2 Results Found

Advanced Search

Select all

Results per page

Select all

Article

3 Citations

2,771 Views

21 Pages

A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso

Jules Cretin,
Mathieu Adjemout,
Christelle Dieppois,
Frederic Gallardo and ,
Magali Torres,
Zachary Merard,
Serge Aimé Sawadogo,
Christophe Picard,
Pascal Rihet and
Pascale Paul
+ 5 authors+ 0 author

Int. J. Mol. Sci.2023, 24(21), 15711;https://doi.org/10.3390/ijms242115711

28 October 2023

Antibodies play a crucial role in activating protective immunity against malaria by interacting with Fc-gamma receptors (FcγRs). Genetic variations in genes encoding FcγRs can affect immune cell responses to the parasite. In this study, o...

(This article belongs to the Section Molecular Immunology)

Full Article

Article

4 Citations

3,326 Views

14 Pages

Mendelian Randomization Reveals Potential Causal Relationships Between DNA Damage Repair-Related Genes and Inflammatory Bowel Disease

Zhihao Qi,
Quan Li,
Shuhua Yang,
Chun Fu and
Burong Hu

Biomedicines2025, 13(1), 231;https://doi.org/10.3390/biomedicines13010231

19 January 2025

DNA damage repair (DDR) plays a key role in maintaining genomic stability and developing inflammatory bowel disease (IBD). However, no report about the causal association between DDR and IBD exists. Whether DDR-related genes are the precise causal as...

(This article belongs to the Section Molecular Genetics and Genetic Diseases)

Full Article