized 1470 nm diode laser technique. Outcomes included postoperative pain (VAS), bleeding, early and late complications, recovery time, HDSS change, and quality of life assessed with a simple 0–10 numerical scale used in routine clinical practice (not a validated QoL instrument). Results: Mean operative time was 17.9 ± 4.8 min, with minimal blood loss. Postoperative bleeding occurred in 28.6% and was mild. Early complications increased with disease stage: 10% (II), 53% (III), 68% (IV) (p < 0.001). VAS pain decreased from 2.1 on day 1 to 0.3 on day 7 (p < 0.0001). Median recovery time was 3 days, longer in advanced stages. HDSS improved from 10.3 ± 2.5 preoperatively to 1.7 ± 1.1 at 3 months (p < 0.0001). QoL numerical scores also improved significantly at 3 months. Goligher grade independently predicted late bleeding (OR 70.2), high pain (OR 4.9), and prolonged recovery (OR 8.6). No recurrences were observed at 12 months. Conclusions: LHP provides low postoperative pain, minimal bleeding, rapid recovery, and significant symptom and QoL improvement. Disease severity strongly predicts outcomes and should guide perioperative planning. Full article
17 pages, 2038 KB  
Article
Numerical Study on the Vapor–Liquid Interface in the Evaporator of Loop Heat Pipes with Multiscale Wicks Using Pore Network Simulation
by Seunghyeok Jeon, Seo Yeon Kang, Sung Jun Park, Hee Soo Myeong and Seok Pil Jang
Energies 2025, 18(17), 4526; https://doi.org/10.3390/en18174526 - 26 Aug 2025
Cited by 1 | Viewed by 898
Abstract
This study numerically and experimentally investigated the maximum heat transfer rate of the evaporator in loop heat pipes (LHPs) using a pore network simulation that considers the vapor–liquid interface within the evaporator wick under high heat flux conditions. The numerical model was validated [...] Read more.
This study numerically and experimentally investigated the maximum heat transfer rate of the evaporator in loop heat pipes (LHPs) using a pore network simulation that considers the vapor–liquid interface within the evaporator wick under high heat flux conditions. The numerical model was validated with previous results. Based on the validated model, the boundary conditions were modified to consider high heat flux conditions. Also, a porous medium approach was applied to predict the working fluid flow in multiscale wicks, which were fabricated by sintering micro-sized SAC305 particles onto conventional screen mesh wicks. The effective pore radius and permeability of multiscale wicks were experimentally measured using the rate-of-rise method. Using the modified numerical model and experimental results, a parametric study was conducted on sintered weight fraction (SWF), fin ratio, and wick thickness to evaluate their effects on the maximum heat transfer rate of the LHP evaporator. As a result, the maximum heat transfer rate increased with higher SWF and thicker wicks due to improved capillary performance and greater vapor growth space, while a higher fin ratio reduced the maximum heat transfer rate by decreasing the vapor groove area. Under optimal conditions, a maximum heat flux of 800 W/cm2 was achieved. Full article
(This article belongs to the Section J: Thermal Management)
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27 pages, 5016 KB  
Article
Comparison Study of Novel Flat Evaporator Loop Heat Pipes with Different Types of Condensation Pipeline
by Kangning Xiong, Yang Liu, Zhuoyu Li and Qingsong Pan
Energies 2025, 18(16), 4247; https://doi.org/10.3390/en18164247 - 9 Aug 2025
Viewed by 1218
Abstract
Chip-level cooling has become a thermal bottleneck in next-generation data centers. Although previous studies have optimized evaporator wick structures, they are limited to a single condensation path and ignore the combined effects of the loop heat pipe (LHP) orientation on the capillary wick [...] Read more.
