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Vaccines
Special Issues
Future Global Vaccination Strategies: Lessons from Early 21st Century Challenges
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Future Global Vaccination Strategies: Lessons from Early 21st Century Challenges

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Human Vaccines and Public Health".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 797

Special Issue Editors

Prof. Dr. Toomas Timpka

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Guest Editor
Department of Health, Medicine, and Caring Sciences, Linköping University, 58183 Linköping, Sweden
Interests: infectious disease epidemiology; vaccination; public health policy
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. James M. Nyce

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Guest Editor
Department of Anthropology, Ball State University, Muncie, IN, USA
Interests: infectious diseases; medical anthropology; vaccination; global biosafety
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Elin A. Gursky

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Guest Editor
College of Osteopathic Medicine, William Carey University, Hattiesburg, MS, USA
Interests: infectious disease epidemiology; vaccination; global health; outbreak mitigation
Special Issues, Collections and Topics in MDPI journals
Dr. Armin Spreco

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Guest Editor
Department of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden
Interests: infectious disease epidemiology; vaccination; outbreak modeling
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,  

A successful immunization system requires the coordination of multiple program components to provide people with the opportunity to be vaccinated. Specifically, this involves procuring vaccines, ensuring their successful delivery, and maintaining proper storage by the cold chain. Health workers must be trained in vaccine management, handling, administration, data recording, reporting, and interacting with vaccinees. It is vital to create community demand for immunization so that caregivers understand the value of vaccination and know when and where to bring their children and themselves for vaccination. The overall coordination, management, and implementation of these activities require political support, sustained financing, supervision, and the appropriate monitoring and use of high-quality data.

In this Special Issue, we welcome original research articles and reviews that discuss global vaccination coverage. The articles can clarify the interrelationship between vaccination programs and policymaking at national, regional, and international levels, and they can include the historical aspects of vaccination programs and the actionable understanding of public health.

You may choose our Joint Special Issue in IJERPH.

Prof. Dr. Toomas Timpka
Prof. Dr. James M. Nyce
Prof. Dr. Elin A. Gursky
Dr. Armin Spreco
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vaccination
  • global health
  • epidemiology
  • immunology
  • virology
  • modeling
  • health systems
  • health policy
  • cross-cultural studies
  • health services research

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Published Papers (1 paper)

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Research

19 pages, 1539 KiB  
Article
Evaluating the Impact of Needle-Free Delivery of Inactivated Polio Vaccine on Nigeria’s Routine Immunization Program: An Implementation Hybrid Trial
by Diwakar Mohan, Mercy Mvundura, Sidney Sampson, Victor Abiola Adepoju, Garba Bello Bakunawa, Chidinma Umebido, Adachi Ekeh, Joe Little, Catherine Daly, Christopher Morgan, Sunday Atobatele, Paul LaBarre and Elizabeth Oliveras
Vaccines 2025, 13(5), 533; https://doi.org/10.3390/vaccines13050533 - 16 May 2025
Viewed by 376
Abstract
Background/Objectives: The Tropis® ID device (PharmaJet®), a needle-free injection system, is a World Health Organization prequalified, hand-held device, which delivers intradermal injections without the use of needles and has previously been used for the delivery of fractional doses of [...] Read more.
Background/Objectives: The Tropis® ID device (PharmaJet®), a needle-free injection system, is a World Health Organization prequalified, hand-held device, which delivers intradermal injections without the use of needles and has previously been used for the delivery of fractional doses of inactivated polio vaccine (fIPV) in campaign and house-to-house settings. This implementation research study aimed to comparatively evaluate the vaccine coverage, cost, feasibility, and acceptability of using Tropis for fIPV for routine immunizations in two states in Nigeria (Kano and Oyo). Methods: The study included: (i) a cluster randomized trial (22 intervention facilities using Tropis for fIPV and 30 control facilities using the standard of care [SoC—full-dose IPV]) to assess the effectiveness in terms of improving the coverage of two doses of IPV, using a coverage survey involving 3433 children (aged 3–12 months); (ii) a pre- and post-implementation micro-costing evaluation involving the intervention facilities to estimate the costs; and (iii) mixed methods assessments (post-training assessment, provider survey, key informant interviews, and focus group discussions) to assess the feasibility and acceptability of fIPV delivery using Tropis. Results: The intention-to-treat analysis among the 3433 children surveyed did not show any difference between the intervention and control groups, primarily due to low compliance (approximately 50% of target beneficiaries reported Tropis use). The more relevant per protocol analysis, adjusting for lower compliance, showed that among those vaccinated with Tropis, second dose IPV coverage was 11.2% higher than the SoC. The delivery of fIPV using Tropis compared to the SoC resulted in incremental program cost savings, ranging from USD 0.07 to USD 1.00 per dose, administered across the scenarios evaluated. High acceptability was seen amongst caregivers (94%), and 95% of healthcare workers preferred Tropis over the SoC. Conclusions: Tropis is effective, feasible, acceptable, and saves costs when used as part of routine immunization programs. Full article
(This article belongs to the Special Issue Future Global Vaccination Strategies: Lessons from Early 21st Century Challenges)
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