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7 Results Found

  • Article
  • Open Access
1 Citations
1,004 Views
8 Pages

Urinary 5-HIAA as a Potential Diagnostic Marker in Acute Appendicitis: A Preliminary Report of Its Promising Role in Early Detection

  • Murat Demir,
  • Alper Gumus,
  • Huseyin Kilavuz,
  • Feyyaz Gungor,
  • Sibel Yaman,
  • Baki Ekci and
  • Idris Kurtulus

11 June 2025

Background: Acute appendicitis (AA) is a common surgical emergency worldwide. Over the past few decades, diagnostic imaging has become a cornerstone in the identification of acute appendicitis, significantly contributing to the reduction in unnecessa...

  • Feature Paper
  • Article
  • Open Access
7 Citations
4,908 Views
11 Pages

Quality Outcomes in Appendicitis Care: Identifying Opportunities to Improve Care

  • Syed Mohammad Umar Kabir,
  • Magda Bucholc,
  • Carol-Ann Walker,
  • Opeyemi O. Sogaolu,
  • Saqib Zeeshan and
  • Michael Sugrue

18 December 2020

Introduction: Appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention, but the variability of diagnosis and management continue to challenge the surgeons. Aim: This study assessed patients undergoing appe...

  • Article
  • Open Access
19 Citations
4,746 Views
24 Pages

Appendicitis Diagnosis: Ensemble Machine Learning and Explainable Artificial Intelligence-Based Comprehensive Approach

  • Mohammed Gollapalli,
  • Atta Rahman,
  • Sheriff A. Kudos,
  • Mohammed S. Foula,
  • Abdullah Mahmoud Alkhalifa,
  • Hassan Mohammed Albisher,
  • Mohammed Taha Al-Hariri and
  • Nazeeruddin Mohammad

Appendicitis is a condition wherein the appendix becomes inflamed, and it can be difficult to diagnose accurately. The type of appendicitis can also be hard to determine, leading to misdiagnosis and difficulty in managing the condition. To avoid comp...

  • Article
  • Open Access
13 Citations
4,542 Views
12 Pages

Background: Appendectomy is still the standard treatment for acute appendicitis in the majority of centers. Despite all available diagnostic tools, the rates of negative appendectomies are still relatively high. This study aimed to determine negative...

  • Article
  • Open Access
1,731 Views
9 Pages

Poor Compliance to Clinical Guidelines in the Diagnosis of Acute Appendicitis: Insights from a National Survey

  • Nir Messer,
  • Avi Benov,
  • Adi Rov,
  • Tali Bar-On,
  • Oran Zlotnik,
  • Jacob Chen and
  • Haim Paran

13 May 2024

Background: Many scoring systems, algorithms, and guidelines have been developed to aid in the evaluation and diagnosis of acute appendicitis (AA). Many of these algorithms advocate against the routine use of radiological investigations when there is...

  • Article
  • Open Access
1 Citations
2,181 Views
11 Pages

Diagnostic Accuracy of a Machine Learning-Derived Appendicitis Score in Children: A Multicenter Validation Study

  • Emrah Aydın,
  • Taha Eren Sarnıç,
  • İnan Utku Türkmen,
  • Narmina Khanmammadova,
  • Ufuk Ateş,
  • Mustafa Onur Öztan,
  • Tamer Sekmenli,
  • Necip Fazıl Aras,
  • Tülin Öztaş and
  • Süleyman Cüneyt Karakuş
  • + 17 authors

16 July 2025

Background: Accurate diagnosis of acute appendicitis in children remains challenging due to variable presentations and limitations of existing clinical scoring systems. While machine learning (ML) offers a promising approach to enhance diagnostic pre...

  • Article
  • Open Access
3 Citations
3,230 Views
14 Pages

Suspected Simple Appendicitis in Children: Should We Use a Nonoperative, Antibiotic-Free Approach? An Observational Study

  • Patricia Reis Wolfertstetter,
  • John Blanford Ebert,
  • Judith Barop,
  • Markus Denzinger,
  • Michael Kertai,
  • Hans J. Schlitt and
  • Christian Knorr

13 March 2024

Background: Simple appendicitis may be self-limiting or require antibiotic treatment or appendectomy. The aim of this study was to assess the feasibility and safety of a nonoperative, antibiotic-free approach for suspected simple appendicitis in chil...