Chip-level cooling has become a thermal bottleneck in next-generation data centers. Although previous studies have optimized evaporator wick structures, they are limited to a single condensation path and ignore the combined effects of the loop heat pipe (LHP) orientation on the capillary wick (CW) replenishment and reflux subcooling. To bridge this gap, this study successfully designed an innovative flat-plate evaporator water-cooled LHP with a parallel condensation pipeline. Experiments were conducted with a 20 °C coolant and at a 4 L/min flow rate across nine orientations. The heat transfer characteristics of LHPs with parallel and series condensation pipelines were compared. The analysis focused on the relationship between the working fluid (WF) replenishment of the CW and the WF reflux temperature in the compensating chamber (CC). The experimental results demonstrated that the parallel condensation LHP could sustainably dissipate 750 W without thermal runaway. At this power, the minimum junction temperature of 82.34 °C was measured at orientation 2 (+60°). For low power and at the nine orientations, the series LHP generally had lower temperatures. However, when the power exceeded 600 W, the parallel LHP showed lower temperatures at orientations 1 (+90°), 2 (+60°), and 3 (+30°). At orientation 9, the parallel LHP had lower temperatures when the power surpassed 200 W. Theoretical analysis indicated that the orientation changes affected the heat transfer via the WF reflux temperature, reflux resistance, and CW replenishment rate. Furthermore, the LHP system we developed in this study is capable of fully satisfying the cooling requirements of data center server chips. Full article
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17 pages, 2387 KB  
Article
Application of Lactobacillus helveticus KLDS 1.1105 Postbiotics for Resisting Pathogenic Bacteria Infection in the Intestine
by Peng Du, Jiaying Liu, Chengwen Hu, Jianing Zhang, Miao Li, Yu Xin, Libo Liu, Aili Li and Chun Li
Foods 2025, 14(15), 2659; https://doi.org/10.3390/foods14152659 - 29 Jul 2025
Viewed by 1029
Abstract
Postbiotics, defined as metabolites produced by probiotics, encompass both bacterial cells and their metabolic byproducts, and offer significant health benefits to the host. However, there are relatively few reports on their effects on intestinal microbiota. In this study, we investigated the components, total [...] Read more.
Postbiotics, defined as metabolites produced by probiotics, encompass both bacterial cells and their metabolic byproducts, and offer significant health benefits to the host. However, there are relatively few reports on their effects on intestinal microbiota. In this study, we investigated the components, total antioxidant capacity of Lactobacillus helveticus postbiotics (LHPs) and their impact on intestinal flora using the Simulator for Human Intestinal Microecology Simulation (SHIME). The results indicate that the primary components of postbiotics include polysaccharides, proteins, and organic acids. Furthermore, LHPs have a strong ability to inhibit the growth of harmful bacteria while promoting the growth of probiotics. Additionally, LHPs significantly increased the total antioxidant capacity in the intestine and regulated the balance of intestinal microbiota. Notably, there was also a significant increase in the content of short-chain fatty acids (SCFAs) in the intestine. Overall, LHPs have the potential to aid in the prevention and treatment of diseases by enhancing gut microbiology. Full article
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11 pages, 2726 KB  
Article
Analysis of Key Material Parameters of Evaporator Wicks and Working Fluids for a Loop Heat Pipe Operating in the Temperature Range of 500–700 K
by Paweł Szymański, Piotr Radomski, Jae-Ho Jeon and Dariusz Mikielewicz
Materials 2025, 18(12), 2798; https://doi.org/10.3390/ma18122798 - 13 Jun 2025
Viewed by 797
Abstract
This study presents a preliminary evaluation of candidate wick material and working fluid for a flat-loop heat pipe (F-LHP) designed to operate within the temperature range of 500–700 K. The selection process considered key thermal and physical parameters, including thermal conductivity, chemical compatibility [...] Read more.
This study presents a preliminary evaluation of candidate wick material and working fluid for a flat-loop heat pipe (F-LHP) designed to operate within the temperature range of 500–700 K. The selection process considered key thermal and physical parameters, including thermal conductivity, chemical compatibility between wick and fluid, capillary pressure generation, pressure drop across the wick structure, and structural integrity at elevated temperatures. A range of metallic and ceramic wick materials, along with suitable high-temperature working fluids, were reviewed and compared based on performance metrics and practical availability. Special attention was given to oxidation and corrosion resistance, capillary performance, and thermal stability under elevated-temperature conditions. Nine different porous wicks with distinct materials and microstructures—differing in pore size, porosity, and permeability—were analyzed in combination with seven different working fluids. The analysis focused on determining which combinations generated the highest capillary pressure and which exhibited the lowest flow resistance due to external flow, thereby enhancing the LHP’s performance. Based on these results, the study identifies the most effective wick–fluid pairings for F-LHP applications, offering an optimal balance of thermal performance and long-term reliability. These findings provide a foundation for further experimental validation and the development of prototypes. Full article
(This article belongs to the Section Materials Physics)
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15 pages, 2466 KB  
Article
Gram-Scale Synthesis and Optical Properties of Self-Trapped-Exciton-Emitting Two-Dimensional Tin Halide Perovskites
by Yifeng Xing, Jialin Yin, Yifei Qiao, Jie Zhao, Haiyang He, Danyang Zhao, Wanlu Zhang, Shiliang Mei and Ruiqian Guo
Nanomaterials 2025, 15(11), 818; https://doi.org/10.3390/nano15110818 - 28 May 2025
Viewed by 855
Abstract
Lead halide perovskites (LHPs) have superior luminescent properties, but their toxicity hinders their commercialization, arousing interests in tin halide perovskites as environmentally friendly substitutes for LHPs. Herein, we synthesized a series of two-dimensional tin halide perovskite ODASnBr4-xIx (ODA denotes 1,8-octanediammonium, [...] Read more.
