Special Issue "Gene Therapy for Retroviral Infections"
Deadline for manuscript submissions: closed (30 November 2013)
Prof. Dr. Irvin Chen
David Geffen School of Medicine, UCLA, 615 Charles E. Young Dr. South, BSRB, Rm 161, Los Angeles, CA 90095, USA
Phone: +310 825 4793
The main focus of this special issue is to review and present recent gene therapy research relevant to retroviral infections. Current highly active antiviral retroviral therapy (HAART) effectively suppresses HIV viral load to undetectable levels. However, HAART does not cure HIV infection. HIV persists in various cellular reservoirs under HAART and if therapy is ceased, viral loads rapidly rebound. Therefore, stable control of HIV infection without continuous treatment remains a long-term goal of HIV therapy. Because of the recent HIV cure achieved in one patient with D32/D32 homozygous CCR5 deficient bone marrow transplants, there has been emerging interest in developing novel HIV cure strategies. Gene therapy to genetically protect stem cells and/or their progenies from HIV infection may provide life-long protection by a single or a few treatments. We expect that this special issue will facilitate awareness of gene therapy research for the development of novel therapeutic strategies for HIV infection.
Prof. Dr. Irvin Chen
Prof. Dr. Dong Sung An
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed Open Access monthly journal published by MDPI.