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Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon

  • Rickard Lundberg,
  • Krister Melén,
  • Veera Westenius,
  • Miao Jiang,
  • Pamela Österlund,
  • Hira Khan,
  • Olli Vapalahti,
  • Ilkka Julkunen and
  • Laura Kakkola
Viruses2019, 11(11), 1024;https://doi.org/10.3390/v11111024

4 November 2019

The Zika virus (ZIKV) is a member of the Flaviviridae family and an important human pathogen. Most pathogenic viruses encode proteins that interfere with the activation of host innate immune responses. Like other flaviviruses, ZIKV interferes with th...

(This article belongs to the Section Animal Viruses)
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