Lead halide perovskites (LHPs) have superior luminescent properties, but their toxicity hinders their commercialization, arousing interests in tin halide perovskites as environmentally friendly substitutes for LHPs. Herein, we synthesized a series of two-dimensional tin halide perovskite ODASnBr4-xIx (ODA denotes 1,8-octanediammonium, X = 0, 1, 2, 3, 4) microcrystals via an aqueous-phase method. The differences between ODASnI4 and ODASnBr4 in luminescent properties and morphological characteristics were systematically discussed for the first time and attributed to light-driven ligand-to-metal charge transfer. The prepared ODASnBr4 has a PL peak at 567 nm and a PL QY of 99%, and the white light-emitting diodes fabricated with ODASnBr4 and commercial blue phosphors realized a luminous efficacy of up to 96.27 lm/W, which demonstrated the remarkable potential of ODASnBr4 microcrystals for high-efficiency white light-emitting diode applications. Full article
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13 pages, 1143 KB  
Article
Activation of Perovskite Nanocrystals for Volumetric Displays Using Near-Infrared Photon Upconversion by Triplet Fusion
by Yu Hu, Guiwen Luo, Pengfei Niu, Ling Zhang, Tianjun Yu, Jinping Chen, Yi Li and Yi Zeng
Molecules 2025, 30(11), 2273; https://doi.org/10.3390/molecules30112273 - 22 May 2025
Cited by 1 | Viewed by 1187
Abstract
Coupling organic light-harvesting materials with lead halide perovskite quantum dots (LHP QDs) is an attractive approach that could provide great potential in optoelectronic applications owing to the diversity of organic materials available and the intriguing optical and electronic properties of LHP QDs. Here, [...] Read more.
Coupling organic light-harvesting materials with lead halide perovskite quantum dots (LHP QDs) is an attractive approach that could provide great potential in optoelectronic applications owing to the diversity of organic materials available and the intriguing optical and electronic properties of LHP QDs. Here, we demonstrate energy collection by CsPbI3 QDs from a near-infrared (NIR) light-harvesting upconversion system. The upconversion system consists of Pd-tetrakis-5,10,15,20-(p-methoxycarbonylphenyl)-tetraanthraporphyrin (PdTAP) as the sensitizer to harvest NIR photons and rubrene as the annihilator to generate upconverted photons via triplet fusion. Steady-state and time-resolved photoluminescence spectra reveal that CsPbI3 QDs are energized via radiative energy transfer from the singlet excited rubrene with photophysics fidelity of respective components. In addition, a volumetric display demo incorporating CsPbI3 QDs as light emitters employing triplet fusion upconversion was developed, showing bright luminescent images from CsPbI3 QDs. These results present the feasibility of integrating organic light-harvesting systems and perovskite QDs, enabling diverse light harvesting and activation of perovskite materials for optoelectronic applications. Full article
(This article belongs to the Special Issue Photochemistry in Asia)
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18 pages, 7914 KB  
Article
Direct Comparison of Infrared Channel Measurements by Two ABIs to Monitor Their Calibration Stability
by Fangfang Yu, Xiangqian Wu, Hyelim Yoo, Hui Xu and Haifeng Qian
Remote Sens. 2025, 17(10), 1656; https://doi.org/10.3390/rs17101656 - 8 May 2025
Viewed by 782
Abstract
This paper introduces a method of monitoring infrared channel calibration stability through direct comparison of calibrated radiances by two Advanced Baseline Imager (ABI) on two geostationary (GEO) platforms. This GEO-GEO comparison is based on radiances in the overlapping area observed by the two [...] Read more.
