Tumor Antigen-Based Anticancer Vaccine and Immunotherapy
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Cancer Vaccines and Immunotherapy".
Deadline for manuscript submissions: closed (28 February 2025) | Viewed by 357
Special Issue Editor
Interests: oncology; virology; molecular biology; cancer research; cancer vaccines
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Anti-cancer vaccines and immunotherapies are the most recent and successful strategies against cancer. Since the early 2000s, focused target therapy has replaced non-selective cytotoxic chemotherapy, leading to significant advancements in cancer treatment. Small interfering molecules and monoclonal antibodies have effectively modulated immune responses but have limited contribution to the active immune response, which is the goal of immunotherapy. This Special Issue focuses on research activities addressing the transformation of immunologically inert tumors into immunologically reactive cancers suitable for specific control or elimination from the host immune system. We welcome manuscripts addressing critical in vitro and in vivo issues to optimize strategies, from identifying tumor-specific antigens and tumor-associated antigen epitopes to exploring immune checkpoint inhibitors.
In this Special Issue, original research articles and reviews are welcome.
Research areas may include the following:
- Identification of tumor-specific antigen (TSA)/tumor-associated antigens (TAA);
- Adjuvants;
- Characterization and selection of inhibitory checkpoints;
- Antigens and CPIs and their temporal administration;
- Regulatory compliance for the development of such molecules and clinical studies.
We look forward to receiving your contributions.
Dr. Franco M. Buonaguro
Guest Editor
Manuscript Submission Information
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Keywords
- immune check point inhibitors (CPIs)
- PD-1/PD-L1 inhibitors
- CTLA-4 inhibitors
- LAG-3 inhibitors
- anti-HPV adjuvant and therapeutic vaccines
- TSAs
- TAAs
- cancer vaccines
- adjuvants for cancer vaccines
- cancer vaccines as neo-adjuvants
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