Big Data and Precision Medicine Series II: Human Papillomavirus and Cancer

Dear Colleagues,

Human papillomaviruses (HPV) have been recognized as the major risk factor for development of nearly all cervical cancers, and a significant fraction of other human carcinoma, arising from mucosal squamous epithelia, including anal, vaginal, vulvar, penile and oropharyngeal cancer. Long-term persistent infections, the integration of viral DNA into the human genome, and constitutive expression of viral oncoproteins contribute to many heterogeneous molecular changes in infected cells, leading to cancer development and progression. Many genetic and epigenetic alterations, as well as complex molecular networks have been identified by “omics” technologies in HPV-related cancer. We welcome submissions of research and review articles on the “omic” landscape of HPV-related cancer to gather current knowledge on the complex process of viral oncology.

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Human papillomavirus-related cancers
• Genomic landscape and cancer driver genes
• Array-based expression profiles
• Epigenomic analysis
• miRNA
• Methylation