Vaccines | Highly Cited Papers in the First Half of 2025
29 January 2026
1. “Beyond the Pandemic Era: Recent Advances and Efficacy of SARS-CoV-2 Vaccines Against Emerging Variants of Concern”
by Ankita Saha, Sounak Ghosh Roy, Richa Dwivedi, Prajna Tripathi, Kamal Kumar, Shashank Manohar Nambiar and Rajiv Pathak
Vaccines 2025, 13(4), 424; https://doi.org/10.3390/vaccines13040424
Available online: https://www.mdpi.com/2076-393X/13/4/424
2. “Advances and Challenges in Aeromonas hydrophila Vaccine Development: Immunological Insights and Future Perspectives”
by Kavi R. Miryala and Banikalyan Swain
Vaccines 2025, 13(2), 202; https://doi.org/10.3390/vaccines13020202
Available online: https://www.mdpi.com/2076-393X/13/2/202
3. “Molecular Farming for Immunization: Current Advances and Future Prospects in Plant-Produced Vaccines”
by Dang-Khoa Vo and Kieu The Loan Trinh
Vaccines 2025, 13(2), 191; https://doi.org/10.3390/vaccines13020191
Available online: https://www.mdpi.com/2076-393X/13/2/191
4. “Revolutionizing Nanovaccines: A New Era of Immunization”
by Mohammed Saleh, Ahmed El-Moghazy, Adel H. Elgohary, WesamEldin I. A. Saber and Yosra A. Helmy
Vaccines 2025, 13(2), 126; https://doi.org/10.3390/vaccines13020126
Available online: https://www.mdpi.com/2076-393X/13/2/126
5. “Pediatric Vaccine Hesitancy in the United States—The Growing Problem and Strategies for Management Including Motivational Interviewing”
by Ashlesha Kaushik, Julia Fomicheva, Nathan Boonstra, Elizabeth Faber, Sandeep Gupta and Helen Kest
Vaccines 2025, 13(2), 115; https://doi.org/10.3390/vaccines13020115
Available online: https://www.mdpi.com/2076-393X/13/2/115
6. “Progress and Challenges in HIV-1 Vaccine Research: A Comprehensive Overview”
by Alex C. Boomgarden and Chitra Upadhyay
Vaccines 2025, 13(2), 148; https://doi.org/10.3390/vaccines13020148
Available online: https://www.mdpi.com/2076-393X/13/2/148
7. “Pertussis in Early Infancy: Diagnostic Challenges, Disease Burden, and Public Health Implications Amidst the 2024 Resurgence, with Emphasis on Maternal Vaccination Strategies”
by Konstantina Leontari, Alexandra Lianou, Andreas G. Tsantes, Filippos Filippatos, Zoi Iliodromiti, Theodora Boutsikou, Styliani Paliatsou, Anastasios E. Chaldoupis, Petros Ioannou, Alexandra Mpakosi et al.
Vaccines 2025, 13(3), 276; https://doi.org/10.3390/vaccines13030276
Available online: https://www.mdpi.com/2076-393X/13/3/276
8. “No Increased Risk of Autoimmune Diseases Following HPV Vaccination: A Systematic Review and Meta-Analysis”
by Filippo Alberto Ferrari, Enrico Ciminello, Marcello Ceccaroni, Matteo Pavone, Violante Di Donato, Giorgia Perniola, Pierluigi Benedetti Panici, Ludovico Muzii, Andrea Giannini, Giuseppe Vizzielli et al.
Vaccines 2025, 13(4), 391; https://doi.org/10.3390/vaccines13040391
Available online: https://www.mdpi.com/2076-393X/13/4/391
9. “The New Era of Pneumococcal Vaccination in Adults: What Is Next?”