This paper introduces a method of monitoring infrared channel calibration stability through direct comparison of calibrated radiances by two Advanced Baseline Imager (ABI) on two geostationary (GEO) platforms. This GEO-GEO comparison is based on radiances in the overlapping area observed by the two ABIs, pixel by pixel, at approximately the same time, location, spectrum, and viewing zenith angle. It was initially developed for GOES-17 and subsequent GOES missions to validate the ABI’s calibration around its local midnight—a subject of particular interest for instruments on three-axis stabilized geostationary satellites. With the cryocooler anomaly of the GOES-17 ABI, however, the GEO-GEO comparison became an indispensable tool to characterize GOES-17 ABI infrared (IR) channel calibration with high frequency, low uncertainty, and in near real time, providing critical feedback to root cause investigation and mitigation options. Later, the GEO-GEO comparison was applied to the GOES-18 ABI as originally intended and was proved successful. It confirms that, with few exceptions, radiometric calibration for all ABIs is stable to within 0.1 K when the radiance fluctuation is converted to the brightness temperature at 300 K. Full article
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27 pages, 13789 KB  
Review
Long-Term Analysis of Hydropower’s Pivotal Role in Sustainable Future of Greece
by John K. Kaldellis
Energies 2025, 18(9), 2214; https://doi.org/10.3390/en18092214 - 27 Apr 2025
Cited by 1 | Viewed by 1670
Abstract
Hydropower, a proven renewable electricity generation technology, has satisfied approximately 16% of the global annual electricity consumption up to the present day. In Greece, hydropower applications throughout the last thirty years have covered almost 6–10% of the mainland’s annual electricity demand. The present [...] Read more.
Hydropower, a proven renewable electricity generation technology, has satisfied approximately 16% of the global annual electricity consumption up to the present day. In Greece, hydropower applications throughout the last thirty years have covered almost 6–10% of the mainland’s annual electricity demand. The present work examines the long-term performance and the current status of hydropower applications in Greece as well as their potential contribution to accomplishing the national energy targets set in compliance with the European Directives. A dedicated visualization of large hydropower (LHP) plants’ main characteristics is also performed. Moreover, a critical evaluation of the existing LHP plants’ energy yield-based time evolution is carried out, attempting to provide insights into any fundamental trends and similarities. The analysis reveals that the majority of Greek LHP plants are primarily used to meet the corresponding mainland’s peak load demand. To this end, acknowledging the power balancing service capacity of pumped hydro storage stations, the prospects and the challenges for the specific energy storage technology’s deployment are also emphasized. Full article
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20 pages, 6080 KB  
Article
Comprehensive Evaluation of Cultivated Land Quality in Black Soil of Northeast China: Emphasizing Functional Diversity and Risk Management
by Huaizhi Tang, Yuanyuan Zhang, Qi Liu, Mengyu Guo, Jiacheng Niu, Qiuyue Xia, Mengyin Liang, Yunjia Liu, Yuanfang Huang and Yamin Du
Appl. Sci. 2025, 15(7), 3753; https://doi.org/10.3390/app15073753 - 29 Mar 2025
Cited by 3 | Viewed by 1786
Abstract
The cultivated land in the black soil of Northeast China (BSNC), due to long-term high-input and high-output utilization, is facing a series of challenges such as soil erosion, compaction, and nutrient loss. However, the existing cultivated land quality evaluation (CLQE) lacks regional specificity, [...] Read more.
