Special Issue "Endogenous Retroviruses 2021"

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: 10 September 2021.

Special Issue Editors

Dr. Yingguang Liu
E-Mail Website
Guest Editor
Department of Molecular and Cellular Sciences, Liberty University College of Osteopathic Medicine, 306 Liberty View Lane, Lynchburg, VA 24502, USA
Interests: physiological functions of human endogenous retroviruses; role of endogenous retroviruses in cancer development
Dr. Pieter Borger
E-Mail Website
Co-Guest Editor
Swiss Hepato-Pancreatico-Biliary and Transplantation Center, Department of Surgery & Transplantation, University Hospital Zurich, Rämistrasse 100, CH-8091 Zürich, Switzerland
Interests: Protein Analysis; RNA Analysis; Signaling Pathways; Adaptive Evolution; Transposable Elements Genetics

Special Issue Information

Dear Colleagues,

Endogenous retroviruses (ERVs) fascinate both geneticists and virologists. The sheer abundance of these elements in eutherian genomes, as well as the accumulating knowledge of their essential roles in fundamental physiological processes such as placentation and embryonic development, makes one wonder how mammalian species could have existed without them. On the other hand, there is a growing body of literature concerning the involvement of ERVs in cancer and autoimmune diseases. Is ERV activation a consequence of genomic dysregulation as the disease progresses, or does it play a causal role in initiating these diseases?

In order to answer such foundational questions, inhibition of ERVs is under active investigation as a potential therapeutic approach to multiple diseases. We invite any interested virologist, geneticist, or physician to contribute to a discussion on various aspects of the ERV enigma in this Special Issue. Suggested topics include but are not limited to:

  1. Evolutionary relationships between ERVs and their host species;
  2. Evolutionary relationships between ERVs and modern retroviruses;
  3. Cellular regulation of ERV elements in eutherian genomes;
  4. Physiological functions of ERVs;
  5. Pathogenesis of ERVs;
  6. Targeting ERVs in disease treatment.

Dr. Yingguang Liu
Guest Editor
Dr. Pieter Borger
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endogenous retroviruses
  • evolution
  • reproduction
  • cancer
  • autoimmunity
  • tumorigenesis
  • antiretroviral agents

Published Papers

This special issue is now open for submission.
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