by Lale Ozisik
Vaccines 2025, 13(5), 498; https://doi.org/10.3390/vaccines13050498
Available online: https://www.mdpi.com/2076-393X/13/5/498
10. “Advancing Breast Cancer Treatment: The Role of Immunotherapy and Cancer Vaccines in Overcoming Therapeutic Challenges”
by Marco Palma
Vaccines 2025, 13(4), 344; https://doi.org/10.3390/vaccines13040344
Available online: https://www.mdpi.com/2076-393X/13/4/344
11. “Dengue Vaccination: A Practical Guide for Clinicians”
by Kay Choong See
Vaccines 2025, 13(2), 145; https://doi.org/10.3390/vaccines13020145
Available online: https://www.mdpi.com/2076-393X/13/2/145
12. “Human Endogenous Retroviruses as Novel Therapeutic Targets in Neurodegenerative Disorders”
by Elena Rita Simula, Seyedesomaye Jasemi, Davide Cossu, Milena Fais, Ilaria Cossu, Vanna Chessa, Mattia Canu and Leonardo Antonio Sechi
Vaccines 2025, 13(4), 415; https://doi.org/10.3390/vaccines13040415
Available online: https://www.mdpi.com/2076-393X/13/4/415
13. “Past, Present, and Future of Viral Vector Vaccine Platforms: A Comprehensive Review”
by Justin Tang, Md Al Amin and Jian L. Campian
Vaccines 2025, 13(5), 524; https://doi.org/10.3390/vaccines13050524
Available online: https://www.mdpi.com/2076-393X/13/5/524
14. “Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies”
by Sahar Balkhi, Giorgia Bilato, Andrea De Lerma Barbaro, Paola Orecchia, Alessandro Poggi and Lorenzo Mortara
Vaccines 2025, 13(1), 69; https://doi.org/10.3390/vaccines13010069
Available online: https://www.mdpi.com/2076-393X/13/1/69
15. “Maternal Immunization: Current Evidence, Progress, and Challenges”
by Veronica Santilli, Mayla Sgrulletti, Giorgio Costagliola, Alessandra Beni, Maria Felicia Mastrototaro, Davide Montin, Caterina Rizzo, Baldassarre Martire, Michele Miraglia del Giudice and Viviana Moschese on behalf of the Italian Society of Pediatric Allergy and Immunology (SIAIP) Vaccine Committee
Vaccines 2025, 13(5), 450; https://doi.org/10.3390/vaccines13050450
Available online: https://www.mdpi.com/2076-393X/13/5/450
by Ankita Saha, Sounak Ghosh Roy, Richa Dwivedi, Prajna Tripathi, Kamal Kumar, Shashank Manohar Nambiar and Rajiv Pathak
Vaccines 2025, 13(4), 424; https://doi.org/10.3390/vaccines13040424
Available online: https://www.mdpi.com/2076-393X/13/4/424
2. “Advances and Challenges in Aeromonas hydrophila Vaccine Development: Immunological Insights and Future Perspectives”
by Kavi R. Miryala and Banikalyan Swain
Vaccines 2025, 13(2), 202; https://doi.org/10.3390/vaccines13020202
Available online: https://www.mdpi.com/2076-393X/13/2/202
3. “Molecular Farming for Immunization: Current Advances and Future Prospects in Plant-Produced Vaccines”
by Dang-Khoa Vo and Kieu The Loan Trinh
Vaccines 2025, 13(2), 191; https://doi.org/10.3390/vaccines13020191
Available online: https://www.mdpi.com/2076-393X/13/2/191
4. “Revolutionizing Nanovaccines: A New Era of Immunization”
by Mohammed Saleh, Ahmed El-Moghazy, Adel H. Elgohary, WesamEldin I. A. Saber and Yosra A. Helmy
Vaccines 2025, 13(2), 126; https://doi.org/10.3390/vaccines13020126
Available online: https://www.mdpi.com/2076-393X/13/2/126
5. “Pediatric Vaccine Hesitancy in the United States—The Growing Problem and Strategies for Management Including Motivational Interviewing”
by Ashlesha Kaushik, Julia Fomicheva, Nathan Boonstra, Elizabeth Faber, Sandeep Gupta and Helen Kest
Vaccines 2025, 13(2), 115; https://doi.org/10.3390/vaccines13020115
Available online: https://www.mdpi.com/2076-393X/13/2/115
6. “Progress and Challenges in HIV-1 Vaccine Research: A Comprehensive Overview”
by Alex C. Boomgarden and Chitra Upadhyay
Vaccines 2025, 13(2), 148; https://doi.org/10.3390/vaccines13020148
Available online: https://www.mdpi.com/2076-393X/13/2/148
7. “Pertussis in Early Infancy: Diagnostic Challenges, Disease Burden, and Public Health Implications Amidst the 2024 Resurgence, with Emphasis on Maternal Vaccination Strategies”
by Konstantina Leontari, Alexandra Lianou, Andreas G. Tsantes, Filippos Filippatos, Zoi Iliodromiti, Theodora Boutsikou, Styliani Paliatsou, Anastasios E. Chaldoupis, Petros Ioannou, Alexandra Mpakosi et al.