The cultivated land in the black soil of Northeast China (BSNC), due to long-term high-input and high-output utilization, is facing a series of challenges such as soil erosion, compaction, and nutrient loss. However, the existing cultivated land quality evaluation (CLQE) lacks regional specificity, making it difficult to accurately reflect the cultivated land quality (CLQ) characteristics across different areas. Therefore, this study proposes a comprehensive evaluation framework that integrates both cultivated land functionality and degradation risk, establishing an assessment system consisting of 18 indicators to comprehensively evaluate the CLQ in the BSNC from multiple perspectives. The results indicate that the CLQ in the BSNC exhibits a declining trend from north to south, with second- and third-grade land dominating, accounting for 75.68% of the total cultivated land area. The overall cultivated land functionality increases from west to east, with the Liaohe Plain Region (LHP) performing the best. Low-risk cultivated land is primarily concentrated in the Songnen Plain Region (SNP) and the Western Sandy Region (WS), covering 38.55% of the total cultivated land area. Additionally, this study finds a trade-off between the primary productivity function and the resource utilization efficiency function across different regions, while a synergistic relationship is observed between resource utilization efficiency and soil nutrient maintenance functions. This research emphasizes the necessity of balancing productivity and ecological protection to achieve the sustainable and efficient use of the BSNC. Full article
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24 pages, 4110 KB  
Article
A Comparative Life Cycle Analysis of an Active and a Passive Battery Thermal Management System for an Electric Vehicle: A Cold Plate and a Loop Heat Pipe
by Michele Monticelli, Antonella Accardo, Marco Bernagozzi and Ezio Spessa
World Electr. Veh. J. 2025, 16(2), 100; https://doi.org/10.3390/wevj16020100 - 12 Feb 2025
Cited by 3 | Viewed by 3265
Abstract
This study extends beyond conventional Battery Thermal Management System (BTMS) research by conducting a Life Cycle Analysis comparing the environmental impacts of two technologies: a traditional active cold plate system and an innovative passive Loop Heat Pipe (LHP) system. While active cold plate [...] Read more.
This study extends beyond conventional Battery Thermal Management System (BTMS) research by conducting a Life Cycle Analysis comparing the environmental impacts of two technologies: a traditional active cold plate system and an innovative passive Loop Heat Pipe (LHP) system. While active cold plate BTMS requires continuous energy input during operation and charging, leading to significant energy consumption and emissions, the passive LHP BTMS operates without external power or moving parts, substantially reducing the climate change impact. This analysis considered two materials for LHP construction: copper and stainless steel. The results demonstrated that the LHP design achieved a 9.9 kg reduction in overall BTMS mass compared to the cold plate system. The implementation of stainless steel effectively addressed the high resource consumption associated with copper while reducing environmental impact by over 50% across most impact categories, compared to the cold plate BTMS. The passive operation of the LHP system leads to substantially lower energy usage and emissions during the use phase compared to the active cold plate. These findings highlight the potential of passive LHP technology to enhance the environmental sustainability of Battery Thermal Management Systems while maintaining effective thermal performance. Full article
(This article belongs to the Special Issue Heat Pipes in Thermal Management Systems for Electric Vehicles)
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25 pages, 7109 KB  
Review
Research Progress on Quantum Dot-Embedded Polymer Films and Plates for LCD Backlight Display
by Bin Xu, Jiankang Zhou, Chengran Zhang, Yunfu Chang and Zhengtao Deng
Polymers 2025, 17(2), 233; https://doi.org/10.3390/polym17020233 - 17 Jan 2025
Cited by 7 | Viewed by 4824
Abstract
Abstract: Quantum dot–polymer composites have the advantages of high luminescent quantum yield (PLQY), narrow emission half-peak full width (FWHM), and tunable emission spectra, and have broad application prospects in display and lighting fields. Research on quantum dots embedded in polymer films and plates [...] Read more.
Abstract: Quantum dot–polymer composites have the advantages of high luminescent quantum yield (PLQY), narrow emission half-peak full width (FWHM), and tunable emission spectra, and have broad application prospects in display and lighting fields. Research on quantum dots embedded in polymer films and plates has made great progress in both synthesis technology and optical properties. However, due to the shortcomings of quantum dots, such as cadmium selenide (CdSe), indium phosphide (InP), lead halide perovskite (LHP), poor water, oxygen, and light stability, and incapacity for large-scale synthesis, their practical application is still restricted. Various polymers, such as methyl methacrylate (PMMA), polyethylene terephthalate (PET), polystyrene (PS), polyvinylidene fluoride (PVDF), polypropylene (PP), etc., are widely used in packaging quantum dot materials because of their high plasticity, simple curing, high chemical stability, and good compatibility with quantum dot materials. This paper focuses on the application and development of quantum dot–polymer materials in the field of backlight displays, summarizes and expounds the synthesis strategies, advantages, and disadvantages of different quantum dot–polymer materials, provides inspiration for the optimization of quantum dot–polymer materials, and promotes their application in the field of wide-color-gamut backlight display. Full article
(This article belongs to the Special Issue Polymers/Their Hybrid Materials for Optoelectronic Applications)
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18 pages, 3954 KB  
Article
Investigation of a Gas-Pump-Driven Loop Heat Pipe
by Yangyiming Rong, Weitao Su, Shuai Wang, Bowen Du, Zujun Mao and Shaozhi Zhang
Energies 2024, 17(21), 5283; https://doi.org/10.3390/en17215283 - 24 Oct 2024
Cited by 1 | Viewed by 1109
Abstract
A loop heat pipe (LHP) is an efficient method of conserving energy in data center cooling applications. In scenarios where the installation is constrained by height or distance limitations, pump driving is needed. This paper examines the performance changes induced by a gas [...] Read more.
