Mechanisms of Inflammation in Long-COVID/Post-COVID-Vaccination Syndrome
A special issue of Vaccines (ISSN 2076-393X).
Deadline for manuscript submissions: 31 August 2026 | Viewed by 5546
Special Issue Editor
Interests: autoimmunity; basic immunology; T-cell; B-cell and dendritic cell biology; transplantation; anti-infectious immune response
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Long-COVID (LC) is a syndrome in which several debilitating symptoms persist for three months or more after COVID-19. Many aspects of this condition are still to be elucidated. Vaccination against COVID-19 can be, sometimes, followed by a post-vaccination syndrome, referred to as PACVS, which partly resembles LC. These pathological conditions are diffused worldwide and demand decisive clinical interventions. It has also been shown that repeated COVID-19 vaccination can induce the development of the IgG4 class of antibodies, instead of more protective classes of antibodies. Both SARS-CoV-2 infections and vaccinations can induce the development or can induce de novo autoimmune phenomena.
This Special Issue welcomes the submission of research articles or review articles that address the mechanisms of LC or the effects of COVID-19 vaccination in the long term. Studies that address the development of IgG4 in LC or in PACVS are also welcome. Moreover, this Special Issue can also include studies that analyze the incidence of LC or PACVS in people with pre-existing conditions, such as chronic diseases, including allergies. Studies that explore the incidence of side effects of vaccination against the virus Sars-CoV-2 or address strategies to improve LC and /or PACVS, via novel pharmacological interventions, will fit in this Special Issue. The effect of vaccination (either protective or non-protective) on LC development is also an issue to clarify, and studies in this field are welcome.
Dr. Loredana Frasca
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Long-COVID/Post-COVID-vaccination
- syndrome
- development of IgG4
- side effects of vaccination
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