Vaccines 2025, 13(3), 276; https://doi.org/10.3390/vaccines13030276
Available online: https://www.mdpi.com/2076-393X/13/3/276
8. “No Increased Risk of Autoimmune Diseases Following HPV Vaccination: A Systematic Review and Meta-Analysis”
by Filippo Alberto Ferrari, Enrico Ciminello, Marcello Ceccaroni, Matteo Pavone, Violante Di Donato, Giorgia Perniola, Pierluigi Benedetti Panici, Ludovico Muzii, Andrea Giannini, Giuseppe Vizzielli et al.
Vaccines 2025, 13(4), 391; https://doi.org/10.3390/vaccines13040391
Available online: https://www.mdpi.com/2076-393X/13/4/391
9. “The New Era of Pneumococcal Vaccination in Adults: What Is Next?”
by Lale Ozisik
Vaccines 2025, 13(5), 498; https://doi.org/10.3390/vaccines13050498
Available online: https://www.mdpi.com/2076-393X/13/5/498
10. “Advancing Breast Cancer Treatment: The Role of Immunotherapy and Cancer Vaccines in Overcoming Therapeutic Challenges”
by Marco Palma
Vaccines 2025, 13(4), 344; https://doi.org/10.3390/vaccines13040344
Available online: https://www.mdpi.com/2076-393X/13/4/344
11. “Dengue Vaccination: A Practical Guide for Clinicians”
by Kay Choong See
Vaccines 2025, 13(2), 145; https://doi.org/10.3390/vaccines13020145
Available online: https://www.mdpi.com/2076-393X/13/2/145
12. “Human Endogenous Retroviruses as Novel Therapeutic Targets in Neurodegenerative Disorders”
by Elena Rita Simula, Seyedesomaye Jasemi, Davide Cossu, Milena Fais, Ilaria Cossu, Vanna Chessa, Mattia Canu and Leonardo Antonio Sechi
Vaccines 2025, 13(4), 415; https://doi.org/10.3390/vaccines13040415
Available online: https://www.mdpi.com/2076-393X/13/4/415
13. “Past, Present, and Future of Viral Vector Vaccine Platforms: A Comprehensive Review”
by Justin Tang, Md Al Amin and Jian L. Campian
Vaccines 2025, 13(5), 524; https://doi.org/10.3390/vaccines13050524
Available online: https://www.mdpi.com/2076-393X/13/5/524
14. “Efficacy of Anti-Cancer Immune Responses Elicited Using Tumor-Targeted IL-2 Cytokine and Its Derivatives in Combined Preclinical Therapies”
by Sahar Balkhi, Giorgia Bilato, Andrea De Lerma Barbaro, Paola Orecchia, Alessandro Poggi and Lorenzo Mortara
Vaccines 2025, 13(1), 69; https://doi.org/10.3390/vaccines13010069
Available online: https://www.mdpi.com/2076-393X/13/1/69
15. “Maternal Immunization: Current Evidence, Progress, and Challenges”
by Veronica Santilli, Mayla Sgrulletti, Giorgio Costagliola, Alessandra Beni, Maria Felicia Mastrototaro, Davide Montin, Caterina Rizzo, Baldassarre Martire, Michele Miraglia del Giudice and Viviana Moschese on behalf of the Italian Society of Pediatric Allergy and Immunology (SIAIP) Vaccine Committee
Vaccines 2025, 13(5), 450; https://doi.org/10.3390/vaccines13050450
Available online: https://www.mdpi.com/2076-393X/13/5/450