A loop heat pipe (LHP) is an efficient method of conserving energy in data center cooling applications. In scenarios where the installation is constrained by height or distance limitations, pump driving is needed. This paper examines the performance changes induced by a gas pump both experimentally and theoretically. An adjustable, oil-free linear compressor is utilized as a gas pump. The evaporator is a finned-tube heat exchanger and the condenser is a water-cooled plate heat exchanger. When the filling ratio of the working fluid is insufficient, employing a gas pump can enhance the heat transfer performance. However, when the filling ratio of the working fluid is sufficient, while the gas pump can increase the flowrate of the working fluid, the heat transfer rate (HTR) does not change significantly. In fact, it may reduce the energy efficiency ratio of the heat pipe. Infrared thermography has proven to be an efficient tool for estimating the area ratio of different zones within the evaporator, which is crucial for the output regulation of the compressor. The area ratio of the two-phase zone is nearly linear to the HTR. Through the establishment of a physical model of a gas-pump-driven loop heat pipe (GPLHP), the impacts of the LHP size and gas pump operation on the heat transfer performance are analyzed. It is found that the gas pump can extend the application range of the LHP, although it has a minimal impact on the maximum HTR. How to select a gas pump for an LHP is discussed. Full article
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15 pages, 3934 KB  
Article
A Tumor Homing Peptide-Linked Arsenic Compound Inhibits Pancreatic Cancer Growth and Enhances the Inhibitory Effect of Gemcitabine
by Hong He, Chelsea Dumesny, Judith A. Carrall, Carolyn T. Dillon, Katja I. de Roo, Mal Eutick, Li Dong, Graham S. Baldwin and Mehrdad Nikfarjam
Int. J. Mol. Sci. 2024, 25(21), 11366; https://doi.org/10.3390/ijms252111366 - 22 Oct 2024
Cited by 1 | Viewed by 3939
Abstract
Arsenic trioxide (ATO) has been shown to inhibit pancreatic cancer (PC) cell growth in vitro and to promote the inhibitory effects of gemcitabine (Gem) on PC in vivo. However, the high toxicity of ATO associated with the required high doses and indiscriminate [...] Read more.
Arsenic trioxide (ATO) has been shown to inhibit pancreatic cancer (PC) cell growth in vitro and to promote the inhibitory effects of gemcitabine (Gem) on PC in vivo. However, the high toxicity of ATO associated with the required high doses and indiscriminate targeting has limited its clinical application. This study aimed to determine whether coupling arsenic to a tumor homing peptide would increase the inhibitory potency against PC cells. The effects of this peptide-linked arsenic compound (PhAs-LHP), the analogous non-targeting arsenic compound (phenylarsine oxide, PAO), and marketed ATO on PC growth were tested in vitro and in a mouse model. The data demonstrated that PhAs-LHP inhibited PC cell growth in vitro more potently, with IC50 values 10 times lower than ATO. Like ATO, PhAs-LHP induced cell death and cell cycle arrest. This cytotoxic effect of PhAs-LHP was mediated via a macropinocytosis-linked uptake pathway as amiloride (a macropinocytosis inhibitor) reduced the inhibitory effect of PhAs-LHP. More importantly, PhAs-LHP inhibited PC growth in mice and enhanced the inhibitory effect of Gem on PC growth at 2 times lower molar concentration than PAO. These results indicate that PhAs-LHP inhibited PC more potently than ATO/PAO and suggest a potential clinical use for the combination of Gem with the peptide-linked arsenic compound for the treatment of pancreatic cancer. Full article
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